Pseudouridine synthase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IUI3_LEIDO

TriTrypDb:

LdCL_340018500 , LDHU3_34.1980

Length:

179

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IUI3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IUI3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	106	108	PF00675	0.722
CLV_NRD_NRD_1	116	118	PF00675	0.611
CLV_NRD_NRD_1	140	142	PF00675	0.525
CLV_NRD_NRD_1	150	152	PF00675	0.467
CLV_NRD_NRD_1	166	168	PF00675	0.466
CLV_NRD_NRD_1	23	25	PF00675	0.548
CLV_NRD_NRD_1	79	81	PF00675	0.561
CLV_NRD_NRD_1	88	90	PF00675	0.578
CLV_PCSK_FUR_1	114	118	PF00082	0.553
CLV_PCSK_FUR_1	148	152	PF00082	0.551
CLV_PCSK_FUR_1	164	168	PF00082	0.462
CLV_PCSK_KEX2_1	105	107	PF00082	0.719
CLV_PCSK_KEX2_1	114	116	PF00082	0.590
CLV_PCSK_KEX2_1	140	142	PF00082	0.525
CLV_PCSK_KEX2_1	148	150	PF00082	0.501
CLV_PCSK_KEX2_1	166	168	PF00082	0.431
CLV_PCSK_KEX2_1	22	24	PF00082	0.542
CLV_PCSK_KEX2_1	78	80	PF00082	0.552
CLV_PCSK_KEX2_1	87	89	PF00082	0.565
CLV_PCSK_PC7_1	111	117	PF00082	0.528
CLV_PCSK_PC7_1	162	168	PF00082	0.455
CLV_PCSK_SKI1_1	117	121	PF00082	0.558
CLV_PCSK_SKI1_1	141	145	PF00082	0.514
CLV_PCSK_SKI1_1	167	171	PF00082	0.490
DEG_Nend_UBRbox_2	1	3	PF02207	0.479
DOC_USP7_MATH_1	57	61	PF00917	0.524
LIG_14-3-3_CanoR_1	141	147	PF00244	0.533
LIG_14-3-3_CanoR_1	89	95	PF00244	0.496
LIG_BRCT_BRCA1_1	97	101	PF00533	0.547
MOD_CK1_1	168	174	PF00069	0.550
MOD_CK1_1	30	36	PF00069	0.505
MOD_CK1_1	62	68	PF00069	0.569
MOD_CK1_1	95	101	PF00069	0.757
MOD_CK2_1	150	156	PF00069	0.474
MOD_Cter_Amidation	112	115	PF01082	0.493
MOD_Cter_Amidation	76	79	PF01082	0.552
MOD_Cter_Amidation	85	88	PF01082	0.495
MOD_GlcNHglycan	144	147	PF01048	0.564
MOD_GlcNHglycan	152	155	PF01048	0.497
MOD_GlcNHglycan	167	170	PF01048	0.596
MOD_GlcNHglycan	29	32	PF01048	0.577
MOD_GlcNHglycan	55	58	PF01048	0.544
MOD_GlcNHglycan	64	67	PF01048	0.526
MOD_GlcNHglycan	68	71	PF01048	0.507
MOD_GlcNHglycan	75	78	PF01048	0.450
MOD_GlcNHglycan	94	97	PF01048	0.561
MOD_GSK3_1	53	60	PF00069	0.745
MOD_GSK3_1	62	69	PF00069	0.619
MOD_GSK3_1	97	104	PF00069	0.596
MOD_N-GLC_1	43	48	PF02516	0.522
MOD_N-GLC_1	53	58	PF02516	0.535
MOD_NEK2_1	101	106	PF00069	0.675
MOD_NEK2_1	170	175	PF00069	0.534
MOD_PIKK_1	25	31	PF00454	0.662
MOD_PIKK_1	43	49	PF00454	0.556
MOD_PKA_1	150	156	PF00069	0.457
MOD_PKA_2	150	156	PF00069	0.538
MOD_PKA_2	165	171	PF00069	0.466
MOD_PKA_2	25	31	PF00069	0.496
MOD_PKA_2	62	68	PF00069	0.569
MOD_PKB_1	148	156	PF00069	0.468
MOD_PKB_1	78	86	PF00069	0.561
MOD_SUMO_rev_2	30	39	PF00179	0.562
MOD_SUMO_rev_2	9	17	PF00179	0.487
TRG_ER_diArg_1	105	107	PF00400	0.721
TRG_ER_diArg_1	114	117	PF00400	0.602
TRG_ER_diArg_1	147	150	PF00400	0.681
TRG_ER_diArg_1	172	175	PF00400	0.570
TRG_ER_diArg_1	21	24	PF00400	0.538
TRG_ER_diArg_1	78	80	PF00400	0.563
TRG_ER_diArg_1	87	89	PF00400	0.599
TRG_Pf-PMV_PEXEL_1	106	110	PF00026	0.540
TRG_Pf-PMV_PEXEL_1	6	10	PF00026	0.421

Homologs


Protein	Taxonomy	Sequence identity	Coverage
C9ZMV2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%