Rhodanese domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IW55_LEIDO

TriTrypDb:

LdBPK_363290.1 , LdCL_360039600 , LDHU3_36.4530

Length:

249

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IW55

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IW55

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	119	121	PF00675	0.627
CLV_PCSK_KEX2_1	119	121	PF00082	0.611
CLV_PCSK_KEX2_1	73	75	PF00082	0.625
CLV_PCSK_PC1ET2_1	73	75	PF00082	0.660
CLV_PCSK_SKI1_1	11	15	PF00082	0.628
CLV_PCSK_SKI1_1	206	210	PF00082	0.653
DEG_SPOP_SBC_1	25	29	PF00917	0.709
DOC_MAPK_JIP1_4	37	43	PF00069	0.534
DOC_USP7_MATH_1	79	83	PF00917	0.682
DOC_USP7_MATH_1	9	13	PF00917	0.575
DOC_USP7_MATH_1	96	100	PF00917	0.580
DOC_WW_Pin1_4	161	166	PF00397	0.706
DOC_WW_Pin1_4	97	102	PF00397	0.660
LIG_14-3-3_CanoR_1	111	117	PF00244	0.565
LIG_14-3-3_CanoR_1	179	188	PF00244	0.658
LIG_14-3-3_CanoR_1	37	42	PF00244	0.710
LIG_14-3-3_CanoR_1	44	52	PF00244	0.652
LIG_14-3-3_CanoR_1	60	68	PF00244	0.682
LIG_BIR_II_1	1	5	PF00653	0.641
LIG_BIR_III_2	162	166	PF00653	0.661
LIG_BRCT_BRCA1_1	135	139	PF00533	0.679
LIG_BRCT_BRCA1_1	163	167	PF00533	0.676
LIG_BRCT_BRCA1_1	39	43	PF00533	0.749
LIG_deltaCOP1_diTrp_1	201	205	PF00928	0.574
LIG_deltaCOP1_diTrp_1	211	217	PF00928	0.586
LIG_FHA_1	108	114	PF00498	0.674
LIG_FHA_1	150	156	PF00498	0.673
LIG_FHA_2	171	177	PF00498	0.597
LIG_FHA_2	234	240	PF00498	0.731
LIG_LIR_Gen_1	211	219	PF02991	0.665
LIG_LIR_Gen_1	64	75	PF02991	0.631
LIG_LIR_Nem_3	136	142	PF02991	0.671
LIG_LIR_Nem_3	164	170	PF02991	0.727
LIG_LIR_Nem_3	203	208	PF02991	0.625
LIG_LIR_Nem_3	211	217	PF02991	0.667
LIG_LIR_Nem_3	64	70	PF02991	0.634
LIG_MYND_1	241	245	PF01753	0.494
LIG_PDZ_Class_3	244	249	PF00595	0.680
LIG_SH2_PTP2	67	70	PF00017	0.629
LIG_SH2_STAP1	170	174	PF00017	0.579
LIG_SH2_STAT5	116	119	PF00017	0.616
LIG_SH2_STAT5	199	202	PF00017	0.724
LIG_SH2_STAT5	67	70	PF00017	0.629
LIG_SH3_3	162	168	PF00018	0.609
LIG_SH3_3	99	105	PF00018	0.653
LIG_SUMO_SIM_anti_2	66	72	PF11976	0.650
LIG_SUMO_SIM_par_1	145	153	PF11976	0.678
LIG_TRAF2_1	236	239	PF00917	0.691
MOD_CK1_1	100	106	PF00069	0.684
MOD_CK1_1	107	113	PF00069	0.664
MOD_CK1_1	134	140	PF00069	0.659
MOD_CK1_1	29	35	PF00069	0.705
MOD_CK1_1	3	9	PF00069	0.675
MOD_CK1_1	42	48	PF00069	0.691
MOD_CK2_1	170	176	PF00069	0.604
MOD_CK2_1	215	221	PF00069	0.638
MOD_CK2_1	232	238	PF00069	0.600
MOD_CK2_1	42	48	PF00069	0.533
MOD_CMANNOS	202	205	PF00535	0.572
MOD_GlcNHglycan	102	105	PF01048	0.614
MOD_GlcNHglycan	217	220	PF01048	0.630
MOD_GlcNHglycan	44	47	PF01048	0.753
MOD_GlcNHglycan	75	78	PF01048	0.597
MOD_GSK3_1	127	134	PF00069	0.756
MOD_GSK3_1	24	31	PF00069	0.714
MOD_GSK3_1	59	66	PF00069	0.725
MOD_GSK3_1	96	103	PF00069	0.659
MOD_NEK2_1	112	117	PF00069	0.578
MOD_NEK2_1	149	154	PF00069	0.705
MOD_NEK2_1	232	237	PF00069	0.654
MOD_NEK2_2	79	84	PF00069	0.712
MOD_PIKK_1	134	140	PF00454	0.659
MOD_PIKK_1	3	9	PF00454	0.675
MOD_PKA_1	73	79	PF00069	0.701
MOD_PKA_2	36	42	PF00069	0.740
MOD_PKA_2	59	65	PF00069	0.701
MOD_PKA_2	73	79	PF00069	0.647
MOD_PKB_1	22	30	PF00069	0.629
MOD_Plk_4	112	118	PF00069	0.588
MOD_Plk_4	63	69	PF00069	0.637
MOD_Plk_4	9	15	PF00069	0.625
MOD_ProDKin_1	161	167	PF00069	0.711
MOD_ProDKin_1	97	103	PF00069	0.659
TRG_DiLeu_BaEn_4	238	244	PF01217	0.635
TRG_DiLeu_BaLyEn_6	108	113	PF01217	0.589
TRG_DiLeu_BaLyEn_6	144	149	PF01217	0.740
TRG_DiLeu_BaLyEn_6	223	228	PF01217	0.686
TRG_ENDOCYTIC_2	67	70	PF00928	0.629
TRG_ER_diArg_1	21	24	PF00400	0.532
TRG_NLS_MonoExtN_4	105	112	PF00514	0.630
TRG_Pf-PMV_PEXEL_1	226	230	PF00026	0.708

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1D7	Leptomonas seymouri	48%	100%
A0A3R7NG27	Trypanosoma rangeli	32%	100%
A4HPI0	Leishmania braziliensis	81%	100%
A4IDA2	Leishmania infantum	100%	100%
E9AT92	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q1A5	Leishmania major	92%	100%
V5DA52	Trypanosoma cruzi	28%	100%