Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ISD3_LEIDO

TriTrypDb:

LdBPK_310270.1 , LdCL_310007800 , LDHU3_31.0330

Length:

163

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ISD3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ISD3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	112	114	PF00675	0.743
CLV_NRD_NRD_1	132	134	PF00675	0.474
CLV_NRD_NRD_1	137	139	PF00675	0.668
CLV_NRD_NRD_1	148	150	PF00675	0.494
CLV_PCSK_FUR_1	135	139	PF00082	0.720
CLV_PCSK_KEX2_1	112	114	PF00082	0.743
CLV_PCSK_KEX2_1	132	134	PF00082	0.474
CLV_PCSK_KEX2_1	137	139	PF00082	0.668
CLV_PCSK_KEX2_1	147	149	PF00082	0.508
CLV_PCSK_PC7_1	133	139	PF00082	0.717
CLV_PCSK_SKI1_1	148	152	PF00082	0.681
DEG_APCC_DBOX_1	111	119	PF00400	0.741
DOC_CYCLIN_RxL_1	146	157	PF00134	0.678
DOC_CYCLIN_yCln2_LP_2	117	120	PF00134	0.668
DOC_MAPK_gen_1	147	153	PF00069	0.681
DOC_PP1_RVXF_1	146	153	PF00149	0.681
DOC_PP2B_LxvP_1	117	120	PF13499	0.742
DOC_USP7_UBL2_3	33	37	PF12436	0.602
LIG_14-3-3_CanoR_1	112	116	PF00244	0.744
LIG_14-3-3_CanoR_1	137	143	PF00244	0.721
LIG_14-3-3_CanoR_1	69	79	PF00244	0.663
LIG_APCC_ABBA_1	5	10	PF00400	0.629
LIG_BRCT_BRCA1_1	19	23	PF00533	0.653
LIG_DCNL_PONY_1	1	4	PF03556	0.668
LIG_LIR_Apic_2	141	145	PF02991	0.703
LIG_LIR_Gen_1	10	17	PF02991	0.526
LIG_LIR_Gen_1	96	105	PF02991	0.664
LIG_LIR_Nem_3	10	14	PF02991	0.532
LIG_LIR_Nem_3	96	101	PF02991	0.675
LIG_MYND_1	3	7	PF01753	0.648
LIG_MYND_3	2	6	PF01753	0.657
LIG_SH2_PTP2	142	145	PF00017	0.697
LIG_SH2_STAT5	142	145	PF00017	0.697
LIG_SH3_3	140	146	PF00018	0.702
LIG_SUMO_SIM_anti_2	12	18	PF11976	0.599
LIG_WRC_WIRS_1	51	56	PF05994	0.714
LIG_WW_3	118	122	PF00397	0.679
LIG_WW_3	144	148	PF00397	0.683
MOD_CK1_1	111	117	PF00069	0.741
MOD_CK1_1	70	76	PF00069	0.575
MOD_CK2_1	81	87	PF00069	0.656
MOD_GlcNHglycan	159	162	PF01048	0.663
MOD_GlcNHglycan	19	22	PF01048	0.696
MOD_GlcNHglycan	73	76	PF01048	0.688
MOD_GlcNHglycan	83	86	PF01048	0.535
MOD_GlcNHglycan	95	98	PF01048	0.520
MOD_GSK3_1	67	74	PF00069	0.677
MOD_GSK3_1	77	84	PF00069	0.618
MOD_NEK2_1	17	22	PF00069	0.622
MOD_NEK2_1	24	29	PF00069	0.532
MOD_NEK2_1	67	72	PF00069	0.679
MOD_NEK2_1	77	82	PF00069	0.522
MOD_OFUCOSY	35	41	PF10250	0.566
MOD_PKA_2	111	117	PF00069	0.741
MOD_PKA_2	157	163	PF00069	0.669
MOD_PKA_2	17	23	PF00069	0.575
MOD_Plk_1	9	15	PF00069	0.610
MOD_SUMO_for_1	36	39	PF00179	0.616
TRG_DiLeu_BaLyEn_6	113	118	PF01217	0.586
TRG_DiLeu_BaLyEn_6	146	151	PF01217	0.681
TRG_ER_diArg_1	132	135	PF00400	0.711
TRG_ER_diArg_1	137	140	PF00400	0.667
TRG_ER_diArg_1	146	149	PF00400	0.519

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I6B8	Leishmania infantum	99%	100%
E9B1H6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	100%