Amino acid metabolism, 3-mercaptopyruvate sulfurtransferase MST
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | yes | yes: 6 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 12 |
| NetGPI | no | yes: 0, no: 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005829 | cytosol | 2 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
Related structures:
AlphaFold database: A0A3S5H5L1
PDB structure(s): 1okg_A
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000096 | sulfur amino acid metabolic process | 4 | 1 |
| GO:0000097 | sulfur amino acid biosynthetic process | 5 | 1 |
| GO:0006082 | organic acid metabolic process | 3 | 1 |
| GO:0006520 | amino acid metabolic process | 3 | 1 |
| GO:0006534 | cysteine metabolic process | 5 | 1 |
| GO:0006790 | sulfur compound metabolic process | 3 | 1 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 1 |
| GO:0008152 | metabolic process | 1 | 1 |
| GO:0008652 | amino acid biosynthetic process | 4 | 1 |
| GO:0009058 | biosynthetic process | 2 | 1 |
| GO:0009069 | serine family amino acid metabolic process | 5 | 1 |
| GO:0009070 | serine family amino acid biosynthetic process | 6 | 1 |
| GO:0009092 | homoserine metabolic process | 6 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0016053 | organic acid biosynthetic process | 4 | 1 |
| GO:0019343 | cysteine biosynthetic process via cystathionine | 7 | 1 |
| GO:0019344 | cysteine biosynthetic process | 6 | 1 |
| GO:0019346 | transsulfuration | 6 | 1 |
| GO:0019499 | cyanide metabolic process | 3 | 1 |
| GO:0019752 | carboxylic acid metabolic process | 5 | 1 |
| GO:0034641 | cellular nitrogen compound metabolic process | 3 | 1 |
| GO:0043436 | oxoacid metabolic process | 4 | 1 |
| GO:0044237 | cellular metabolic process | 2 | 1 |
| GO:0044238 | primary metabolic process | 2 | 1 |
| GO:0044249 | cellular biosynthetic process | 3 | 1 |
| GO:0044272 | sulfur compound biosynthetic process | 4 | 1 |
| GO:0044281 | small molecule metabolic process | 2 | 1 |
| GO:0044283 | small molecule biosynthetic process | 3 | 1 |
| GO:0046394 | carboxylic acid biosynthetic process | 5 | 1 |
| GO:0050667 | homocysteine metabolic process | 5 | 1 |
| GO:0071704 | organic substance metabolic process | 2 | 1 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 1 |
| GO:1901566 | organonitrogen compound biosynthetic process | 4 | 1 |
| GO:1901576 | organic substance biosynthetic process | 3 | 1 |
| GO:1901605 | alpha-amino acid metabolic process | 4 | 1 |
| GO:1901607 | alpha-amino acid biosynthetic process | 5 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 13 |
| GO:0016740 | transferase activity | 2 | 13 |
| GO:0016782 | transferase activity, transferring sulphur-containing groups | 3 | 13 |
| GO:0016783 | sulfurtransferase activity | 4 | 13 |
| GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity | 5 | 8 |
| GO:0004792 | thiosulfate sulfurtransferase activity | 5 | 4 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 310 | 314 | PF00656 | 0.477 |
| CLV_C14_Caspase3-7 | 332 | 336 | PF00656 | 0.440 |
| CLV_PCSK_SKI1_1 | 13 | 17 | PF00082 | 0.443 |
| CLV_PCSK_SKI1_1 | 159 | 163 | PF00082 | 0.496 |
| CLV_PCSK_SKI1_1 | 359 | 363 | PF00082 | 0.499 |
| DEG_SPOP_SBC_1 | 68 | 72 | PF00917 | 0.565 |
| DOC_CKS1_1 | 149 | 154 | PF01111 | 0.687 |
| DOC_CKS1_1 | 306 | 311 | PF01111 | 0.512 |
| DOC_CYCLIN_yCln2_LP_2 | 271 | 277 | PF00134 | 0.422 |
| DOC_MAPK_gen_1 | 356 | 365 | PF00069 | 0.413 |
| DOC_MAPK_HePTP_8 | 353 | 365 | PF00069 | 0.388 |
| DOC_MAPK_MEF2A_6 | 356 | 365 | PF00069 | 0.387 |
| DOC_PP1_RVXF_1 | 110 | 116 | PF00149 | 0.628 |
| DOC_PP4_FxxP_1 | 15 | 18 | PF00568 | 0.541 |
| DOC_PP4_FxxP_1 | 288 | 291 | PF00568 | 0.573 |
| DOC_USP7_MATH_1 | 209 | 213 | PF00917 | 0.506 |
| DOC_USP7_UBL2_3 | 49 | 53 | PF12436 | 0.652 |
| DOC_USP7_UBL2_3 | 9 | 13 | PF12436 | 0.544 |
| DOC_WW_Pin1_4 | 145 | 150 | PF00397 | 0.699 |
| DOC_WW_Pin1_4 | 305 | 310 | PF00397 | 0.418 |
| LIG_14-3-3_CanoR_1 | 185 | 191 | PF00244 | 0.446 |
| LIG_14-3-3_CanoR_1 | 34 | 38 | PF00244 | 0.569 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.781 |
| LIG_BRCT_BRCA1_1 | 247 | 251 | PF00533 | 0.538 |
| LIG_BRCT_BRCA1_1 | 284 | 288 | PF00533 | 0.490 |
| LIG_FHA_1 | 209 | 215 | PF00498 | 0.581 |
| LIG_FHA_1 | 256 | 262 | PF00498 | 0.388 |
| LIG_FHA_1 | 306 | 312 | PF00498 | 0.483 |
| LIG_FHA_1 | 319 | 325 | PF00498 | 0.343 |
| LIG_FHA_1 | 360 | 366 | PF00498 | 0.381 |
| LIG_Integrin_RGD_1 | 217 | 219 | PF01839 | 0.562 |
| LIG_LIR_Apic_2 | 285 | 291 | PF02991 | 0.562 |
| LIG_LIR_Nem_3 | 27 | 31 | PF02991 | 0.553 |
| LIG_LIR_Nem_3 | 280 | 284 | PF02991 | 0.390 |
| LIG_Pex14_2 | 158 | 162 | PF04695 | 0.581 |
| LIG_PTB_Apo_2 | 125 | 132 | PF02174 | 0.562 |
| LIG_SH2_CRK | 284 | 288 | PF00017 | 0.560 |
| LIG_SH2_STAP1 | 210 | 214 | PF00017 | 0.567 |
| LIG_SH2_STAP1 | 35 | 39 | PF00017 | 0.565 |
| LIG_SH2_STAT5 | 125 | 128 | PF00017 | 0.526 |
| LIG_SH2_STAT5 | 166 | 169 | PF00017 | 0.590 |
| LIG_SH2_STAT5 | 210 | 213 | PF00017 | 0.514 |
| LIG_SH2_STAT5 | 275 | 278 | PF00017 | 0.410 |
| LIG_SH2_STAT5 | 354 | 357 | PF00017 | 0.512 |
| LIG_SH3_2 | 8 | 13 | PF14604 | 0.578 |
| LIG_SH3_3 | 143 | 149 | PF00018 | 0.705 |
| LIG_SH3_3 | 363 | 369 | PF00018 | 0.484 |
| LIG_SH3_3 | 5 | 11 | PF00018 | 0.630 |
| LIG_SH3_3 | 73 | 79 | PF00018 | 0.631 |
| LIG_SUMO_SIM_par_1 | 359 | 364 | PF11976 | 0.395 |
| LIG_TRAF2_1 | 225 | 228 | PF00917 | 0.535 |
| LIG_WRC_WIRS_1 | 246 | 251 | PF05994 | 0.441 |
| MOD_CK1_1 | 148 | 154 | PF00069 | 0.583 |
| MOD_CK1_1 | 252 | 258 | PF00069 | 0.408 |
| MOD_CK1_1 | 282 | 288 | PF00069 | 0.474 |
| MOD_CK2_1 | 222 | 228 | PF00069 | 0.559 |
| MOD_CK2_1 | 277 | 283 | PF00069 | 0.414 |
| MOD_GlcNHglycan | 1 | 4 | PF01048 | 0.794 |
| MOD_GlcNHglycan | 142 | 145 | PF01048 | 0.637 |
| MOD_GlcNHglycan | 181 | 184 | PF01048 | 0.553 |
| MOD_GlcNHglycan | 254 | 257 | PF01048 | 0.423 |
| MOD_GlcNHglycan | 283 | 287 | PF01048 | 0.555 |
| MOD_GlcNHglycan | 339 | 342 | PF01048 | 0.423 |
| MOD_GlcNHglycan | 356 | 359 | PF01048 | 0.418 |
| MOD_GlcNHglycan | 53 | 56 | PF01048 | 0.369 |
| MOD_GSK3_1 | 175 | 182 | PF00069 | 0.538 |
| MOD_GSK3_1 | 237 | 244 | PF00069 | 0.619 |
| MOD_GSK3_1 | 245 | 252 | PF00069 | 0.476 |
| MOD_N-GLC_1 | 62 | 67 | PF02516 | 0.401 |
| MOD_NEK2_1 | 116 | 121 | PF00069 | 0.600 |
| MOD_NEK2_1 | 186 | 191 | PF00069 | 0.435 |
| MOD_NEK2_1 | 249 | 254 | PF00069 | 0.456 |
| MOD_NEK2_2 | 33 | 38 | PF00069 | 0.610 |
| MOD_PKA_2 | 33 | 39 | PF00069 | 0.588 |
| MOD_Plk_1 | 244 | 250 | PF00069 | 0.498 |
| MOD_Plk_2-3 | 41 | 47 | PF00069 | 0.508 |
| MOD_Plk_4 | 232 | 238 | PF00069 | 0.539 |
| MOD_Plk_4 | 245 | 251 | PF00069 | 0.430 |
| MOD_Plk_4 | 349 | 355 | PF00069 | 0.487 |
| MOD_ProDKin_1 | 145 | 151 | PF00069 | 0.701 |
| MOD_ProDKin_1 | 305 | 311 | PF00069 | 0.418 |
| TRG_ENDOCYTIC_2 | 28 | 31 | PF00928 | 0.566 |
| TRG_ENDOCYTIC_2 | 284 | 287 | PF00928 | 0.558 |
| TRG_Pf-PMV_PEXEL_1 | 294 | 298 | PF00026 | 0.478 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1I3F3 | Leptomonas seymouri | 64% | 100% |
| A0A1X0NGL1 | Trypanosomatidae | 51% | 100% |
| A0A1X0NKY9 | Trypanosomatidae | 49% | 98% |
| A0A422NHF2 | Trypanosoma rangeli | 47% | 68% |
| A0A422NMA2 | Trypanosoma rangeli | 47% | 100% |
| A4H4E2 | Leishmania braziliensis | 85% | 100% |
| A4HSL9 | Leishmania infantum | 100% | 100% |
| C9ZTR4 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 48% | 99% |
| E9AKK3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 95% | 100% |
| O64530 | Arabidopsis thaliana | 27% | 98% |
| P00586 | Bos taurus | 29% | 100% |
| P24329 | Rattus norvegicus | 29% | 100% |
| P25324 | Gallus gallus | 28% | 100% |
| P25325 | Homo sapiens | 30% | 100% |
| P31142 | Escherichia coli (strain K12) | 29% | 100% |
| P46635 | Cricetulus griseus | 29% | 100% |
| P52196 | Mus musculus | 29% | 100% |
| P58388 | Escherichia coli O157:H7 | 29% | 100% |
| P59989 | Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) | 24% | 100% |
| P97532 | Rattus norvegicus | 29% | 100% |
| P9WHF4 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | 28% | 100% |
| P9WHF5 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 28% | 100% |
| P9WHF8 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | 24% | 100% |
| P9WHF9 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 24% | 100% |
| Q08686 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 24% | 100% |
| Q16762 | Homo sapiens | 30% | 100% |
| Q24JL3 | Arabidopsis thaliana | 26% | 100% |
| Q7K9G0 | Leishmania major | 96% | 100% |
| Q99J99 | Mus musculus | 29% | 100% |
| Q9I452 | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 34% | 100% |
| Q9USJ1 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 28% | 100% |
| V5BNL9 | Trypanosoma cruzi | 52% | 96% |