LeishMANIAdb
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Glycosyltransferase (GlcNAc), putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Glycosyltransferase (GlcNAc), putative
Gene product:
glycosyltransferase (GlcNAc), putative
Species:
Leishmania donovani
UniProt:
A0A3S5H4Z0_LEIDO
TriTrypDb:
LdBPK_020210.1 * , LdCL_020007500 , LDHU3_02.0310
Length:
902

Annotations

LeishMANIAdb annotations

A conserved glycosyltransferase enzyme. Only expanded in T cruzi lineage.. Localization: Golgi (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 10
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

A0A3S5H4Z0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H4Z0

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 2
GO:0016740 transferase activity 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 105 109 PF00656 0.701
CLV_C14_Caspase3-7 246 250 PF00656 0.694
CLV_C14_Caspase3-7 259 263 PF00656 0.581
CLV_MEL_PAP_1 428 434 PF00089 0.428
CLV_NRD_NRD_1 106 108 PF00675 0.505
CLV_NRD_NRD_1 131 133 PF00675 0.500
CLV_NRD_NRD_1 147 149 PF00675 0.460
CLV_NRD_NRD_1 154 156 PF00675 0.439
CLV_NRD_NRD_1 157 159 PF00675 0.442
CLV_NRD_NRD_1 166 168 PF00675 0.347
CLV_NRD_NRD_1 231 233 PF00675 0.507
CLV_NRD_NRD_1 333 335 PF00675 0.553
CLV_NRD_NRD_1 349 351 PF00675 0.515
CLV_NRD_NRD_1 401 403 PF00675 0.454
CLV_NRD_NRD_1 665 667 PF00675 0.347
CLV_PCSK_FUR_1 155 159 PF00082 0.405
CLV_PCSK_FUR_1 331 335 PF00082 0.536
CLV_PCSK_KEX2_1 106 108 PF00082 0.525
CLV_PCSK_KEX2_1 131 133 PF00082 0.510
CLV_PCSK_KEX2_1 147 149 PF00082 0.463
CLV_PCSK_KEX2_1 153 155 PF00082 0.436
CLV_PCSK_KEX2_1 157 159 PF00082 0.440
CLV_PCSK_KEX2_1 25 27 PF00082 0.625
CLV_PCSK_KEX2_1 333 335 PF00082 0.553
CLV_PCSK_KEX2_1 401 403 PF00082 0.457
CLV_PCSK_KEX2_1 665 667 PF00082 0.347
CLV_PCSK_PC1ET2_1 25 27 PF00082 0.644
CLV_PCSK_PC7_1 153 159 PF00082 0.402
CLV_PCSK_PC7_1 329 335 PF00082 0.533
CLV_PCSK_SKI1_1 131 135 PF00082 0.483
CLV_PCSK_SKI1_1 158 162 PF00082 0.435
CLV_PCSK_SKI1_1 22 26 PF00082 0.658
CLV_PCSK_SKI1_1 233 237 PF00082 0.523
CLV_PCSK_SKI1_1 671 675 PF00082 0.284
DEG_APCC_DBOX_1 17 25 PF00400 0.488
DEG_COP1_1 542 550 PF00400 0.533
DOC_ANK_TNKS_1 241 248 PF00023 0.635
DOC_CDC14_PxL_1 511 519 PF14671 0.513
DOC_CKS1_1 550 555 PF01111 0.553
DOC_CYCLIN_RxL_1 128 137 PF00134 0.644
DOC_CYCLIN_RxL_1 20 32 PF00134 0.455
DOC_CYCLIN_RxL_1 33 47 PF00134 0.371
DOC_CYCLIN_RxL_1 799 810 PF00134 0.493
DOC_CYCLIN_yCln2_LP_2 749 755 PF00134 0.484
DOC_MAPK_gen_1 33 43 PF00069 0.457
DOC_MAPK_gen_1 522 532 PF00069 0.476
DOC_MAPK_gen_1 830 837 PF00069 0.476
DOC_MAPK_MEF2A_6 122 130 PF00069 0.579
DOC_MAPK_MEF2A_6 525 534 PF00069 0.476
DOC_MAPK_MEF2A_6 638 646 PF00069 0.553
DOC_PP1_RVXF_1 37 44 PF00149 0.479
DOC_PP1_RVXF_1 800 807 PF00149 0.553
DOC_PP1_RVXF_1 832 838 PF00149 0.484
DOC_PP2B_LxvP_1 461 464 PF13499 0.649
DOC_PP4_FxxP_1 432 435 PF00568 0.719
DOC_SPAK_OSR1_1 431 435 PF12202 0.713
DOC_USP7_MATH_1 2 6 PF00917 0.563
DOC_USP7_MATH_1 201 205 PF00917 0.633
DOC_USP7_MATH_1 276 280 PF00917 0.739
DOC_USP7_MATH_1 435 439 PF00917 0.651
DOC_USP7_MATH_1 51 55 PF00917 0.496
DOC_WW_Pin1_4 354 359 PF00397 0.736
DOC_WW_Pin1_4 453 458 PF00397 0.640
DOC_WW_Pin1_4 540 545 PF00397 0.572
DOC_WW_Pin1_4 549 554 PF00397 0.486
DOC_WW_Pin1_4 796 801 PF00397 0.484
LIG_14-3-3_CanoR_1 122 130 PF00244 0.649
LIG_14-3-3_CanoR_1 132 142 PF00244 0.619
LIG_14-3-3_CanoR_1 157 163 PF00244 0.690
LIG_14-3-3_CanoR_1 167 176 PF00244 0.623
LIG_14-3-3_CanoR_1 301 307 PF00244 0.774
LIG_14-3-3_CanoR_1 33 39 PF00244 0.485
LIG_14-3-3_CanoR_1 401 409 PF00244 0.667
LIG_14-3-3_CanoR_1 579 584 PF00244 0.476
LIG_14-3-3_CanoR_1 692 698 PF00244 0.484
LIG_14-3-3_CanoR_1 735 743 PF00244 0.493
LIG_14-3-3_CanoR_1 789 798 PF00244 0.486
LIG_14-3-3_CanoR_1 811 815 PF00244 0.513
LIG_14-3-3_CanoR_1 90 100 PF00244 0.682
LIG_Actin_WH2_2 602 618 PF00022 0.513
LIG_APCC_ABBAyCdc20_2 725 731 PF00400 0.533
LIG_FHA_1 297 303 PF00498 0.705
LIG_FHA_1 496 502 PF00498 0.563
LIG_FHA_1 550 556 PF00498 0.530
LIG_FHA_1 641 647 PF00498 0.547
LIG_FHA_1 659 665 PF00498 0.430
LIG_FHA_1 693 699 PF00498 0.484
LIG_FHA_2 103 109 PF00498 0.697
LIG_FHA_2 187 193 PF00498 0.643
LIG_FHA_2 257 263 PF00498 0.684
LIG_FHA_2 318 324 PF00498 0.603
LIG_FHA_2 477 483 PF00498 0.649
LIG_FHA_2 593 599 PF00498 0.485
LIG_IBAR_NPY_1 857 859 PF08397 0.493
LIG_LIR_Apic_2 430 435 PF02991 0.712
LIG_LIR_Apic_2 552 557 PF02991 0.553
LIG_LIR_Gen_1 304 315 PF02991 0.731
LIG_LIR_Gen_1 390 400 PF02991 0.650
LIG_LIR_Gen_1 418 428 PF02991 0.611
LIG_LIR_Gen_1 500 508 PF02991 0.500
LIG_LIR_Gen_1 706 717 PF02991 0.443
LIG_LIR_Gen_1 731 741 PF02991 0.476
LIG_LIR_Gen_1 856 867 PF02991 0.476
LIG_LIR_Nem_3 304 310 PF02991 0.723
LIG_LIR_Nem_3 390 395 PF02991 0.645
LIG_LIR_Nem_3 418 424 PF02991 0.618
LIG_LIR_Nem_3 500 505 PF02991 0.500
LIG_LIR_Nem_3 549 554 PF02991 0.484
LIG_LIR_Nem_3 687 691 PF02991 0.472
LIG_LIR_Nem_3 706 712 PF02991 0.452
LIG_LIR_Nem_3 731 736 PF02991 0.476
LIG_LIR_Nem_3 761 765 PF02991 0.491
LIG_LIR_Nem_3 792 798 PF02991 0.489
LIG_LIR_Nem_3 856 862 PF02991 0.459
LIG_LIR_Nem_3 880 884 PF02991 0.498
LIG_LIR_Nem_3 892 898 PF02991 0.608
LIG_MYND_1 544 548 PF01753 0.484
LIG_MYND_1 553 557 PF01753 0.484
LIG_MYND_3 190 194 PF01753 0.702
LIG_NRBOX 195 201 PF00104 0.699
LIG_NRBOX 66 72 PF00104 0.460
LIG_PCNA_yPIPBox_3 866 879 PF02747 0.484
LIG_Pex14_1 791 795 PF04695 0.484
LIG_Pex14_2 652 656 PF04695 0.484
LIG_Pex14_2 703 707 PF04695 0.484
LIG_Pex14_2 758 762 PF04695 0.533
LIG_PTB_Apo_2 727 734 PF02174 0.533
LIG_PTB_Phospho_1 727 733 PF10480 0.533
LIG_SH2_CRK 403 407 PF00017 0.693
LIG_SH2_CRK 421 425 PF00017 0.557
LIG_SH2_NCK_1 386 390 PF00017 0.634
LIG_SH2_NCK_1 421 425 PF00017 0.674
LIG_SH2_NCK_1 729 733 PF00017 0.468
LIG_SH2_PTP2 531 534 PF00017 0.500
LIG_SH2_PTP2 733 736 PF00017 0.553
LIG_SH2_PTP2 859 862 PF00017 0.459
LIG_SH2_SRC 859 862 PF00017 0.493
LIG_SH2_SRC 879 882 PF00017 0.431
LIG_SH2_STAP1 421 425 PF00017 0.589
LIG_SH2_STAP1 786 790 PF00017 0.484
LIG_SH2_STAT3 825 828 PF00017 0.472
LIG_SH2_STAT5 478 481 PF00017 0.680
LIG_SH2_STAT5 531 534 PF00017 0.500
LIG_SH2_STAT5 551 554 PF00017 0.553
LIG_SH2_STAT5 601 604 PF00017 0.493
LIG_SH2_STAT5 697 700 PF00017 0.505
LIG_SH2_STAT5 709 712 PF00017 0.506
LIG_SH2_STAT5 733 736 PF00017 0.553
LIG_SH2_STAT5 777 780 PF00017 0.484
LIG_SH2_STAT5 809 812 PF00017 0.497
LIG_SH2_STAT5 825 828 PF00017 0.461
LIG_SH2_STAT5 859 862 PF00017 0.459
LIG_SH3_1 767 773 PF00018 0.484
LIG_SH3_3 366 372 PF00018 0.734
LIG_SH3_3 767 773 PF00018 0.484
LIG_SH3_3 846 852 PF00018 0.553
LIG_SH3_3 895 901 PF00018 0.608
LIG_SUMO_SIM_anti_2 308 314 PF11976 0.731
LIG_SUMO_SIM_anti_2 455 462 PF11976 0.625
LIG_SUMO_SIM_anti_2 640 648 PF11976 0.503
LIG_SUMO_SIM_par_1 640 648 PF11976 0.508
LIG_SUMO_SIM_par_1 82 88 PF11976 0.485
LIG_TRAF2_1 209 212 PF00917 0.708
LIG_TRAF2_1 339 342 PF00917 0.698
LIG_TYR_ITIM 395 400 PF00017 0.655
LIG_UBA3_1 162 168 PF00899 0.702
LIG_UBA3_1 663 671 PF00899 0.553
LIG_WRC_WIRS_1 294 299 PF05994 0.678
LIG_WRC_WIRS_1 704 709 PF05994 0.443
LIG_WRC_WIRS_1 759 764 PF05994 0.493
MOD_CDC14_SPxK_1 799 802 PF00782 0.503
MOD_CDK_SPxK_1 796 802 PF00069 0.553
MOD_CDK_SPxxK_3 354 361 PF00069 0.736
MOD_CK1_1 121 127 PF00069 0.633
MOD_CK1_1 296 302 PF00069 0.705
MOD_CK1_1 456 462 PF00069 0.621
MOD_CK1_1 5 11 PF00069 0.486
MOD_CK1_1 504 510 PF00069 0.475
MOD_CK1_1 761 767 PF00069 0.513
MOD_CK1_1 819 825 PF00069 0.450
MOD_CK2_1 186 192 PF00069 0.645
MOD_CK2_1 292 298 PF00069 0.778
MOD_CK2_1 317 323 PF00069 0.603
MOD_CK2_1 592 598 PF00069 0.522
MOD_CK2_1 716 722 PF00069 0.483
MOD_Cter_Amidation 230 233 PF01082 0.518
MOD_GlcNHglycan 123 126 PF01048 0.471
MOD_GlcNHglycan 169 172 PF01048 0.424
MOD_GlcNHglycan 365 369 PF01048 0.520
MOD_GlcNHglycan 4 7 PF01048 0.709
MOD_GlcNHglycan 403 406 PF01048 0.555
MOD_GlcNHglycan 421 424 PF01048 0.369
MOD_GlcNHglycan 812 815 PF01048 0.309
MOD_GSK3_1 182 189 PF00069 0.674
MOD_GSK3_1 292 299 PF00069 0.706
MOD_GSK3_1 410 417 PF00069 0.648
MOD_GSK3_1 497 504 PF00069 0.478
MOD_GSK3_1 588 595 PF00069 0.443
MOD_GSK3_1 785 792 PF00069 0.465
MOD_GSK3_1 819 826 PF00069 0.443
MOD_GSK3_1 838 845 PF00069 0.386
MOD_N-GLC_1 158 163 PF02516 0.508
MOD_N-GLC_1 51 56 PF02516 0.587
MOD_N-GLC_1 853 858 PF02516 0.284
MOD_NEK2_1 100 105 PF00069 0.676
MOD_NEK2_1 143 148 PF00069 0.607
MOD_NEK2_1 186 191 PF00069 0.737
MOD_NEK2_1 271 276 PF00069 0.714
MOD_NEK2_1 520 525 PF00069 0.468
MOD_NEK2_1 57 62 PF00069 0.415
MOD_NEK2_1 590 595 PF00069 0.463
MOD_NEK2_1 659 664 PF00069 0.498
MOD_NEK2_1 703 708 PF00069 0.475
MOD_NEK2_1 758 763 PF00069 0.473
MOD_NEK2_1 785 790 PF00069 0.452
MOD_NEK2_1 838 843 PF00069 0.493
MOD_NEK2_1 93 98 PF00069 0.654
MOD_NEK2_2 201 206 PF00069 0.581
MOD_PIKK_1 51 57 PF00454 0.495
MOD_PIKK_1 618 624 PF00454 0.493
MOD_PIKK_1 819 825 PF00454 0.480
MOD_PKA_1 167 173 PF00069 0.600
MOD_PKA_1 401 407 PF00069 0.642
MOD_PKA_2 121 127 PF00069 0.632
MOD_PKA_2 143 149 PF00069 0.627
MOD_PKA_2 300 306 PF00069 0.688
MOD_PKA_2 401 407 PF00069 0.664
MOD_PKA_2 691 697 PF00069 0.484
MOD_PKA_2 810 816 PF00069 0.513
MOD_PKB_1 577 585 PF00069 0.516
MOD_Plk_1 158 164 PF00069 0.706
MOD_Plk_1 51 57 PF00069 0.385
MOD_Plk_1 640 646 PF00069 0.493
MOD_Plk_1 819 825 PF00069 0.443
MOD_Plk_1 862 868 PF00069 0.484
MOD_Plk_4 158 164 PF00069 0.666
MOD_Plk_4 194 200 PF00069 0.700
MOD_Plk_4 387 393 PF00069 0.637
MOD_Plk_4 456 462 PF00069 0.620
MOD_Plk_4 497 503 PF00069 0.472
MOD_Plk_4 513 519 PF00069 0.542
MOD_Plk_4 640 646 PF00069 0.607
MOD_Plk_4 659 665 PF00069 0.438
MOD_Plk_4 761 767 PF00069 0.484
MOD_ProDKin_1 354 360 PF00069 0.735
MOD_ProDKin_1 453 459 PF00069 0.639
MOD_ProDKin_1 540 546 PF00069 0.572
MOD_ProDKin_1 549 555 PF00069 0.486
MOD_ProDKin_1 796 802 PF00069 0.484
MOD_SUMO_rev_2 121 130 PF00179 0.649
MOD_SUMO_rev_2 668 673 PF00179 0.553
TRG_DiLeu_BaEn_1 481 486 PF01217 0.681
TRG_DiLeu_BaEn_1 640 645 PF01217 0.553
TRG_DiLeu_BaEn_2 193 199 PF01217 0.702
TRG_DiLeu_BaEn_2 220 226 PF01217 0.632
TRG_DiLeu_BaLyEn_6 129 134 PF01217 0.684
TRG_DiLeu_BaLyEn_6 23 28 PF01217 0.441
TRG_DiLeu_BaLyEn_6 447 452 PF01217 0.696
TRG_DiLeu_BaLyEn_6 96 101 PF01217 0.694
TRG_ENDOCYTIC_2 397 400 PF00928 0.658
TRG_ENDOCYTIC_2 403 406 PF00928 0.656
TRG_ENDOCYTIC_2 421 424 PF00928 0.610
TRG_ENDOCYTIC_2 508 511 PF00928 0.583
TRG_ENDOCYTIC_2 531 534 PF00928 0.505
TRG_ENDOCYTIC_2 631 634 PF00928 0.494
TRG_ENDOCYTIC_2 709 712 PF00928 0.489
TRG_ENDOCYTIC_2 733 736 PF00928 0.533
TRG_ENDOCYTIC_2 859 862 PF00928 0.459
TRG_ENDOCYTIC_2 881 884 PF00928 0.553
TRG_ER_diArg_1 130 132 PF00400 0.703
TRG_ER_diArg_1 152 155 PF00400 0.646
TRG_ER_diArg_1 156 158 PF00400 0.648
TRG_ER_diArg_1 328 331 PF00400 0.718
TRG_ER_diArg_1 332 334 PF00400 0.715
TRG_ER_diArg_1 400 402 PF00400 0.652
TRG_ER_diArg_1 576 579 PF00400 0.490
TRG_ER_diArg_1 613 616 PF00400 0.485
TRG_ER_diArg_1 664 666 PF00400 0.575
TRG_ER_diArg_1 831 834 PF00400 0.487
TRG_Pf-PMV_PEXEL_1 132 137 PF00026 0.445
TRG_Pf-PMV_PEXEL_1 665 669 PF00026 0.314

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2W0 Leptomonas seymouri 53% 94%
A4H3C0 Leishmania braziliensis 75% 100%
A4HRS4 Leishmania infantum 100% 100%
E9AC99 Leishmania major 92% 100%
E9AJI7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS