Sulfite exporter TauE/SafE, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

sulfite exporter TauE/SafE, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IU11_LEIDO

TriTrypDb:

LdBPK_331650.1 , LdCL_330023100 , LDHU3_33.2490

Length:

670

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

Expansion

Sequence features

A0A3Q8IU11

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IU11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	113	117	PF00656	0.329
CLV_NRD_NRD_1	144	146	PF00675	0.396
CLV_NRD_NRD_1	499	501	PF00675	0.549
CLV_NRD_NRD_1	570	572	PF00675	0.614
CLV_NRD_NRD_1	614	616	PF00675	0.525
CLV_PCSK_FUR_1	145	149	PF00082	0.425
CLV_PCSK_KEX2_1	147	149	PF00082	0.423
CLV_PCSK_KEX2_1	461	463	PF00082	0.503
CLV_PCSK_KEX2_1	479	481	PF00082	0.344
CLV_PCSK_KEX2_1	499	501	PF00082	0.353
CLV_PCSK_KEX2_1	570	572	PF00082	0.630
CLV_PCSK_KEX2_1	613	615	PF00082	0.568
CLV_PCSK_PC1ET2_1	147	149	PF00082	0.474
CLV_PCSK_PC1ET2_1	461	463	PF00082	0.503
CLV_PCSK_PC1ET2_1	479	481	PF00082	0.370
CLV_PCSK_SKI1_1	121	125	PF00082	0.517
CLV_PCSK_SKI1_1	156	160	PF00082	0.455
CLV_PCSK_SKI1_1	297	301	PF00082	0.497
CLV_PCSK_SKI1_1	539	543	PF00082	0.594
CLV_PCSK_SKI1_1	607	611	PF00082	0.479
CLV_PCSK_SKI1_1	71	75	PF00082	0.423
CLV_PCSK_SKI1_1	91	95	PF00082	0.171
DEG_SPOP_SBC_1	634	638	PF00917	0.820
DOC_ANK_TNKS_1	198	205	PF00023	0.750
DOC_CKS1_1	618	623	PF01111	0.805
DOC_CYCLIN_RxL_1	119	127	PF00134	0.407
DOC_CYCLIN_RxL_1	68	76	PF00134	0.430
DOC_MAPK_gen_1	154	162	PF00069	0.629
DOC_MAPK_gen_1	469	477	PF00069	0.656
DOC_MAPK_MEF2A_6	154	162	PF00069	0.654
DOC_MAPK_RevD_3	131	147	PF00069	0.432
DOC_PP1_RVXF_1	120	127	PF00149	0.407
DOC_PP1_RVXF_1	358	364	PF00149	0.317
DOC_PP1_RVXF_1	69	75	PF00149	0.376
DOC_PP4_FxxP_1	270	273	PF00568	0.629
DOC_PP4_FxxP_1	352	355	PF00568	0.407
DOC_PP4_FxxP_1	565	568	PF00568	0.685
DOC_PP4_FxxP_1	74	77	PF00568	0.376
DOC_PP4_MxPP_1	198	201	PF00568	0.811
DOC_PP4_MxPP_1	216	219	PF00568	0.646
DOC_USP7_MATH_1	191	195	PF00917	0.762
DOC_USP7_MATH_1	220	224	PF00917	0.802
DOC_USP7_MATH_1	541	545	PF00917	0.822
DOC_USP7_MATH_1	634	638	PF00917	0.820
DOC_USP7_MATH_1	98	102	PF00917	0.423
DOC_USP7_UBL2_3	317	321	PF12436	0.517
DOC_WW_Pin1_4	286	291	PF00397	0.724
