Complex 1 protein (LYR family), putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Complex 1 protein (LYR family), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IU86_LEIDO

TriTrypDb:

LdBPK_332850.1 , LdCL_330035600 , LDHU3_33.3990

Length:

166

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IU86

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IU86

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	110	114	PF00656	0.754
CLV_NRD_NRD_1	107	109	PF00675	0.709
CLV_NRD_NRD_1	59	61	PF00675	0.419
CLV_PCSK_KEX2_1	107	109	PF00082	0.694
CLV_PCSK_KEX2_1	163	165	PF00082	0.623
CLV_PCSK_KEX2_1	74	76	PF00082	0.350
CLV_PCSK_KEX2_1	88	90	PF00082	0.285
CLV_PCSK_PC1ET2_1	74	76	PF00082	0.422
CLV_PCSK_PC1ET2_1	88	90	PF00082	0.241
CLV_PCSK_SKI1_1	45	49	PF00082	0.355
CLV_PCSK_SKI1_1	61	65	PF00082	0.447
CLV_PCSK_SKI1_1	98	102	PF00082	0.498
DEG_APCC_DBOX_1	44	52	PF00400	0.355
DEG_Nend_Nbox_1	1	3	PF02207	0.609
DOC_CYCLIN_RxL_1	95	105	PF00134	0.600
DOC_MAPK_gen_1	88	96	PF00069	0.453
DOC_PP1_RVXF_1	59	66	PF00149	0.447
DOC_USP7_MATH_1	145	149	PF00917	0.689
DOC_WW_Pin1_4	6	11	PF00397	0.734
LIG_deltaCOP1_diTrp_1	120	126	PF00928	0.600
LIG_FHA_1	155	161	PF00498	0.594
LIG_FHA_1	38	44	PF00498	0.408
LIG_FHA_2	108	114	PF00498	0.752
LIG_FHA_2	119	125	PF00498	0.469
LIG_LIR_Gen_1	120	129	PF02991	0.522
LIG_LIR_Nem_3	120	126	PF02991	0.517
LIG_LIR_Nem_3	29	33	PF02991	0.470
LIG_NRP_CendR_1	163	166	PF00754	0.669
LIG_SH2_STAP1	140	144	PF00017	0.702
LIG_SH2_STAT3	151	154	PF00017	0.622
LIG_SH2_STAT3	35	38	PF00017	0.527
LIG_SH2_STAT5	151	154	PF00017	0.646
LIG_SH2_STAT5	42	45	PF00017	0.438
LIG_WRC_WIRS_1	27	32	PF05994	0.475
MOD_CDK_SPK_2	6	11	PF00069	0.656
MOD_CK1_1	118	124	PF00069	0.634
MOD_CK1_1	147	153	PF00069	0.689
MOD_CK1_1	29	35	PF00069	0.552
MOD_GlcNHglycan	129	132	PF01048	0.566
MOD_GlcNHglycan	147	150	PF01048	0.692
MOD_GlcNHglycan	83	86	PF01048	0.388
MOD_GSK3_1	140	147	PF00069	0.615
MOD_GSK3_1	150	157	PF00069	0.637
MOD_NEK2_2	37	42	PF00069	0.495
MOD_PIKK_1	150	156	PF00454	0.623
MOD_PKA_1	107	113	PF00069	0.700
MOD_PKA_2	107	113	PF00069	0.700
MOD_Plk_1	140	146	PF00069	0.704
MOD_Plk_4	118	124	PF00069	0.618
MOD_Plk_4	147	153	PF00069	0.691
MOD_Plk_4	37	43	PF00069	0.422
MOD_ProDKin_1	6	12	PF00069	0.735
MOD_SUMO_rev_2	58	63	PF00179	0.480
TRG_DiLeu_BaEn_1	59	64	PF01217	0.355
TRG_ENDOCYTIC_2	44	47	PF00928	0.330
TRG_ER_diArg_1	106	108	PF00400	0.603
TRG_ER_diArg_1	163	166	PF00400	0.670
TRG_ER_diArg_1	65	68	PF00400	0.350
TRG_Pf-PMV_PEXEL_1	98	102	PF00026	0.522

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZD1	Leptomonas seymouri	80%	99%
A0A0S4JQG9	Bodo saltans	45%	92%
A0A1X0NRJ6	Trypanosomatidae	61%	100%
A0A422N9P9	Trypanosoma rangeli	59%	100%
A4HLY2	Leishmania braziliensis	88%	100%
A4I9B1	Leishmania infantum	99%	100%
C9ZJB5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	62%	100%
E9B4B1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4Q3R5	Leishmania major	98%	100%