Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H5A2_LEIDO

TriTrypDb:

LdBPK_040390.1 , LdCL_040009400 , LDHU3_04.0520

Length:

1121

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H5A2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5A2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	112	116	PF00656	0.690
CLV_C14_Caspase3-7	381	385	PF00656	0.690
CLV_C14_Caspase3-7	705	709	PF00656	0.735
CLV_C14_Caspase3-7	907	911	PF00656	0.661
CLV_C14_Caspase3-7	916	920	PF00656	0.621
CLV_NRD_NRD_1	100	102	PF00675	0.730
CLV_NRD_NRD_1	106	108	PF00675	0.678
CLV_NRD_NRD_1	132	134	PF00675	0.679
CLV_NRD_NRD_1	2	4	PF00675	0.598
CLV_NRD_NRD_1	209	211	PF00675	0.672

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A4H3W1	Leishmania braziliensis	63%	95%
A4HS35	Leishmania infantum	100%	100%
E9AK22	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q9NFA7	Leishmania major	89%	99%

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