Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IPH3_LEIDO

TriTrypDb:

LdBPK_352160.1 , LdCL_350026500 , LDHU3_35.2760

Length:

269

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IPH3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IPH3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	60	64	PF00656	0.726
CLV_PCSK_KEX2_1	243	245	PF00082	0.679
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.679
CLV_PCSK_SKI1_1	243	247	PF00082	0.682
DOC_PP2B_LxvP_1	251	254	PF13499	0.723
DOC_USP7_MATH_1	100	104	PF00917	0.750
DOC_USP7_MATH_1	114	118	PF00917	0.538
DOC_USP7_MATH_1	141	145	PF00917	0.651
DOC_USP7_MATH_1	168	172	PF00917	0.665
DOC_USP7_MATH_1	193	197	PF00917	0.786
DOC_WW_Pin1_4	108	113	PF00397	0.712
DOC_WW_Pin1_4	134	139	PF00397	0.810
DOC_WW_Pin1_4	146	151	PF00397	0.580
DOC_WW_Pin1_4	163	168	PF00397	0.532
LIG_14-3-3_CanoR_1	179	185	PF00244	0.752
LIG_14-3-3_CanoR_1	50	56	PF00244	0.681
LIG_BIR_II_1	1	5	PF00653	0.833
LIG_BIR_III_2	20	24	PF00653	0.719
LIG_BRCT_BRCA1_1	103	107	PF00533	0.828
LIG_BRCT_BRCA1_1	52	56	PF00533	0.680
LIG_EVH1_2	157	161	PF00568	0.755
LIG_FHA_1	206	212	PF00498	0.779
LIG_FHA_2	130	136	PF00498	0.702
LIG_FHA_2	172	178	PF00498	0.714
LIG_FHA_2	3	9	PF00498	0.757
LIG_LIR_Nem_3	125	130	PF02991	0.746
LIG_SH2_CRK	249	253	PF00017	0.728
LIG_SH2_STAP1	249	253	PF00017	0.630
LIG_SH3_3	133	139	PF00018	0.799
LIG_SH3_3	154	160	PF00018	0.721
LIG_TRAF2_1	174	177	PF00917	0.827
LIG_TRAF2_1	25	28	PF00917	0.732
LIG_TRAF2_1	67	70	PF00917	0.783
MOD_CK1_1	103	109	PF00069	0.750
MOD_CK1_1	122	128	PF00069	0.664
MOD_CK1_1	171	177	PF00069	0.642
MOD_CK1_1	2	8	PF00069	0.755
MOD_CK1_1	52	58	PF00069	0.695
MOD_CK2_1	129	135	PF00069	0.701
MOD_CK2_1	171	177	PF00069	0.713
MOD_CK2_1	22	28	PF00069	0.706
MOD_CK2_1	222	228	PF00069	0.737
MOD_GlcNHglycan	103	106	PF01048	0.675
MOD_GlcNHglycan	112	115	PF01048	0.692
MOD_GlcNHglycan	121	124	PF01048	0.562
MOD_GlcNHglycan	161	164	PF01048	0.705
MOD_GlcNHglycan	24	27	PF01048	0.654
MOD_GlcNHglycan	83	86	PF01048	0.739
MOD_GSK3_1	103	110	PF00069	0.730
MOD_GSK3_1	130	137	PF00069	0.818
MOD_GSK3_1	159	166	PF00069	0.671
MOD_GSK3_1	180	187	PF00069	0.754
MOD_GSK3_1	189	196	PF00069	0.660
MOD_GSK3_1	22	29	PF00069	0.717
MOD_GSK3_1	45	52	PF00069	0.769
MOD_NEK2_1	1	6	PF00069	0.656
MOD_NEK2_1	107	112	PF00069	0.654
MOD_NEK2_1	204	209	PF00069	0.694
MOD_NEK2_1	216	221	PF00069	0.501
MOD_PIKK_1	197	203	PF00454	0.719
MOD_PKA_2	49	55	PF00069	0.832
MOD_Plk_1	216	222	PF00069	0.556
MOD_Plk_4	141	147	PF00069	0.732
MOD_ProDKin_1	108	114	PF00069	0.715
MOD_ProDKin_1	134	140	PF00069	0.804
MOD_ProDKin_1	146	152	PF00069	0.579
MOD_ProDKin_1	163	169	PF00069	0.536
MOD_SUMO_for_1	91	94	PF00179	0.767
MOD_SUMO_rev_2	237	245	PF00179	0.671
MOD_SUMO_rev_2	59	67	PF00179	0.621
MOD_SUMO_rev_2	84	93	PF00179	0.832
TRG_ENDOCYTIC_2	249	252	PF00928	0.736
TRG_Pf-PMV_PEXEL_1	218	222	PF00026	0.554

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HMN4	Leishmania braziliensis	58%	100%
E9AF36	Leishmania major	86%	100%
E9AHV3	Leishmania infantum	99%	100%
E9B691	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%