DOC_WW_Pin1_4	51	56	PF00397	0.391
DOC_WW_Pin1_4	588	593	PF00397	0.760
DOC_WW_Pin1_4	617	622	PF00397	0.788
DOC_WW_Pin1_4	657	662	PF00397	0.768
DOC_WW_Pin1_4	73	78	PF00397	0.430
LIG_14-3-3_CanoR_1	297	302	PF00244	0.749
LIG_14-3-3_CanoR_1	360	369	PF00244	0.317
LIG_14-3-3_CanoR_1	471	477	PF00244	0.656
LIG_14-3-3_CanoR_1	490	496	PF00244	0.690
LIG_14-3-3_CanoR_1	499	509	PF00244	0.748
LIG_14-3-3_CanoR_1	607	613	PF00244	0.782
LIG_Actin_WH2_2	108	123	PF00022	0.517
LIG_BIR_III_4	311	315	PF00653	0.682
LIG_BRCT_BRCA1_1	47	51	PF00533	0.467
LIG_BRCT_BRCA1_1	561	565	PF00533	0.682
LIG_FHA_1	12	18	PF00498	0.395
LIG_FHA_1	125	131	PF00498	0.379
LIG_FHA_1	175	181	PF00498	0.728
LIG_FHA_1	446	452	PF00498	0.430
LIG_FHA_1	5	11	PF00498	0.649
LIG_FHA_1	504	510	PF00498	0.753
LIG_FHA_1	578	584	PF00498	0.789
LIG_FHA_2	111	117	PF00498	0.537
LIG_FHA_2	241	247	PF00498	0.795
LIG_FHA_2	548	554	PF00498	0.837
LIG_GBD_Chelix_1	326	334	PF00786	0.430
LIG_LIR_Apic_2	213	218	PF02991	0.753
LIG_LIR_Apic_2	268	273	PF02991	0.620
LIG_LIR_Apic_2	562	568	PF02991	0.682
LIG_LIR_Gen_1	298	306	PF02991	0.623
LIG_LIR_Gen_1	383	393	PF02991	0.342
LIG_LIR_Gen_1	417	426	PF02991	0.376
LIG_LIR_Gen_1	503	511	PF02991	0.802
LIG_LIR_LC3C_4	76	80	PF02991	0.430
LIG_LIR_Nem_3	298	304	PF02991	0.624
LIG_LIR_Nem_3	383	389	PF02991	0.309
LIG_LIR_Nem_3	417	421	PF02991	0.426
LIG_LIR_Nem_3	503	508	PF02991	0.798
LIG_LIR_Nem_3	6	12	PF02991	0.524
LIG_MYND_1	286	290	PF01753	0.725
LIG_NRBOX	422	428	PF00104	0.376
LIG_PDZ_Class_1	665	670	PF00595	0.838
LIG_Pex14_1	380	384	PF04695	0.337
LIG_Pex14_2	348	352	PF04695	0.407
LIG_Pex14_2	400	404	PF04695	0.430
LIG_PTB_Apo_2	378	385	PF02174	0.407
LIG_SH2_CRK	215	219	PF00017	0.747
LIG_SH2_CRK	618	622	PF00017	0.833
LIG_SH2_PTP2	12	15	PF00017	0.424
LIG_SH2_PTP2	135	138	PF00017	0.376
LIG_SH2_PTP2	69	72	PF00017	0.430
LIG_SH2_STAT5	112	115	PF00017	0.475
LIG_SH2_STAT5	12	15	PF00017	0.501
LIG_SH2_STAT5	135	138	PF00017	0.376
LIG_SH2_STAT5	357	360	PF00017	0.302
LIG_SH2_STAT5	457	460	PF00017	0.528
LIG_SH2_STAT5	69	72	PF00017	0.376
LIG_SH2_STAT5	81	84	PF00017	0.466
LIG_SH3_3	197	203	PF00018	0.805
LIG_SH3_3	337	343	PF00018	0.342
LIG_SH3_3	572	578	PF00018	0.767
LIG_SUMO_SIM_anti_2	101	108	PF11976	0.410
LIG_SUMO_SIM_par_1	389	394	PF11976	0.371
LIG_SUMO_SIM_par_1	424	430	PF11976	0.348
LIG_TRAF2_1	166	169	PF00917	0.644
LIG_TYR_ITIM	10	15	PF00017	0.501
LIG_TYR_ITIM	110	115	PF00017	0.597
LIG_TYR_ITIM	133	138	PF00017	0.430
LIG_TYR_ITIM	67	72	PF00017	0.376
LIG_TYR_ITIM	79	84	PF00017	0.376
LIG_UBA3_1	427	436	PF00899	0.501
LIG_WRC_WIRS_1	502	507	PF05994	0.794
MOD_CDC14_SPxK_1	294	297	PF00782	0.719
MOD_CDC14_SPxK_1	59	62	PF00782	0.467
MOD_CDK_SPxK_1	286	292	PF00069	0.721
MOD_CDK_SPxK_1	56	62	PF00069	0.474
MOD_CDK_SPxxK_3	657	664	PF00069	0.751
MOD_CK1_1	174	180	PF00069	0.679
MOD_CK1_1	291	297	PF00069	0.690
MOD_CK1_1	364	370	PF00069	0.322
MOD_CK1_1	491	497	PF00069	0.725
MOD_CK1_1	498	504	PF00069	0.725
MOD_CK1_1	623	629	PF00069	0.794
MOD_CK1_1	635	641	PF00069	0.818
MOD_CK1_1	646	652	PF00069	0.842
MOD_CK1_1	662	668	PF00069	0.690
MOD_CK1_1	87	93	PF00069	0.613
MOD_CK2_1	240	246	PF00069	0.739
MOD_CK2_1	470	476	PF00069	0.616
MOD_CK2_1	547	553	PF00069	0.838
MOD_GlcNHglycan	227	230	PF01048	0.542
MOD_GlcNHglycan	322	325	PF01048	0.457
MOD_GlcNHglycan	363	366	PF01048	0.499
MOD_GlcNHglycan	544	547	PF01048	0.612
MOD_GlcNHglycan	601	604	PF01048	0.593
MOD_GlcNHglycan	644	648	PF01048	0.591
MOD_GSK3_1	171	178	PF00069	0.656
MOD_GSK3_1	291	298	PF00069	0.684
MOD_GSK3_1	316	323	PF00069	0.590
MOD_GSK3_1	445	452	PF00069	0.430
MOD_GSK3_1	491	498	PF00069	0.643
MOD_GSK3_1	500	507	PF00069	0.692
MOD_GSK3_1	595	602	PF00069	0.739
MOD_GSK3_1	619	626	PF00069	0.745
MOD_GSK3_1	632	639	PF00069	0.733
MOD_GSK3_1	87	94	PF00069	0.579
MOD_GSK3_1	98	105	PF00069	0.387
MOD_N-GLC_1	191	196	PF02516	0.498
MOD_N-GLC_1	361	366	PF02516	0.517
MOD_N-GLC_1	380	385	PF02516	0.517
MOD_N-GLC_1	45	50	PF02516	0.600
MOD_N-GLC_1	491	496	PF02516	0.473
MOD_N-GLC_1	51	56	PF02516	0.556
MOD_N-GLC_1	623	628	PF02516	0.581
MOD_N-GLC_2	652	654	PF02516	0.585
MOD_NEK2_1	124	129	PF00069	0.371
MOD_NEK2_1	175	180	PF00069	0.657
MOD_NEK2_1	182	187	PF00069	0.648
MOD_NEK2_1	20	25	PF00069	0.426
MOD_NEK2_1	225	230	PF00069	0.819
MOD_NEK2_1	232	237	PF00069	0.712
MOD_NEK2_1	261	266	PF00069	0.664
MOD_NEK2_1	299	304	PF00069	0.650
MOD_NEK2_1	427	432	PF00069	0.325
MOD_NEK2_1	488	493	PF00069	0.718
MOD_NEK2_1	495	500	PF00069	0.700
