40S_ribosomal_protein_S10_putative/GeneDB:LmjF.36.0980/GeneDB:LmjF.36.0990

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S10, putative (fragment)

Species:

Leishmania donovani

UniProt:

A0A3Q8IQL3_LEIDO

TriTrypDb:

LdBPK_361040.1 , LdCL_360015500 , LdCL_360015600 , LDHU3_36.1380 , LDHU3_36.1390

Length:

168

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 40S ribosomal S10

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	7
GO:0043226	organelle	2	7
GO:0043228	non-membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043232	intracellular non-membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7
GO:0015935	small ribosomal subunit	4	1
GO:0022627	cytosolic small ribosomal subunit	5	1
GO:0032991	protein-containing complex	1	1
GO:0044391	ribosomal subunit	3	1
GO:1990904	ribonucleoprotein complex	2	1

Phosphorylation

Promastigote/Amastigote: 157

Expansion

Sequence features

A0A3Q8IQL3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IQL3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0003735	structural constituent of ribosome	2	1
GO:0005198	structural molecule activity	1	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	15	19	PF00082	0.383
CLV_PCSK_SKI1_1	54	58	PF00082	0.443
DOC_ANK_TNKS_1	120	127	PF00023	0.797
DOC_ANK_TNKS_1	128	135	PF00023	0.828
DOC_PP2B_PxIxI_1	44	50	PF00149	0.670
DOC_PP4_FxxP_1	42	45	PF00568	0.583
DOC_USP7_MATH_1	154	158	PF00917	0.754
DOC_USP7_MATH_1	6	10	PF00917	0.583
LIG_14-3-3_CanoR_1	15	23	PF00244	0.583
LIG_BIR_II_1	1	5	PF00653	0.745
LIG_BRCT_BRCA1_1	101	105	PF00533	0.833
LIG_BRCT_BRCA1_2	101	107	PF00533	0.835
LIG_FHA_1	17	23	PF00498	0.619
LIG_FHA_1	32	38	PF00498	0.583
LIG_FHA_1	39	45	PF00498	0.556
LIG_FHA_2	72	78	PF00498	0.583
LIG_LIR_Apic_2	41	45	PF02991	0.582
LIG_LIR_Gen_1	102	110	PF02991	0.609
LIG_LIR_Gen_1	85	94	PF02991	0.623
LIG_LIR_Nem_3	102	108	PF02991	0.608
LIG_LIR_Nem_3	11	17	PF02991	0.570
LIG_LIR_Nem_3	85	89	PF02991	0.623
LIG_Pex14_1	68	72	PF04695	0.583
LIG_SH2_STAT5	4	7	PF00017	0.441
LIG_SH2_STAT5	86	89	PF00017	0.583
LIG_SH3_3	2	8	PF00018	0.490
LIG_UBA3_1	52	57	PF00899	0.583
MOD_CK1_1	55	61	PF00069	0.571
MOD_CK2_1	154	160	PF00069	0.763
MOD_GlcNHglycan	91	94	PF01048	0.418
MOD_GSK3_1	29	36	PF00069	0.583
MOD_GSK3_1	94	101	PF00069	0.670
MOD_NEK2_1	52	57	PF00069	0.571
MOD_PIKK_1	94	100	PF00454	0.678
MOD_PK_1	99	105	PF00069	0.860
TRG_ENDOCYTIC_2	14	17	PF00928	0.583
TRG_ENDOCYTIC_2	72	75	PF00928	0.583
TRG_ENDOCYTIC_2	86	89	PF00928	0.583
TRG_Pf-PMV_PEXEL_1	59	64	PF00026	0.383

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4ICN5	Leishmania infantum	100%	100%
D0A2S5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	62%	77%
D0A2S7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	62%	98%
E9ASL8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
E9ASL9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
O14112	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P46783	Homo sapiens	43%	100%
P63325	Mus musculus	38%	100%
P63326	Rattus norvegicus	38%	100%
Q07254	Xenopus laevis	37%	100%
Q3T0F4	Bos taurus	43%	100%
Q4Q1X7	Leishmania major	99%	100%
Q90YR4	Ictalurus punctatus	37%	100%
Q9LTF2	Arabidopsis thaliana	35%	94%
Q9NQ39	Homo sapiens	38%	95%
Q9SW09	Arabidopsis thaliana	35%	95%