Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8ITS9_LEIDO

TriTrypDb:

LdBPK_330120.1 , LdCL_330006100 , LDHU3_33.0140

Length:

303

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ITS9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ITS9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	207	211	PF00656	0.639
CLV_C14_Caspase3-7	219	223	PF00656	0.539
CLV_NRD_NRD_1	121	123	PF00675	0.792
CLV_NRD_NRD_1	138	140	PF00675	0.443
CLV_NRD_NRD_1	171	173	PF00675	0.532
CLV_NRD_NRD_1	229	231	PF00675	0.684
CLV_NRD_NRD_1	262	264	PF00675	0.692
CLV_NRD_NRD_1	299	301	PF00675	0.631
CLV_NRD_NRD_1	97	99	PF00675	0.787
CLV_PCSK_KEX2_1	138	140	PF00082	0.560
CLV_PCSK_KEX2_1	171	173	PF00082	0.536
CLV_PCSK_KEX2_1	231	233	PF00082	0.598
CLV_PCSK_KEX2_1	262	264	PF00082	0.692
CLV_PCSK_KEX2_1	299	301	PF00082	0.631
CLV_PCSK_KEX2_1	97	99	PF00082	0.799
CLV_PCSK_PC1ET2_1	231	233	PF00082	0.583
CLV_PCSK_SKI1_1	239	243	PF00082	0.653
CLV_PCSK_SKI1_1	285	289	PF00082	0.549
CLV_PCSK_SKI1_1	98	102	PF00082	0.576
DEG_SPOP_SBC_1	100	104	PF00917	0.692
DOC_MAPK_gen_1	185	193	PF00069	0.474
DOC_PP1_RVXF_1	5	11	PF00149	0.608
DOC_PP2B_LxvP_1	41	44	PF13499	0.602
DOC_USP7_MATH_1	100	104	PF00917	0.692
DOC_USP7_MATH_1	272	276	PF00917	0.629
DOC_WW_Pin1_4	110	115	PF00397	0.797
DOC_WW_Pin1_4	117	122	PF00397	0.712
DOC_WW_Pin1_4	127	132	PF00397	0.588
DOC_WW_Pin1_4	31	36	PF00397	0.708
LIG_14-3-3_CanoR_1	156	162	PF00244	0.518
LIG_14-3-3_CanoR_1	171	177	PF00244	0.355
LIG_14-3-3_CanoR_1	248	254	PF00244	0.639
LIG_14-3-3_CanoR_1	68	77	PF00244	0.639
LIG_FHA_2	158	164	PF00498	0.623
LIG_FHA_2	205	211	PF00498	0.544
LIG_RPA_C_Fungi	160	172	PF08784	0.494
LIG_RPA_C_Fungi	258	270	PF08784	0.637
LIG_SH2_STAT3	159	162	PF00017	0.522
LIG_SH2_STAT5	159	162	PF00017	0.573
LIG_SH3_3	44	50	PF00018	0.650
LIG_SH3_3	54	60	PF00018	0.621
LIG_SH3_3	61	67	PF00018	0.636
LIG_TRAF2_1	160	163	PF00917	0.520
LIG_TRAF2_1	291	294	PF00917	0.672
LIG_TRAF2_1	60	63	PF00917	0.582
LIG_WW_2	64	67	PF00397	0.639
LIG_WW_3	130	134	PF00397	0.638
MOD_CDC14_SPxK_1	120	123	PF00782	0.716
MOD_CDC14_SPxK_1	130	133	PF00782	0.657
MOD_CDK_SPK_2	117	122	PF00069	0.696
MOD_CDK_SPxK_1	117	123	PF00069	0.729
MOD_CDK_SPxK_1	127	133	PF00069	0.622
MOD_CDK_SPxxK_3	110	117	PF00069	0.644
MOD_CK1_1	173	179	PF00069	0.576
MOD_CK1_1	237	243	PF00069	0.684
MOD_CK1_1	26	32	PF00069	0.733
MOD_CK2_1	157	163	PF00069	0.511
MOD_CK2_1	272	278	PF00069	0.668
MOD_Cter_Amidation	297	300	PF01082	0.584
MOD_GlcNHglycan	239	242	PF01048	0.692
MOD_GlcNHglycan	243	246	PF01048	0.704
MOD_GlcNHglycan	25	28	PF01048	0.813
MOD_GlcNHglycan	264	267	PF01048	0.740
MOD_GSK3_1	100	107	PF00069	0.767
MOD_GSK3_1	117	124	PF00069	0.638
MOD_GSK3_1	237	244	PF00069	0.715
MOD_GSK3_1	249	256	PF00069	0.579
MOD_GSK3_1	272	279	PF00069	0.619
MOD_GSK3_1	29	36	PF00069	0.806
MOD_N-GLC_1	10	15	PF02516	0.676
MOD_NEK2_1	10	15	PF00069	0.611
MOD_NEK2_1	157	162	PF00069	0.524
MOD_NEK2_1	204	209	PF00069	0.610
MOD_NEK2_1	37	42	PF00069	0.745
MOD_NEK2_2	121	126	PF00069	0.641
MOD_PIKK_1	170	176	PF00454	0.494
MOD_PIKK_1	71	77	PF00454	0.643
MOD_PK_1	277	283	PF00069	0.574
MOD_PKA_1	262	268	PF00069	0.700
MOD_PKA_2	121	127	PF00069	0.702
MOD_PKA_2	170	176	PF00069	0.494
MOD_PKA_2	262	268	PF00069	0.700
MOD_PKA_2	276	282	PF00069	0.538
MOD_Plk_1	10	16	PF00069	0.669
MOD_Plk_1	277	283	PF00069	0.657
MOD_Plk_1	37	43	PF00069	0.696
MOD_Plk_4	212	218	PF00069	0.548
MOD_Plk_4	220	226	PF00069	0.546
MOD_ProDKin_1	110	116	PF00069	0.795
MOD_ProDKin_1	117	123	PF00069	0.712
MOD_ProDKin_1	127	133	PF00069	0.591
MOD_ProDKin_1	31	37	PF00069	0.709
TRG_ENDOCYTIC_2	187	190	PF00928	0.545
TRG_ER_diArg_1	125	128	PF00400	0.744
TRG_ER_diArg_1	137	139	PF00400	0.532
TRG_ER_diArg_1	170	172	PF00400	0.560
TRG_Pf-PMV_PEXEL_1	290	294	PF00026	0.694

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5B4	Leptomonas seymouri	44%	100%
A4HL48	Leishmania braziliensis	64%	100%
A4I8M7	Leishmania infantum	98%	100%
E9B3I9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%