Dehydrogenase/oxidoreductase-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

dehydrogenase/oxidoreductase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S5H517_LEIDO

TriTrypDb:

LdBPK_020700.1 , LdCL_020012500

Length:

181

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H517

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H517

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	134	140	PF00089	0.626
CLV_NRD_NRD_1	103	105	PF00675	0.619
CLV_NRD_NRD_1	127	129	PF00675	0.754
CLV_NRD_NRD_1	161	163	PF00675	0.571
CLV_PCSK_KEX2_1	103	105	PF00082	0.616
CLV_PCSK_KEX2_1	127	129	PF00082	0.744
CLV_PCSK_KEX2_1	161	163	PF00082	0.571
DEG_SPOP_SBC_1	144	148	PF00917	0.615
DOC_MAPK_gen_1	161	168	PF00069	0.490
DOC_MAPK_HePTP_8	158	170	PF00069	0.489
DOC_MAPK_MEF2A_6	161	170	PF00069	0.481
DOC_MAPK_MEF2A_6	24	31	PF00069	0.477
DOC_MAPK_NFAT4_5	24	32	PF00069	0.492
DOC_PP1_RVXF_1	165	171	PF00149	0.419
DOC_PP4_FxxP_1	172	175	PF00568	0.481
DOC_USP7_MATH_1	145	149	PF00917	0.614
DOC_WW_Pin1_4	108	113	PF00397	0.630
DOC_WW_Pin1_4	146	151	PF00397	0.594
DOC_WW_Pin1_4	45	50	PF00397	0.729
DOC_WW_Pin1_4	52	57	PF00397	0.592
LIG_14-3-3_CanoR_1	104	113	PF00244	0.628
LIG_APCC_ABBAyCdc20_2	103	109	PF00400	0.624
LIG_BIR_III_2	18	22	PF00653	0.704
LIG_CtBP_PxDLS_1	62	66	PF00389	0.733
LIG_FHA_1	175	181	PF00498	0.497
LIG_FHA_1	79	85	PF00498	0.722
LIG_SH3_3	147	153	PF00018	0.576
MOD_CK1_1	108	114	PF00069	0.639
MOD_CK1_1	122	128	PF00069	0.548
MOD_CK1_1	146	152	PF00069	0.588
MOD_CK1_1	173	179	PF00069	0.489
MOD_CK1_1	85	91	PF00069	0.670
MOD_CK2_1	118	124	PF00069	0.649
MOD_Cter_Amidation	125	128	PF01082	0.633
MOD_GlcNHglycan	10	13	PF01048	0.545
MOD_GSK3_1	114	121	PF00069	0.728
MOD_GSK3_1	170	177	PF00069	0.476
MOD_GSK3_1	4	11	PF00069	0.567
MOD_GSK3_1	78	85	PF00069	0.725
MOD_GSK3_1	86	93	PF00069	0.557
MOD_N-GLC_2	35	37	PF02516	0.471
MOD_NEK2_1	170	175	PF00069	0.489
MOD_NEK2_1	23	28	PF00069	0.687
MOD_NEK2_1	4	9	PF00069	0.668
MOD_PKA_1	161	167	PF00069	0.495
MOD_PKA_2	161	167	PF00069	0.495
MOD_PKA_2	23	29	PF00069	0.495
MOD_PKA_2	4	10	PF00069	0.664
MOD_PKA_2	90	96	PF00069	0.729
MOD_Plk_1	5	11	PF00069	0.563
MOD_Plk_4	82	88	PF00069	0.708
MOD_ProDKin_1	108	114	PF00069	0.629
MOD_ProDKin_1	146	152	PF00069	0.588
MOD_ProDKin_1	45	51	PF00069	0.729
MOD_ProDKin_1	52	58	PF00069	0.587
TRG_ER_diArg_1	160	162	PF00400	0.579
TRG_Pf-PMV_PEXEL_1	104	109	PF00026	0.625

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HRR8	Leishmania infantum	99%	100%
E9ACE7	Leishmania major	77%	100%
E9ACX6	Leishmania major	77%	100%