MOD_NEK2_1	511	516	PF00069	0.737
MOD_NEK2_1	608	613	PF00069	0.796
MOD_NEK2_2	171	176	PF00069	0.669
MOD_NEK2_2	191	196	PF00069	0.649
MOD_PKA_1	570	576	PF00069	0.786
MOD_PKA_2	232	238	PF00069	0.803
MOD_PKA_2	470	476	PF00069	0.659
MOD_PKA_2	498	504	PF00069	0.774
MOD_PKA_2	570	576	PF00069	0.809
MOD_PKB_1	537	545	PF00069	0.762
MOD_Plk_1	191	197	PF00069	0.697
MOD_Plk_1	220	226	PF00069	0.747
MOD_Plk_1	491	497	PF00069	0.679
MOD_Plk_1	84	90	PF00069	0.640
MOD_Plk_4	175	181	PF00069	0.706
MOD_Plk_4	182	188	PF00069	0.675
MOD_Plk_4	191	197	PF00069	0.676
MOD_Plk_4	20	26	PF00069	0.430
MOD_Plk_4	220	226	PF00069	0.794
MOD_Plk_4	233	239	PF00069	0.694
MOD_Plk_4	442	448	PF00069	0.413
MOD_Plk_4	491	497	PF00069	0.687
MOD_Plk_4	5	11	PF00069	0.631
MOD_Plk_4	504	510	PF00069	0.712
MOD_Plk_4	636	642	PF00069	0.787
MOD_Plk_4	84	90	PF00069	0.640
MOD_Plk_4	91	97	PF00069	0.556
MOD_Plk_4	99	105	PF00069	0.430
MOD_ProDKin_1	286	292	PF00069	0.721
MOD_ProDKin_1	51	57	PF00069	0.393
MOD_ProDKin_1	588	594	PF00069	0.760
MOD_ProDKin_1	617	623	PF00069	0.788
MOD_ProDKin_1	657	663	PF00069	0.768
MOD_ProDKin_1	73	79	PF00069	0.430
MOD_SUMO_for_1	557	560	PF00179	0.783
MOD_SUMO_rev_2	151	155	PF00179	0.689
TRG_DiLeu_BaEn_4	168	174	PF01217	0.658
TRG_DiLeu_BaLyEn_6	408	413	PF01217	0.556
TRG_DiLeu_BaLyEn_6	604	609	PF01217	0.682
TRG_DiLeu_BaLyEn_6	68	73	PF01217	0.390
TRG_ENDOCYTIC_2	112	115	PF00928	0.475
TRG_ENDOCYTIC_2	12	15	PF00928	0.501
TRG_ENDOCYTIC_2	135	138	PF00928	0.376
TRG_ENDOCYTIC_2	482	485	PF00928	0.651
TRG_ENDOCYTIC_2	69	72	PF00928	0.376
TRG_ENDOCYTIC_2	81	84	PF00928	0.466
TRG_ER_diArg_1	303	306	PF00400	0.642
TRG_ER_diArg_1	569	571	PF00400	0.791
TRG_ER_diArg_1	612	615	PF00400	0.685
TRG_NLS_MonoCore_2	144	149	PF00514	0.674
TRG_NLS_MonoExtC_3	145	151	PF00514	0.637
TRG_NLS_MonoExtC_3	460	465	PF00514	0.631
TRG_NLS_MonoExtN_4	142	149	PF00514	0.621
TRG_Pf-PMV_PEXEL_1	411	416	PF00026	0.407

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P256	Leptomonas seymouri	38%	100%
A0A0N1HZC1	Leptomonas seymouri	69%	100%
A4HLL6	Leishmania braziliensis	81%	100%
A4I927	Leishmania infantum	100%	100%
E9B3Z2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4Q432	Leishmania major	95%	100%