LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S5H4T9_LEIDO
TriTrypDb:
LdCL_010007300 , LDHU3_01.0260
Length:
138

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3S5H4T9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H4T9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_Separin_Metazoa 77 81 PF03568 0.640
DEG_MDM2_SWIB_1 51 58 PF02201 0.570
DEG_Nend_Nbox_1 1 3 PF02207 0.627
DOC_MAPK_MEF2A_6 3 10 PF00069 0.539
DOC_PP4_FxxP_1 62 65 PF00568 0.668
LIG_14-3-3_CanoR_1 120 124 PF00244 0.585
LIG_BRCT_BRCA1_1 47 51 PF00533 0.644
LIG_FHA_1 20 26 PF00498 0.580
LIG_FHA_1 70 76 PF00498 0.544
LIG_FHA_2 68 74 PF00498 0.616
LIG_LIR_Apic_2 19 24 PF02991 0.539
LIG_LIR_Apic_2 61 65 PF02991 0.725
LIG_LIR_Nem_3 22 26 PF02991 0.639
LIG_LIR_Nem_3 48 54 PF02991 0.569
LIG_LYPXL_yS_3 23 26 PF13949 0.549
LIG_Pex14_2 51 55 PF04695 0.663
LIG_SH2_CRK 121 125 PF00017 0.554
LIG_SH2_CRK 21 25 PF00017 0.566
LIG_SH2_STAT5 110 113 PF00017 0.541
LIG_SH2_STAT5 21 24 PF00017 0.582
LIG_SUMO_SIM_anti_2 91 96 PF11976 0.577
LIG_SUMO_SIM_par_1 87 93 PF11976 0.488
MOD_CK1_1 105 111 PF00069 0.655
MOD_CK1_1 45 51 PF00069 0.547
MOD_GlcNHglycan 104 107 PF01048 0.702
MOD_GlcNHglycan 47 50 PF01048 0.584
MOD_GlcNHglycan 51 54 PF01048 0.607
MOD_GlcNHglycan 86 89 PF01048 0.490
MOD_GlcNHglycan 95 98 PF01048 0.575
MOD_GSK3_1 28 35 PF00069 0.613
MOD_GSK3_1 38 45 PF00069 0.539
MOD_GSK3_1 54 61 PF00069 0.666
MOD_GSK3_1 84 91 PF00069 0.472
MOD_N-GLC_1 129 134 PF02516 0.652
MOD_NEK2_1 1 6 PF00069 0.562
MOD_NEK2_1 102 107 PF00069 0.497
MOD_NEK2_1 16 21 PF00069 0.525
MOD_NEK2_1 54 59 PF00069 0.659
MOD_NEK2_1 78 83 PF00069 0.531
MOD_NEK2_1 90 95 PF00069 0.515
MOD_PIKK_1 16 22 PF00454 0.541
MOD_PKA_2 119 125 PF00069 0.639
MOD_PKB_1 127 135 PF00069 0.579
MOD_Plk_1 67 73 PF00069 0.574
MOD_Plk_4 105 111 PF00069 0.621
MOD_Plk_4 119 125 PF00069 0.528
MOD_Plk_4 90 96 PF00069 0.518
TRG_ENDOCYTIC_2 121 124 PF00928 0.549
TRG_ENDOCYTIC_2 23 26 PF00928 0.570
TRG_ENDOCYTIC_2 27 30 PF00928 0.588

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6P0 Leptomonas seymouri 50% 100%
A4H348 Leishmania braziliensis 80% 100%
E9AC12 Leishmania major 91% 100%
E9AJA9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS