Surface antigen-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

surface antigen-like protein

Species:

Leishmania donovani

UniProt:

A0A3S5H585_LEIDO

TriTrypDb:

LdBPK_040190.1 , LdCL_040007400 , LDHU3_04.0260

Length:

182

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 4, no: 0
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H585

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H585

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	4	8	PF00082	0.540
DEG_SPOP_SBC_1	90	94	PF00917	0.397
DOC_MAPK_MEF2A_6	162	170	PF00069	0.592
DOC_USP7_MATH_1	145	149	PF00917	0.484
DOC_USP7_MATH_1	153	157	PF00917	0.452
DOC_USP7_MATH_1	35	39	PF00917	0.572
DOC_USP7_MATH_1	79	83	PF00917	0.552
DOC_USP7_MATH_1	89	93	PF00917	0.378
DOC_WW_Pin1_4	100	105	PF00397	0.405
DOC_WW_Pin1_4	27	32	PF00397	0.519
LIG_14-3-3_CanoR_1	135	144	PF00244	0.430
LIG_14-3-3_CanoR_1	162	167	PF00244	0.593
LIG_14-3-3_CanoR_1	36	42	PF00244	0.553
LIG_BIR_II_1	1	5	PF00653	0.553
LIG_BRCT_BRCA1_1	66	70	PF00533	0.531
LIG_DLG_GKlike_1	162	170	PF00625	0.592
LIG_FHA_1	161	167	PF00498	0.514
LIG_FHA_1	71	77	PF00498	0.623
LIG_LIR_LC3C_4	163	168	PF02991	0.512
LIG_LIR_Nem_3	146	152	PF02991	0.605
LIG_PDZ_Class_1	177	182	PF00595	0.602
LIG_PTAP_UEV_1	30	35	PF05743	0.522
LIG_SH3_2	31	36	PF14604	0.638
LIG_SH3_3	28	34	PF00018	0.610
LIG_SUMO_SIM_anti_2	171	177	PF11976	0.416
LIG_SUMO_SIM_par_1	163	171	PF11976	0.444
MOD_CK1_1	138	144	PF00069	0.464
MOD_CK1_1	23	29	PF00069	0.627
MOD_CK1_1	40	46	PF00069	0.647
MOD_CK1_1	49	55	PF00069	0.590
MOD_CK1_1	57	63	PF00069	0.522
MOD_GlcNHglycan	140	143	PF01048	0.446
MOD_GlcNHglycan	31	34	PF01048	0.618
MOD_GlcNHglycan	57	60	PF01048	0.652
MOD_GSK3_1	162	169	PF00069	0.585
MOD_GSK3_1	20	27	PF00069	0.618
MOD_GSK3_1	43	50	PF00069	0.742
MOD_GSK3_1	51	58	PF00069	0.638
MOD_GSK3_1	62	69	PF00069	0.629
MOD_GSK3_1	70	77	PF00069	0.594
MOD_GSK3_1	79	86	PF00069	0.405
MOD_N-GLC_1	54	59	PF02516	0.589
MOD_N-GLC_1	62	67	PF02516	0.583
MOD_N-GLC_2	97	99	PF02516	0.534
MOD_NEK2_1	161	166	PF00069	0.615
MOD_NEK2_1	174	179	PF00069	0.590
MOD_NEK2_1	70	75	PF00069	0.510
MOD_NEK2_2	145	150	PF00069	0.484
MOD_OFUCOSY	114	120	PF10250	0.476
MOD_PKA_2	161	167	PF00069	0.594
MOD_PKA_2	35	41	PF00069	0.581
MOD_Plk_1	23	29	PF00069	0.592
MOD_Plk_4	15	21	PF00069	0.504
MOD_Plk_4	162	168	PF00069	0.721
MOD_ProDKin_1	100	106	PF00069	0.403
MOD_ProDKin_1	27	33	PF00069	0.628

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HS15	Leishmania infantum	99%	100%
E9AK02	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q9XZY0	Leishmania major	88%	100%