LeishMANIAdb
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Vta1_like_putative/Pfam:PF04652

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Vta1_like_putative/Pfam:PF04652
Gene product:
Vta1 like, putative
Species:
Leishmania donovani
UniProt:
A0A3S5H5J7_LEIDO
TriTrypDb:
LdBPK_050740.1 , LdCL_050012500 , LDHU3_05.0830
Length:
364

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) yes yes: 4
Forrest at al. (procyclic) yes yes: 4
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 6
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
TermNameLevelCount
GO:0005768 endosome 7 1
GO:0005770 late endosome 8 1
GO:0005771 multivesicular body 9 1
GO:0010008 endosome membrane 5 8
GO:0012506 vesicle membrane 4 8
GO:0016020 membrane 2 8
GO:0030659 cytoplasmic vesicle membrane 5 8
GO:0031090 organelle membrane 3 8
GO:0031410 cytoplasmic vesicle 6 1
GO:0031982 vesicle 4 1
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Expansion

Sequence features

A0A3S5H5J7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5J7

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 8
GO:0007034 vacuolar transport 4 8
GO:0008104 protein localization 4 8
GO:0009987 cellular process 1 8
GO:0015031 protein transport 4 8
GO:0016192 vesicle-mediated transport 4 8
GO:0016197 endosomal transport 4 8
GO:0032509 endosome transport via multivesicular body sorting pathway 5 8
GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 6 8
GO:0033036 macromolecule localization 2 8
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 65 69 PF00656 0.632
CLV_PCSK_SKI1_1 146 150 PF00082 0.370
CLV_PCSK_SKI1_1 156 160 PF00082 0.357
CLV_PCSK_SKI1_1 20 24 PF00082 0.339
CLV_PCSK_SKI1_1 87 91 PF00082 0.382
CLV_PCSK_SKI1_1 92 96 PF00082 0.355
DEG_COP1_1 286 294 PF00400 0.717
DEG_SPOP_SBC_1 296 300 PF00917 0.778
DOC_CKS1_1 230 235 PF01111 0.740
DOC_CKS1_1 240 245 PF01111 0.807
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I8N6 Leptomonas seymouri 56% 97%
A0A0S4IWD6 Bodo saltans 43% 100%
A4H4B7 Leishmania braziliensis 73% 100%
A4HSJ6 Leishmania infantum 100% 100%
E9AKI0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 99%
Q32L63 Bos taurus 26% 100%
Q4QJC8 Leishmania major 92% 100%
Q5R5W5 Pongo abelii 26% 100%
Q9CR26 Mus musculus 28% 100%
Q9NP79 Homo sapiens 26% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS