COX assembly mitochondrial protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H4U2_LEIDO

TriTrypDb:

LdBPK_010290.1 , LdCL_010007900 , LDHU3_01.0320

Length:

172


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	9
GO:0043226	organelle	2	9
GO:0043227	membrane-bounded organelle	3	9
GO:0043229	intracellular organelle	3	9
GO:0043231	intracellular membrane-bounded organelle	4	9
GO:0110165	cellular anatomical entity	1	9

A0A3S5H4U2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H4U2


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	13	17	PF00656	0.609
CLV_NRD_NRD_1	55	57	PF00675	0.341
CLV_PCSK_KEX2_1	118	120	PF00082	0.654
CLV_PCSK_PC1ET2_1	118	120	PF00082	0.654
CLV_PCSK_PC7_1	114	120	PF00082	0.535
CLV_PCSK_SKI1_1	57	61	PF00082	0.402
CLV_Separin_Metazoa	111	115	PF03568	0.531
DOC_PP1_RVXF_1	55	62	PF00149	0.420
DOC_WW_Pin1_4	27	32	PF00397	0.609
LIG_14-3-3_CanoR_1	56	62	PF00244	0.456
LIG_BIR_II_1	1	5	PF00653	0.630
LIG_eIF4E_1	107	113	PF01652	0.593
LIG_FHA_2	162	168	PF00498	0.738
LIG_FHA_2	28	34	PF00498	0.719
LIG_LIR_Nem_3	97	103	PF02991	0.355
LIG_PCNA_yPIPBox_3	20	29	PF02747	0.613
LIG_Pex14_1	138	142	PF04695	0.609
LIG_SH2_STAP1	65	69	PF00017	0.355
LIG_SH2_STAT5	107	110	PF00017	0.566
LIG_SH3_3	126	132	PF00018	0.607
LIG_TRAF2_1	164	167	PF00917	0.767
LIG_UBA3_1	46	51	PF00899	0.335
MOD_CK2_1	161	167	PF00069	0.729
MOD_CK2_1	27	33	PF00069	0.714
MOD_GSK3_1	161	168	PF00069	0.727
MOD_N-GLC_2	88	90	PF02516	0.335
MOD_PIKK_1	68	74	PF00454	0.447
MOD_Plk_1	15	21	PF00069	0.720
MOD_ProDKin_1	27	33	PF00069	0.611
MOD_SUMO_for_1	50	53	PF00179	0.355
TRG_ENDOCYTIC_2	103	106	PF00928	0.586
TRG_ENDOCYTIC_2	146	149	PF00928	0.566


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCP6	Leptomonas seymouri	86%	100%
A0A0S4J3U9	Bodo saltans	64%	100%
A0A1X0P3F2	Trypanosomatidae	68%	100%
A0A3R7LAI1	Trypanosoma rangeli	67%	100%
A4H353	Leishmania braziliensis	92%	100%
A4HRF0	Leishmania infantum	100%	100%
C9ZXE7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
E9AC18	Leishmania major	94%	100%
E9AJB5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%