Flagellar_C1a_complex_subunit_C1a-32_putative/Pfa m:PF14769

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Flagellar C1a complex subunit C1a-32, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IVT9_LEIDO

TriTrypDb:

LdBPK_361100.1 , LdCL_360016100 , LDHU3_36.1440

Length:

286

Annotations

Annotations by Jardim et al.

Flagella, Flagellar C1a complex subunit C1a-32

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	4
GO:0031514	motile cilium	5	4
GO:0042995	cell projection	2	4
GO:0043226	organelle	2	4
GO:0043227	membrane-bounded organelle	3	4
GO:0110165	cellular anatomical entity	1	5
GO:0120025	plasma membrane bounded cell projection	3	4
GO:0005930	axoneme	2	1

Expansion

Sequence features

A0A3Q8IVT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IVT9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	17	21	PF00656	0.523
CLV_NRD_NRD_1	284	286	PF00675	0.563
CLV_PCSK_KEX2_1	284	286	PF00082	0.563
CLV_PCSK_KEX2_1	32	34	PF00082	0.441
CLV_PCSK_PC1ET2_1	284	286	PF00082	0.581
CLV_PCSK_PC1ET2_1	32	34	PF00082	0.441
CLV_PCSK_PC7_1	28	34	PF00082	0.433
CLV_PCSK_PC7_1	280	286	PF00082	0.550
CLV_PCSK_SKI1_1	48	52	PF00082	0.354
DEG_APCC_DBOX_1	232	240	PF00400	0.385
DOC_MAPK_MEF2A_6	48	57	PF00069	0.449
DOC_USP7_MATH_1	268	272	PF00917	0.565
DOC_USP7_MATH_1	67	71	PF00917	0.334
DOC_USP7_MATH_2	153	159	PF00917	0.390
DOC_USP7_UBL2_3	190	194	PF12436	0.410
DOC_WW_Pin1_4	70	75	PF00397	0.323
LIG_14-3-3_CanoR_1	111	115	PF00244	0.308
LIG_14-3-3_CanoR_1	116	126	PF00244	0.233
LIG_14-3-3_CanoR_1	218	224	PF00244	0.637
LIG_14-3-3_CanoR_1	48	57	PF00244	0.331
LIG_14-3-3_CanoR_1	98	103	PF00244	0.278
LIG_Actin_WH2_2	145	162	PF00022	0.386
LIG_Actin_WH2_2	15	30	PF00022	0.409
LIG_BIR_II_1	1	5	PF00653	0.377
LIG_BRCT_BRCA1_1	77	81	PF00533	0.368
LIG_DLG_GKlike_1	98	105	PF00625	0.335
LIG_eIF4E_1	60	66	PF01652	0.386
LIG_FHA_1	159	165	PF00498	0.576
LIG_FHA_1	4	10	PF00498	0.361
LIG_FHA_1	75	81	PF00498	0.386
LIG_FHA_2	195	201	PF00498	0.489
LIG_FHA_2	257	263	PF00498	0.540
LIG_LIR_Gen_1	101	110	PF02991	0.259
LIG_LIR_Gen_1	6	11	PF02991	0.463
LIG_LIR_LC3C_4	107	110	PF02991	0.306
LIG_LIR_Nem_3	138	144	PF02991	0.288
LIG_LIR_Nem_3	58	63	PF02991	0.399
LIG_LIR_Nem_3	6	10	PF02991	0.320
LIG_LIR_Nem_3	70	75	PF02991	0.355
LIG_LIR_Nem_3	78	84	PF02991	0.120
LIG_LIR_Nem_3	97	102	PF02991	0.259
LIG_PTB_Apo_2	222	229	PF02174	0.484
LIG_RPA_C_Fungi	222	234	PF08784	0.405
LIG_SH2_CRK	102	106	PF00017	0.335
LIG_SH2_CRK	149	153	PF00017	0.308
LIG_SH2_STAP1	119	123	PF00017	0.412
LIG_SH2_STAT5	147	150	PF00017	0.278
LIG_SH3_3	111	117	PF00018	0.241
LIG_SH3_3	170	176	PF00018	0.474
LIG_SUMO_SIM_anti_2	247	256	PF11976	0.494
LIG_SUMO_SIM_par_1	160	167	PF11976	0.492
LIG_TRAF2_1	197	200	PF00917	0.444
MOD_CDC14_SPxK_1	73	76	PF00782	0.289
MOD_CDK_SPxK_1	70	76	PF00069	0.289
MOD_CK1_1	158	164	PF00069	0.424
MOD_CK1_1	244	250	PF00069	0.477
MOD_CK1_1	270	276	PF00069	0.650
MOD_CK1_1	279	285	PF00069	0.685
MOD_CK1_1	46	52	PF00069	0.469
MOD_CK1_1	70	76	PF00069	0.386
MOD_CK2_1	194	200	PF00069	0.449
MOD_CK2_1	256	262	PF00069	0.535
MOD_GlcNHglycan	178	181	PF01048	0.583
MOD_GlcNHglycan	270	273	PF01048	0.605
MOD_GSK3_1	131	138	PF00069	0.349
MOD_GSK3_1	207	214	PF00069	0.530
MOD_GSK3_1	219	226	PF00069	0.607
MOD_GSK3_1	241	248	PF00069	0.537
MOD_GSK3_1	268	275	PF00069	0.621
MOD_GSK3_1	276	283	PF00069	0.665
MOD_GSK3_1	42	49	PF00069	0.493
MOD_GSK3_1	70	77	PF00069	0.273
MOD_GSK3_1	94	101	PF00069	0.320
MOD_N-GLC_1	164	169	PF02516	0.519
MOD_NEK2_1	136	141	PF00069	0.208
MOD_NEK2_1	223	228	PF00069	0.538
MOD_NEK2_1	75	80	PF00069	0.307
MOD_PIKK_1	48	54	PF00454	0.340
MOD_PIKK_1	67	73	PF00454	0.341
MOD_PKA_2	110	116	PF00069	0.440
MOD_PKA_2	12	18	PF00069	0.513
MOD_PKA_2	279	285	PF00069	0.601
MOD_PKA_2	94	100	PF00069	0.292
MOD_PKB_1	274	282	PF00069	0.602
MOD_Plk_1	223	229	PF00069	0.679
MOD_Plk_1	88	94	PF00069	0.335
MOD_Plk_4	118	124	PF00069	0.413
MOD_Plk_4	131	137	PF00069	0.275
MOD_Plk_4	76	82	PF00069	0.256
MOD_ProDKin_1	70	76	PF00069	0.323
MOD_SUMO_rev_2	249	259	PF00179	0.467
TRG_DiLeu_BaEn_1	249	254	PF01217	0.380
TRG_ENDOCYTIC_2	102	105	PF00928	0.241
TRG_ENDOCYTIC_2	119	122	PF00928	0.374
TRG_ENDOCYTIC_2	149	152	PF00928	0.324
TRG_ENDOCYTIC_2	60	63	PF00928	0.384
TRG_Pf-PMV_PEXEL_1	196	200	PF00026	0.544

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE82	Leptomonas seymouri	70%	100%
A0A0S4JAR9	Bodo saltans	33%	95%
A0A1X0P8D5	Trypanosomatidae	43%	100%
A0A3R7MW02	Trypanosoma rangeli	42%	100%
A1A4V9	Homo sapiens	25%	86%
A4HNW4	Leishmania braziliensis	84%	100%
A4ICN0	Leishmania infantum	100%	100%
D0A2T2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
E9ASM4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4Q1X2	Leishmania major	97%	100%
V5BQE4	Trypanosoma cruzi	45%	100%