BZIP domain-containing protein

Quick info Annotations Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H579_LEIDO

TriTrypDb:

LdBPK_040140.1 , LdCL_040006500 , LDHU3_04.0160

Length:

158

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3S5H579

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H579

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	47	51	PF00656	0.412
CLV_NRD_NRD_1	118	120	PF00675	0.459
CLV_NRD_NRD_1	127	129	PF00675	0.480
CLV_PCSK_KEX2_1	118	120	PF00082	0.459
CLV_PCSK_SKI1_1	133	137	PF00082	0.441
CLV_PCSK_SKI1_1	63	67	PF00082	0.424
DOC_CYCLIN_RxL_1	60	69	PF00134	0.539
DOC_MAPK_gen_1	133	141	PF00069	0.567
DOC_PP2B_LxvP_1	15	18	PF13499	0.545
DOC_USP7_MATH_1	72	76	PF00917	0.596
DOC_USP7_UBL2_3	129	133	PF12436	0.442
DOC_WW_Pin1_4	41	46	PF00397	0.669
DOC_WW_Pin1_4	89	94	PF00397	0.542
LIG_14-3-3_CanoR_1	102	111	PF00244	0.430
LIG_FHA_1	134	140	PF00498	0.566
LIG_FHA_1	59	65	PF00498	0.427
LIG_LIR_Gen_1	3	11	PF02991	0.371
LIG_LIR_Nem_3	3	7	PF02991	0.369
LIG_LIR_Nem_3	59	65	PF02991	0.470
LIG_SH2_GRB2like	10	13	PF00017	0.382
LIG_SH2_SRC	10	13	PF00017	0.499
LIG_SH2_STAT3	22	25	PF00017	0.522
LIG_SH2_STAT5	10	13	PF00017	0.382
LIG_SH3_3	61	67	PF00018	0.436
LIG_SH3_3	90	96	PF00018	0.557
MOD_CK1_1	37	43	PF00069	0.616
MOD_CK1_1	44	50	PF00069	0.496
MOD_CK1_1	52	58	PF00069	0.366
MOD_CK1_1	80	86	PF00069	0.588
MOD_CK1_1	94	100	PF00069	0.596
MOD_GlcNHglycan	32	35	PF01048	0.669
MOD_GlcNHglycan	36	39	PF01048	0.602
MOD_GlcNHglycan	50	54	PF01048	0.383
MOD_GlcNHglycan	74	77	PF01048	0.561
MOD_GlcNHglycan	79	82	PF01048	0.544
MOD_GSK3_1	139	146	PF00069	0.584
MOD_GSK3_1	30	37	PF00069	0.587
MOD_GSK3_1	54	61	PF00069	0.451
MOD_GSK3_1	72	79	PF00069	0.429
MOD_PIKK_1	2	8	PF00454	0.397
MOD_PKA_1	133	139	PF00069	0.443
MOD_PKA_2	77	83	PF00069	0.634
MOD_Plk_1	2	8	PF00069	0.373
MOD_Plk_1	49	55	PF00069	0.444
MOD_Plk_1	58	64	PF00069	0.385
MOD_ProDKin_1	41	47	PF00069	0.662
MOD_ProDKin_1	89	95	PF00069	0.541
TRG_ER_diArg_1	117	119	PF00400	0.454
TRG_ER_diArg_1	154	157	PF00400	0.566

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3X6	Leptomonas seymouri	77%	99%
A0A1X0NLW6	Trypanosomatidae	46%	100%
A0A422NND8	Trypanosoma rangeli	43%	100%
A4H3T4	Leishmania braziliensis	89%	100%
A4HS09	Leishmania infantum	100%	100%
C9ZY07	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E9ACP6	Leishmania major	98%	100%
E9AJZ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	98%