LeishMANIAdb
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Cytochrome c oxidase biogenesis protein Cmc1 like, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Cytochrome c oxidase biogenesis protein Cmc1 like, putative
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H5D5_LEIDO
TriTrypDb:
LdBPK_040930.1 , LdCL_040014900 , LDHU3_04.1170
Length:
148

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H5D5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5D5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 112 114 PF00675 0.601
CLV_NRD_NRD_1 139 141 PF00675 0.592
CLV_NRD_NRD_1 89 91 PF00675 0.565
CLV_PCSK_KEX2_1 139 141 PF00082 0.592
CLV_PCSK_SKI1_1 139 143 PF00082 0.515
CLV_PCSK_SKI1_1 38 42 PF00082 0.425
DEG_SCF_FBW7_1 14 20 PF00400 0.605
DOC_CKS1_1 14 19 PF01111 0.605
DOC_PP4_FxxP_1 130 133 PF00568 0.509
DOC_USP7_MATH_1 6 10 PF00917 0.565
DOC_WW_Pin1_4 13 18 PF00397 0.676
LIG_14-3-3_CanoR_1 68 76 PF00244 0.414
LIG_BIR_II_1 1 5 PF00653 0.589
LIG_BIR_III_4 117 121 PF00653 0.563
LIG_FHA_1 14 20 PF00498 0.674
LIG_LIR_Apic_2 128 133 PF02991 0.515
LIG_Pex14_1 92 96 PF04695 0.428
LIG_Rb_pABgroove_1 47 55 PF01858 0.442
LIG_SH2_STAP1 96 100 PF00017 0.449
LIG_SH2_STAT5 136 139 PF00017 0.526
LIG_SUMO_SIM_anti_2 48 54 PF11976 0.452
MOD_GlcNHglycan 144 147 PF01048 0.605
MOD_GlcNHglycan 22 25 PF01048 0.507
MOD_GlcNHglycan 8 11 PF01048 0.675
MOD_GSK3_1 13 20 PF00069 0.601
MOD_N-GLC_1 27 32 PF02516 0.470
MOD_NEK2_1 76 81 PF00069 0.465
MOD_PIKK_1 43 49 PF00454 0.435
MOD_PKA_2 43 49 PF00069 0.435
MOD_PKA_2 6 12 PF00069 0.567
MOD_PKA_2 76 82 PF00069 0.461
MOD_Plk_4 125 131 PF00069 0.535
MOD_Plk_4 70 76 PF00069 0.486
MOD_ProDKin_1 13 19 PF00069 0.674
MOD_SUMO_rev_2 95 100 PF00179 0.505
TRG_DiLeu_BaLyEn_6 101 106 PF01217 0.470
TRG_ER_diArg_1 138 140 PF00400 0.584
TRG_ER_diArg_1 56 59 PF00400 0.417

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCX0 Leptomonas seymouri 79% 100%
A0A0S4IMT7 Bodo saltans 68% 100%
A0A1X0NLQ6 Trypanosomatidae 69% 100%
A4H3Y6 Leishmania braziliensis 94% 100%
A4HS86 Leishmania infantum 99% 100%
C9ZY82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 66% 100%
E9AK74 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS