LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IQF9_LEIDO
TriTrypDb:
LdBPK_280920.1 , LdCL_280013800 , LDHU3_28.1100
Length:
176

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IQF9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IQF9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 133 135 PF00675 0.552
CLV_NRD_NRD_1 54 56 PF00675 0.654
CLV_PCSK_KEX2_1 133 135 PF00082 0.501
DEG_Nend_UBRbox_3 1 3 PF02207 0.610
DOC_MAPK_MEF2A_6 148 156 PF00069 0.548
DOC_USP7_MATH_1 81 85 PF00917 0.768
DOC_WW_Pin1_4 94 99 PF00397 0.664
LIG_14-3-3_CanoR_1 148 156 PF00244 0.551
LIG_Actin_WH2_2 25 42 PF00022 0.507
LIG_BIR_III_2 95 99 PF00653 0.787
LIG_LIR_Nem_3 29 34 PF02991 0.453
LIG_LIR_Nem_3 3 9 PF02991 0.679
LIG_RPA_C_Plants 46 57 PF08784 0.539
LIG_SH2_STAT3 21 24 PF00017 0.587
LIG_SH2_STAT5 6 9 PF00017 0.556
LIG_TYR_ITIM 4 9 PF00017 0.549
MOD_CK1_1 155 161 PF00069 0.559
MOD_GlcNHglycan 58 61 PF01048 0.595
MOD_GlcNHglycan 78 81 PF01048 0.716
MOD_N-GLC_2 14 16 PF02516 0.409
MOD_NEK2_1 7 12 PF00069 0.644
MOD_NEK2_2 82 87 PF00069 0.770
MOD_PKA_1 56 62 PF00069 0.558
MOD_PKA_2 147 153 PF00069 0.549
MOD_PKA_2 76 82 PF00069 0.572
MOD_Plk_1 82 88 PF00069 0.654
MOD_ProDKin_1 94 100 PF00069 0.666
TRG_DiLeu_BaEn_2 2 8 PF01217 0.665
TRG_ENDOCYTIC_2 6 9 PF00928 0.546
TRG_Pf-PMV_PEXEL_1 26 30 PF00026 0.451

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PFQ6 Leptomonas seymouri 56% 96%
A4HGC8 Leishmania braziliensis 67% 100%
A4I3G0 Leishmania infantum 100% 100%
D0A7X8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
E9AZP9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 99%
Q4Q8I4 Leishmania major 91% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS