LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IRY7_LEIDO
TriTrypDb:
LdBPK_301720.1 , LdCL_300022500 , LDHU3_30.2400
Length:
123

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IRY7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IRY7

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_APCC_DBOX_1 98 106 PF00400 0.514
DEG_Nend_UBRbox_3 1 3 PF02207 0.648
DOC_CYCLIN_yCln2_LP_2 35 41 PF00134 0.611
DOC_MAPK_DCC_7 60 68 PF00069 0.609
DOC_MAPK_MEF2A_6 60 68 PF00069 0.609
DOC_PP2B_LxvP_1 118 121 PF13499 0.586
DOC_PP2B_LxvP_1 35 38 PF13499 0.610
DOC_PP2B_LxvP_1 66 69 PF13499 0.581
DOC_USP7_MATH_1 67 71 PF00917 0.574
DOC_WW_Pin1_4 47 52 PF00397 0.596
LIG_14-3-3_CanoR_1 20 26 PF00244 0.602
LIG_Dynein_DLC8_1 18 24 PF01221 0.593
LIG_EVH1_1 118 122 PF00568 0.580
LIG_FHA_1 20 26 PF00498 0.602
LIG_FHA_1 30 36 PF00498 0.491
LIG_FHA_2 28 34 PF00498 0.685
LIG_LIR_Gen_1 7 18 PF02991 0.585
LIG_LIR_Nem_3 7 13 PF02991 0.585
LIG_SH2_CRK 116 120 PF00017 0.575
LIG_SH2_NCK_1 10 14 PF00017 0.588
LIG_SH2_NCK_1 116 120 PF00017 0.706
LIG_SH2_STAP1 58 62 PF00017 0.575
LIG_SH2_STAT5 52 55 PF00017 0.690
LIG_SH3_1 116 122 PF00018 0.578
LIG_SH3_1 43 49 PF00018 0.563
LIG_SH3_3 116 122 PF00018 0.661
LIG_SH3_3 43 49 PF00018 0.563
LIG_SH3_3 61 67 PF00018 0.605
LIG_SUMO_SIM_anti_2 11 17 PF11976 0.588
LIG_TRFH_1 116 120 PF08558 0.706
MOD_CK1_1 50 56 PF00069 0.675
MOD_CK2_1 5 11 PF00069 0.596
MOD_GlcNHglycan 7 10 PF01048 0.622
MOD_GSK3_1 19 26 PF00069 0.642
MOD_GSK3_1 50 57 PF00069 0.567
MOD_PIKK_1 19 25 PF00454 0.671
MOD_PIKK_1 27 33 PF00454 0.638
MOD_PKA_2 19 25 PF00069 0.603
MOD_ProDKin_1 47 53 PF00069 0.598
TRG_ENDOCYTIC_2 10 13 PF00928 0.587

Homologs

Protein Taxonomy Sequence identity Coverage
A4HIB5 Leishmania braziliensis 89% 100%
A4I5J9 Leishmania infantum 100% 100%
E9B0U4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
Q4Q7C2 Leishmania major 97% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS