Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IT10_LEIDO

TriTrypDb:

LdBPK_320350.1 , LdCL_320008400 , LDHU3_32.0430

Length:

893

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IT10

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IT10

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	387	391	PF00656	0.670
CLV_C14_Caspase3-7	46	50	PF00656	0.667
CLV_C14_Caspase3-7	51	55	PF00656	0.696
CLV_NRD_NRD_1	103	105	PF00675	0.597
CLV_NRD_NRD_1	405	407	PF00675	0.640
CLV_NRD_NRD_1	43	45	PF00675	0.590
CLV_NRD_NRD_1	434	436	PF00675	0.566
CLV_NRD_NRD_1	453	455	PF00675	0.305
CLV_NRD_NRD_1	731	733	PF00675	0.802
CLV_NRD_NRD_1	747	749	PF00675	0.612

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P865	Leptomonas seymouri	44%	98%
A0A1X0P7Z7	Trypanosomatidae	25%	94%
A4HK14	Leishmania braziliensis	67%	100%
A4I7J8	Leishmania infantum	99%	100%
D0A0A0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9B2F5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q5Q1	Leishmania major	86%	100%

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