Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IPX1_LEIDO

TriTrypDb:

LdBPK_271210.1 , LdCL_270018600 , LDHU3_27.1880

Length:

163

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IPX1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IPX1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	131	137	PF00089	0.581
CLV_NRD_NRD_1	24	26	PF00675	0.415
CLV_PCSK_KEX2_1	100	102	PF00082	0.542
CLV_PCSK_KEX2_1	24	26	PF00082	0.415
CLV_PCSK_PC1ET2_1	100	102	PF00082	0.542
DOC_MAPK_DCC_7	28	36	PF00069	0.400
DOC_MAPK_gen_1	134	144	PF00069	0.539
DOC_MAPK_MEF2A_6	28	36	PF00069	0.453
DOC_MAPK_MEF2A_6	71	78	PF00069	0.477
DOC_WW_Pin1_4	153	158	PF00397	0.567
DOC_WW_Pin1_4	51	56	PF00397	0.442
LIG_14-3-3_CanoR_1	120	127	PF00244	0.592
LIG_14-3-3_CanoR_1	152	157	PF00244	0.568
LIG_14-3-3_CanoR_1	24	32	PF00244	0.442
LIG_BRCT_BRCA1_1	118	122	PF00533	0.626
LIG_deltaCOP1_diTrp_1	115	122	PF00928	0.592
LIG_FHA_1	37	43	PF00498	0.391
LIG_FHA_2	154	160	PF00498	0.573
LIG_FHA_2	57	63	PF00498	0.489
LIG_FHA_2	87	93	PF00498	0.567
LIG_SH2_PTP2	33	36	PF00017	0.399
LIG_SH2_STAP1	83	87	PF00017	0.478
LIG_SH2_STAT5	33	36	PF00017	0.447
LIG_SH3_3	26	32	PF00018	0.452
LIG_TYR_ITIM	31	36	PF00017	0.395
MOD_CK1_1	123	129	PF00069	0.624
MOD_CK1_1	14	20	PF00069	0.461
MOD_CK1_1	151	157	PF00069	0.568
MOD_CK1_1	23	29	PF00069	0.392
MOD_CK1_1	56	62	PF00069	0.476
MOD_CK2_1	86	92	PF00069	0.513
MOD_GlcNHglycan	102	105	PF01048	0.534
MOD_GlcNHglycan	122	125	PF01048	0.687
MOD_GlcNHglycan	128	131	PF01048	0.687
MOD_GlcNHglycan	19	22	PF01048	0.487
MOD_GlcNHglycan	55	58	PF01048	0.439
MOD_GlcNHglycan	9	12	PF01048	0.453
MOD_GSK3_1	116	123	PF00069	0.672
MOD_GSK3_1	126	133	PF00069	0.509
MOD_GSK3_1	148	155	PF00069	0.568
MOD_GSK3_1	7	14	PF00069	0.447
MOD_NEK2_1	12	17	PF00069	0.529
MOD_PKA_1	100	106	PF00069	0.544
MOD_PKA_2	100	106	PF00069	0.605
MOD_PKA_2	133	139	PF00069	0.581
MOD_PKA_2	151	157	PF00069	0.568
MOD_PKA_2	23	29	PF00069	0.409
MOD_PKA_2	70	76	PF00069	0.490
MOD_PKB_1	118	126	PF00069	0.592
MOD_PKB_1	150	158	PF00069	0.570
MOD_ProDKin_1	153	159	PF00069	0.572
MOD_ProDKin_1	51	57	PF00069	0.440
TRG_DiLeu_BaEn_2	62	68	PF01217	0.536
TRG_ENDOCYTIC_2	33	36	PF00928	0.519
TRG_ER_diArg_1	117	120	PF00400	0.595
TRG_ER_diArg_1	141	144	PF00400	0.547
TRG_ER_diArg_1	145	148	PF00400	0.548
TRG_ER_diArg_1	149	152	PF00400	0.528

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I2T2	Leishmania infantum	100%	100%
E9ADB0	Leishmania major	87%	100%