Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S5H5M9_LEIDO

TriTrypDb:

LdCL_060005600 , LDHU3_06.0100

Length:

272

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H5M9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5M9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	150	154	PF00656	0.344
CLV_PCSK_SKI1_1	185	189	PF00082	0.347
DOC_MAPK_MEF2A_6	132	140	PF00069	0.286
DOC_PP2B_LxvP_1	161	164	PF13499	0.426
DOC_PP4_FxxP_1	176	179	PF00568	0.369
DOC_USP7_MATH_1	12	16	PF00917	0.447
DOC_USP7_MATH_1	262	266	PF00917	0.442
DOC_USP7_MATH_1	73	77	PF00917	0.413
DOC_USP7_MATH_1	94	98	PF00917	0.374
DOC_WW_Pin1_4	132	137	PF00397	0.292
LIG_14-3-3_CanoR_1	233	237	PF00244	0.431
LIG_14-3-3_CanoR_1	40	47	PF00244	0.442
LIG_deltaCOP1_diTrp_1	56	64	PF00928	0.426
LIG_FHA_1	175	181	PF00498	0.290
LIG_FHA_1	229	235	PF00498	0.342
LIG_FHA_1	24	30	PF00498	0.407
LIG_FHA_2	213	219	PF00498	0.372
LIG_FHA_2	55	61	PF00498	0.468
LIG_LIR_Apic_2	175	179	PF02991	0.398
LIG_LIR_Gen_1	139	149	PF02991	0.308
LIG_LIR_Gen_1	20	29	PF02991	0.411
LIG_LIR_Gen_1	86	94	PF02991	0.358
LIG_LIR_LC3C_4	6	11	PF02991	0.450
LIG_LIR_Nem_3	116	122	PF02991	0.315
LIG_LIR_Nem_3	139	145	PF02991	0.294
LIG_LIR_Nem_3	20	24	PF02991	0.414
LIG_LIR_Nem_3	67	71	PF02991	0.617
LIG_LIR_Nem_3	86	90	PF02991	0.312
LIG_Pex14_1	208	212	PF04695	0.362
LIG_Pex14_2	64	68	PF04695	0.400
LIG_SH2_CRK	142	146	PF00017	0.319
LIG_SH2_CRK	200	204	PF00017	0.309
LIG_SH2_CRK	87	91	PF00017	0.360
LIG_SH2_STAP1	119	123	PF00017	0.308
LIG_SH2_STAP1	142	146	PF00017	0.294
LIG_SH2_STAP1	71	75	PF00017	0.410
LIG_SH2_STAT5	200	203	PF00017	0.319
LIG_SH3_4	209	216	PF00018	0.357
LIG_SUMO_SIM_anti_2	6	13	PF11976	0.451
LIG_SUMO_SIM_par_1	6	13	PF11976	0.451
LIG_TYR_ITIM	198	203	PF00017	0.315
LIG_TYR_ITIM	85	90	PF00017	0.369
LIG_WRC_WIRS_1	173	178	PF05994	0.283
LIG_WRC_WIRS_1	266	271	PF05994	0.420
MOD_CK1_1	265	271	PF00069	0.471
MOD_CK2_1	212	218	PF00069	0.319
MOD_CK2_1	39	45	PF00069	0.434
MOD_CK2_1	54	60	PF00069	0.435
MOD_DYRK1A_RPxSP_1	132	136	PF00069	0.288
MOD_GlcNHglycan	132	135	PF01048	0.281
MOD_GlcNHglycan	150	153	PF01048	0.540
MOD_GlcNHglycan	167	171	PF01048	0.373
MOD_GlcNHglycan	32	35	PF01048	0.395
MOD_GlcNHglycan	75	78	PF01048	0.412
MOD_GSK3_1	132	139	PF00069	0.407
MOD_GSK3_1	162	169	PF00069	0.366
MOD_GSK3_1	208	215	PF00069	0.365
MOD_GSK3_1	220	227	PF00069	0.293
MOD_GSK3_1	228	235	PF00069	0.284
MOD_GSK3_1	265	272	PF00069	0.449
MOD_LATS_1	222	228	PF00433	0.320
MOD_N-GLC_1	17	22	PF02516	0.427
MOD_NEK2_1	166	171	PF00069	0.371
MOD_NEK2_1	30	35	PF00069	0.401
MOD_NEK2_2	154	159	PF00069	0.345
MOD_PIKK_1	39	45	PF00454	0.434
MOD_PKA_2	232	238	PF00069	0.326
MOD_PKA_2	39	45	PF00069	0.434
MOD_Plk_1	12	18	PF00069	0.448
MOD_Plk_2-3	54	60	PF00069	0.449
MOD_Plk_4	141	147	PF00069	0.314
MOD_Plk_4	17	23	PF00069	0.426
MOD_Plk_4	237	243	PF00069	0.507
MOD_Plk_4	25	31	PF00069	0.384
MOD_Plk_4	262	268	PF00069	0.426
MOD_ProDKin_1	132	138	PF00069	0.287
MOD_SUMO_rev_2	67	76	PF00179	0.406
TRG_DiLeu_BaLyEn_6	176	181	PF01217	0.279
TRG_ENDOCYTIC_2	142	145	PF00928	0.318
TRG_ENDOCYTIC_2	200	203	PF00928	0.312
TRG_ENDOCYTIC_2	87	90	PF00928	0.346
TRG_ER_diArg_1	243	246	PF00400	0.540

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NL12	Trypanosomatidae	30%	67%