Ribosomal S17 family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S17, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IQV8_LEIDO

TriTrypDb:

LdBPK_282750.1 , LdCL_280032600 , LdCL_280032700 , LDHU3_28.3730 , LDHU3_28.3740

Length:

143

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 40S ribosomal S17

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 7

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	9
GO:0032991	protein-containing complex	1	9
GO:0043226	organelle	2	9
GO:0043228	non-membrane-bounded organelle	3	9
GO:0043229	intracellular organelle	3	9
GO:0043232	intracellular non-membrane-bounded organelle	4	9
GO:0110165	cellular anatomical entity	1	9
GO:1990904	ribonucleoprotein complex	2	9
GO:0005737	cytoplasm	2	1

Expansion

Sequence features

A0A3Q8IQV8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IQV8

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	9
GO:0006518	peptide metabolic process	4	9
GO:0006807	nitrogen compound metabolic process	2	9
GO:0008152	metabolic process	1	9
GO:0009058	biosynthetic process	2	9
GO:0009059	macromolecule biosynthetic process	4	9
GO:0009987	cellular process	1	9
GO:0019538	protein metabolic process	3	9
GO:0034641	cellular nitrogen compound metabolic process	3	9
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	9
GO:0043043	peptide biosynthetic process	5	9
GO:0043170	macromolecule metabolic process	3	9
GO:0043603	amide metabolic process	3	9
GO:0043604	amide biosynthetic process	4	9
GO:0044237	cellular metabolic process	2	9
GO:0044238	primary metabolic process	2	9
GO:0044249	cellular biosynthetic process	3	9
GO:0044260	obsolete cellular macromolecule metabolic process	3	9
GO:0044271	cellular nitrogen compound biosynthetic process	4	9
GO:0071704	organic substance metabolic process	2	9
GO:1901564	organonitrogen compound metabolic process	3	9
GO:1901566	organonitrogen compound biosynthetic process	4	9
GO:1901576	organic substance biosynthetic process	3	9

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	9
GO:0005198	structural molecule activity	1	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	118	120	PF00675	0.467
CLV_NRD_NRD_1	136	138	PF00675	0.676
CLV_NRD_NRD_1	80	82	PF00675	0.365
CLV_PCSK_FUR_1	119	123	PF00082	0.729
CLV_PCSK_FUR_1	78	82	PF00082	0.365
CLV_PCSK_KEX2_1	10	12	PF00082	0.365
CLV_PCSK_KEX2_1	103	105	PF00082	0.296
CLV_PCSK_KEX2_1	118	120	PF00082	0.443
CLV_PCSK_KEX2_1	121	123	PF00082	0.726
CLV_PCSK_KEX2_1	135	137	PF00082	0.674
CLV_PCSK_KEX2_1	32	34	PF00082	0.365
CLV_PCSK_KEX2_1	59	61	PF00082	0.365
CLV_PCSK_KEX2_1	80	82	PF00082	0.365
CLV_PCSK_PC1ET2_1	10	12	PF00082	0.365
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.296
CLV_PCSK_PC1ET2_1	121	123	PF00082	0.739
CLV_PCSK_PC1ET2_1	32	34	PF00082	0.365
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.365
CLV_PCSK_SKI1_1	118	122	PF00082	0.402
CLV_PCSK_SKI1_1	44	48	PF00082	0.387
CLV_PCSK_SKI1_1	7	11	PF00082	0.371
DOC_MAPK_gen_1	32	40	PF00069	0.365
DOC_MAPK_MEF2A_6	32	40	PF00069	0.365
DOC_PP1_RVXF_1	21	27	PF00149	0.506
DOC_USP7_MATH_1	86	90	PF00917	0.365
DOC_USP7_MATH_1	94	98	PF00917	0.365
DOC_USP7_UBL2_3	19	23	PF12436	0.365
DOC_USP7_UBL2_3	3	7	PF12436	0.365
DOC_USP7_UBL2_3	45	49	PF12436	0.365
LIG_14-3-3_CanoR_1	5	10	PF00244	0.365
LIG_14-3-3_CanoR_1	67	72	PF00244	0.388
LIG_FHA_1	4	10	PF00498	0.376
LIG_FHA_1	52	58	PF00498	0.418
LIG_FHA_1	86	92	PF00498	0.457
LIG_FHA_2	37	43	PF00498	0.399
LIG_LIR_Gen_1	18	29	PF02991	0.365
LIG_LIR_Nem_3	18	24	PF02991	0.365
LIG_SH2_CRK	21	25	PF00017	0.502
LIG_SH2_GRB2like	29	32	PF00017	0.365
LIG_SH2_STAP1	53	57	PF00017	0.365
LIG_SH2_STAT5	53	56	PF00017	0.418
MOD_CK1_1	97	103	PF00069	0.469
MOD_CK2_1	36	42	PF00069	0.403
MOD_GlcNHglycan	96	99	PF01048	0.544
MOD_GSK3_1	36	43	PF00069	0.365
MOD_NEK2_1	36	41	PF00069	0.387
MOD_PKA_1	10	16	PF00069	0.400
MOD_PKA_2	10	16	PF00069	0.400
MOD_Plk_1	36	42	PF00069	0.365
MOD_SUMO_rev_2	37	46	PF00179	0.399
TRG_ENDOCYTIC_2	21	24	PF00928	0.544
TRG_ER_diArg_1	117	119	PF00400	0.467
TRG_ER_diArg_1	134	137	PF00400	0.758
TRG_ER_diArg_1	80	82	PF00400	0.365
TRG_NLS_Bipartite_1	32	48	PF00514	0.365
TRG_Pf-PMV_PEXEL_1	33	37	PF00026	0.418

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IMP9	Bodo saltans	74%	100%
A0A1D8PEY9	Candida albicans (strain SC5314 / ATCC MYA-2876)	50%	100%
A0A3R7MP42	Trypanosoma rangeli	75%	100%
A4HGV8	Leishmania braziliensis	91%	100%
A4I3Y8	Leishmania infantum	100%	100%
A5PK63	Bos taurus	57%	100%
D0A958	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	74%	100%
E9B078	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
O01692	Caenorhabditis elegans	54%	100%
O42984	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
P02407	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	100%
P04644	Rattus norvegicus	50%	100%
P08636	Gallus gallus	51%	100%
P08708	Homo sapiens	57%	100%
P14127	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	100%
P17704	Drosophila melanogaster	52%	100%
P27770	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	53%	98%
P42520	Dictyostelium discoideum	50%	100%
P49205	Arabidopsis thaliana	52%	100%
P49215	Solanum lycopersicum	54%	99%
P63273	Canis lupus familiaris	57%	100%
P63274	Cricetulus griseus	57%	100%
P63275	Felis catus	57%	100%
P63276	Mus musculus	57%	100%
Q4MYY1	Theileria parva	56%	100%
Q4Q806	Leishmania major	98%	100%
Q6QAP7	Sus scrofa	57%	100%
Q7ZUB2	Coturnix japonica	51%	100%
Q8SSF9	Encephalitozoon cuniculi (strain GB-M1)	42%	100%
Q90YQ6	Ictalurus punctatus	51%	100%
Q962R2	Spodoptera frugiperda	49%	100%
Q967G1	Theileria annulata	56%	100%
Q9LZ17	Arabidopsis thaliana	59%	100%
Q9P7J6	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
Q9SJ36	Arabidopsis thaliana	59%	100%
Q9SQZ1	Arabidopsis thaliana	60%	100%
Q9U9L1	Anopheles gambiae	50%	100%