Arrestin (Or S-antigen), N-terminal domain family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IP18_LEIDO

TriTrypDb:

LdBPK_350440.1 , LdCL_350009500 , LDHU3_35.0600

Length:

603

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IP18

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IP18

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	96	98	PF00675	0.803
CLV_PCSK_KEX2_1	241	243	PF00082	0.815
CLV_PCSK_KEX2_1	285	287	PF00082	0.761
CLV_PCSK_KEX2_1	55	57	PF00082	0.792
CLV_PCSK_KEX2_1	96	98	PF00082	0.803
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.815
CLV_PCSK_PC1ET2_1	285	287	PF00082	0.761
CLV_PCSK_PC1ET2_1	55	57	PF00082	0.792
CLV_PCSK_SKI1_1	109	113	PF00082	0.637
CLV_PCSK_SKI1_1	255	259	PF00082	0.755
CLV_PCSK_SKI1_1	317	321	PF00082	0.744
CLV_PCSK_SKI1_1	353	357	PF00082	0.659
CLV_PCSK_SKI1_1	44	48	PF00082	0.757
DEG_APCC_DBOX_1	43	51	PF00400	0.762
DEG_APCC_DBOX_1	96	104	PF00400	0.810
DEG_SPOP_SBC_1	553	557	PF00917	0.704
DOC_CKS1_1	216	221	PF01111	0.782
DOC_CYCLIN_RxL_1	252	261	PF00134	0.699
DOC_CYCLIN_yCln2_LP_2	250	256	PF00134	0.763
DOC_MAPK_DCC_7	96	105	PF00069	0.634
DOC_MAPK_gen_1	205	215	PF00069	0.732
DOC_MAPK_gen_1	321	330	PF00069	0.658
DOC_MAPK_gen_1	351	358	PF00069	0.651
DOC_MAPK_gen_1	470	478	PF00069	0.670
DOC_MAPK_gen_1	8	16	PF00069	0.576
DOC_MAPK_HePTP_8	320	332	PF00069	0.706
DOC_MAPK_MEF2A_6	255	262	PF00069	0.567
DOC_MAPK_MEF2A_6	323	332	PF00069	0.695
DOC_MAPK_MEF2A_6	351	358	PF00069	0.726
DOC_MAPK_MEF2A_6	96	105	PF00069	0.758
DOC_PP2B_LxvP_1	160	163	PF13499	0.702
DOC_PP2B_LxvP_1	358	361	PF13499	0.793
DOC_PP2B_LxvP_1	526	529	PF13499	0.691
DOC_PP4_FxxP_1	256	259	PF00568	0.748
DOC_PP4_MxPP_1	409	412	PF00568	0.653
DOC_USP7_MATH_1	176	180	PF00917	0.778
DOC_USP7_MATH_1	372	376	PF00917	0.841
DOC_USP7_MATH_1	38	42	PF00917	0.758
DOC_USP7_MATH_1	429	433	PF00917	0.734
DOC_USP7_MATH_1	516	520	PF00917	0.656
DOC_USP7_MATH_1	69	73	PF00917	0.783
DOC_USP7_UBL2_3	237	241	PF12436	0.650
DOC_USP7_UBL2_3	480	484	PF12436	0.658
DOC_WW_Pin1_4	140	145	PF00397	0.846
DOC_WW_Pin1_4	215	220	PF00397	0.773
DOC_WW_Pin1_4	249	254	PF00397	0.771
DOC_WW_Pin1_4	295	300	PF00397	0.764
DOC_WW_Pin1_4	420	425	PF00397	0.784
LIG_14-3-3_CanoR_1	184	188	PF00244	0.762
LIG_14-3-3_CanoR_1	208	213	PF00244	0.648
LIG_14-3-3_CanoR_1	331	335	PF00244	0.568
LIG_14-3-3_CanoR_1	345	350	PF00244	0.654
LIG_14-3-3_CanoR_1	4	8	PF00244	0.727
LIG_14-3-3_CanoR_1	490	495	PF00244	0.735
LIG_BRCT_BRCA1_1	297	301	PF00533	0.752
LIG_BRCT_BRCA1_1	518	522	PF00533	0.661
LIG_Clathr_ClatBox_1	257	261	PF01394	0.570
LIG_CSL_BTD_1	164	167	PF09270	0.722
LIG_CtBP_PxDLS_1	523	527	PF00389	0.672
LIG_FHA_1	108	114	PF00498	0.814
LIG_FHA_1	11	17	PF00498	0.765
LIG_FHA_1	209	215	PF00498	0.766
LIG_FHA_1	304	310	PF00498	0.615
LIG_FHA_1	386	392	PF00498	0.618
LIG_FHA_1	471	477	PF00498	0.671
LIG_FHA_1	548	554	PF00498	0.747
LIG_FHA_1	586	592	PF00498	0.778
LIG_FHA_2	29	35	PF00498	0.770
LIG_FHA_2	324	330	PF00498	0.690
LIG_FHA_2	507	513	PF00498	0.663
LIG_FHA_2	516	522	PF00498	0.524
LIG_FHA_2	533	539	PF00498	0.560
LIG_LIR_Apic_2	169	174	PF02991	0.774
LIG_LIR_Apic_2	540	545	PF02991	0.783
LIG_LIR_Gen_1	276	284	PF02991	0.621
LIG_LIR_Gen_1	395	404	PF02991	0.690
LIG_LIR_Gen_1	555	566	PF02991	0.675
LIG_LIR_Nem_3	276	280	PF02991	0.624
LIG_LIR_Nem_3	395	399	PF02991	0.683
LIG_LIR_Nem_3	555	561	PF02991	0.678
LIG_LIR_Nem_3	562	566	PF02991	0.558
LIG_MYND_1	164	168	PF01753	0.728
LIG_MYND_1	249	253	PF01753	0.775
LIG_NRBOX	315	321	PF00104	0.742
LIG_PTB_Apo_2	319	326	PF02174	0.724
LIG_PTB_Phospho_1	319	325	PF10480	0.731
LIG_SH2_CRK	396	400	PF00017	0.684
LIG_SH2_NCK_1	185	189	PF00017	0.787
LIG_SH2_NCK_1	325	329	PF00017	0.688
LIG_SH2_NCK_1	396	400	PF00017	0.808
LIG_SH2_NCK_1	503	507	PF00017	0.653
LIG_SH2_PTP2	154	157	PF00017	0.725
LIG_SH2_SRC	154	157	PF00017	0.725
LIG_SH2_STAP1	185	189	PF00017	0.780
LIG_SH2_STAP1	334	338	PF00017	0.595
LIG_SH2_STAT5	121	124	PF00017	0.810
LIG_SH2_STAT5	154	157	PF00017	0.725
LIG_SH2_STAT5	185	188	PF00017	0.780
LIG_SH2_STAT5	325	328	PF00017	0.687
LIG_SH2_STAT5	503	506	PF00017	0.706
LIG_SH2_STAT5	508	511	PF00017	0.568
LIG_SH3_3	161	167	PF00018	0.717
LIG_SH3_3	210	216	PF00018	0.769
LIG_SH3_3	257	263	PF00018	0.557
LIG_SH3_3	589	595	PF00018	0.786
LIG_SH3_3	65	71	PF00018	0.783
LIG_SH3_3	98	104	PF00018	0.638
LIG_SUMO_SIM_anti_2	199	204	PF11976	0.743
LIG_SUMO_SIM_anti_2	576	584	PF11976	0.794
LIG_SUMO_SIM_par_1	106	114	PF11976	0.639
LIG_SUMO_SIM_par_1	576	584	PF11976	0.794
LIG_TRAF2_1	49	52	PF00917	0.731
LIG_TRAF2_1	74	77	PF00917	0.770
LIG_WW_1	167	170	PF00397	0.757
MOD_CDC14_SPxK_1	252	255	PF00782	0.706
MOD_CDK_SPxK_1	249	255	PF00069	0.719
MOD_CDK_SPxxK_3	140	147	PF00069	0.841
MOD_CDK_SPxxK_3	295	302	PF00069	0.757
MOD_CK1_1	179	185	PF00069	0.699
MOD_CK1_1	375	381	PF00069	0.826
MOD_CK1_1	431	437	PF00069	0.826
MOD_CK1_1	448	454	PF00069	0.574
MOD_CK1_1	88	94	PF00069	0.629
MOD_CK2_1	439	445	PF00069	0.665
MOD_CK2_1	506	512	PF00069	0.663
MOD_CK2_1	515	521	PF00069	0.533
MOD_Cter_Amidation	53	56	PF01082	0.789
MOD_GlcNHglycan	174	177	PF01048	0.730
MOD_GlcNHglycan	246	249	PF01048	0.700
MOD_GlcNHglycan	280	283	PF01048	0.768
MOD_GlcNHglycan	335	339	PF01048	0.741
MOD_GlcNHglycan	365	368	PF01048	0.830
MOD_GlcNHglycan	374	377	PF01048	0.686
MOD_GlcNHglycan	40	43	PF01048	0.704
MOD_GlcNHglycan	433	436	PF01048	0.849
MOD_GlcNHglycan	445	448	PF01048	0.629
MOD_GlcNHglycan	450	453	PF01048	0.558
MOD_GlcNHglycan	492	495	PF01048	0.745
MOD_GSK3_1	10	17	PF00069	0.758
MOD_GSK3_1	103	110	PF00069	0.644
MOD_GSK3_1	115	122	PF00069	0.639
MOD_GSK3_1	172	179	PF00069	0.764
MOD_GSK3_1	225	232	PF00069	0.689
MOD_GSK3_1	330	337	PF00069	0.525
MOD_GSK3_1	439	446	PF00069	0.691
MOD_GSK3_1	472	479	PF00069	0.671
MOD_GSK3_1	504	511	PF00069	0.537
MOD_GSK3_1	85	92	PF00069	0.625
MOD_N-GLC_1	363	368	PF02516	0.822
MOD_N-GLC_1	516	521	PF02516	0.680
MOD_NEK2_1	183	188	PF00069	0.782
MOD_NEK2_1	3	8	PF00069	0.727
MOD_NEK2_1	385	390	PF00069	0.620
MOD_NEK2_1	532	537	PF00069	0.665
MOD_NEK2_1	559	564	PF00069	0.663
MOD_NEK2_1	587	592	PF00069	0.778
MOD_NEK2_1	64	69	PF00069	0.786
MOD_PIKK_1	206	212	PF00454	0.666
MOD_PK_1	345	351	PF00069	0.761
MOD_PK_1	472	478	PF00069	0.669
MOD_PKA_1	241	247	PF00069	0.808
MOD_PKA_2	10	16	PF00069	0.642
MOD_PKA_2	183	189	PF00069	0.781
MOD_PKA_2	225	231	PF00069	0.678
MOD_PKA_2	241	247	PF00069	0.617
MOD_PKA_2	293	299	PF00069	0.769
MOD_PKA_2	3	9	PF00069	0.727
MOD_PKA_2	330	336	PF00069	0.515
MOD_PKA_2	439	445	PF00069	0.692
MOD_PKA_2	489	495	PF00069	0.728
MOD_PKA_2	532	538	PF00069	0.663
MOD_PKA_2	85	91	PF00069	0.767
MOD_PKB_1	468	476	PF00069	0.663
MOD_PKB_1	488	496	PF00069	0.419
MOD_Plk_1	107	113	PF00069	0.812
MOD_Plk_1	275	281	PF00069	0.769
MOD_Plk_1	394	400	PF00069	0.631
MOD_Plk_1	516	522	PF00069	0.545
MOD_Plk_4	166	172	PF00069	0.756
MOD_Plk_4	208	214	PF00069	0.688
MOD_Plk_4	310	316	PF00069	0.680
MOD_Plk_4	345	351	PF00069	0.761
MOD_Plk_4	434	440	PF00069	0.798
MOD_Plk_4	554	560	PF00069	0.689
MOD_ProDKin_1	140	146	PF00069	0.842
MOD_ProDKin_1	215	221	PF00069	0.777
MOD_ProDKin_1	249	255	PF00069	0.769
MOD_ProDKin_1	295	301	PF00069	0.758
MOD_ProDKin_1	420	426	PF00069	0.784
MOD_SUMO_for_1	284	287	PF00179	0.758
TRG_DiLeu_BaEn_1	261	266	PF01217	0.724
TRG_DiLeu_BaEn_1	576	581	PF01217	0.792
TRG_DiLeu_BaEn_1	60	65	PF01217	0.794
TRG_DiLeu_BaLyEn_6	246	251	PF01217	0.789
TRG_ENDOCYTIC_2	325	328	PF00928	0.606
TRG_ENDOCYTIC_2	396	399	PF00928	0.682
TRG_ER_diArg_1	350	353	PF00400	0.625
TRG_ER_diArg_1	465	468	PF00400	0.651
TRG_ER_diArg_1	469	472	PF00400	0.636
TRG_Pf-PMV_PEXEL_1	286	290	PF00026	0.750

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4IAU4	Leishmania infantum	100%	100%
E9AEM2	Leishmania major	90%	100%
E9B5T1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%