Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8INN7_LEIDO

TriTrypDb:

LdBPK_252250.1 , LdCL_250028300 , LDHU3_25.2720

Length:

251

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8INN7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8INN7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	199	201	PF00675	0.466
CLV_PCSK_KEX2_1	213	215	PF00082	0.655
CLV_PCSK_PC1ET2_1	213	215	PF00082	0.655
CLV_PCSK_SKI1_1	135	139	PF00082	0.373
CLV_PCSK_SKI1_1	145	149	PF00082	0.376
CLV_PCSK_SKI1_1	170	174	PF00082	0.537
DEG_Nend_UBRbox_2	1	3	PF02207	0.577
DEG_SCF_FBW7_1	227	234	PF00400	0.586
DOC_CKS1_1	228	233	PF01111	0.497
DOC_MAPK_gen_1	151	161	PF00069	0.409
DOC_USP7_MATH_1	121	125	PF00917	0.368
DOC_USP7_MATH_1	146	150	PF00917	0.417
DOC_USP7_MATH_1	231	235	PF00917	0.653
DOC_USP7_MATH_1	72	76	PF00917	0.546
DOC_USP7_MATH_1	86	90	PF00917	0.592
DOC_WW_Pin1_4	227	232	PF00397	0.619
DOC_WW_Pin1_4	36	41	PF00397	0.606
DOC_WW_Pin1_4	67	72	PF00397	0.625
DOC_WW_Pin1_4	78	83	PF00397	0.571
LIG_14-3-3_CanoR_1	145	151	PF00244	0.510
LIG_Actin_RPEL_3	174	193	PF02755	0.385
LIG_Actin_WH2_2	4	21	PF00022	0.482
LIG_CaM_IQ_9	156	172	PF13499	0.356
LIG_FHA_1	103	109	PF00498	0.496
LIG_FHA_1	216	222	PF00498	0.672
LIG_FHA_1	237	243	PF00498	0.461
LIG_FHA_1	43	49	PF00498	0.592
LIG_FHA_2	8	14	PF00498	0.509
LIG_LIR_Gen_1	130	139	PF02991	0.468
LIG_LIR_Gen_1	182	192	PF02991	0.392
LIG_LIR_Gen_1	25	31	PF02991	0.649
LIG_LIR_Gen_1	99	109	PF02991	0.567
LIG_LIR_Nem_3	130	136	PF02991	0.469
LIG_LIR_Nem_3	149	153	PF02991	0.410
LIG_LIR_Nem_3	182	187	PF02991	0.452
LIG_LIR_Nem_3	243	249	PF02991	0.448
LIG_LIR_Nem_3	25	30	PF02991	0.663
LIG_LIR_Nem_3	99	104	PF02991	0.579
LIG_NRBOX	237	243	PF00104	0.461
LIG_Rb_LxCxE_1	182	202	PF01857	0.428
LIG_SH2_CRK	27	31	PF00017	0.518
LIG_SH2_NCK_1	27	31	PF00017	0.501
LIG_SH2_STAP1	176	180	PF00017	0.398
LIG_SH2_STAP1	27	31	PF00017	0.574
LIG_SH3_3	225	231	PF00018	0.508
LIG_SUMO_SIM_anti_2	191	197	PF11976	0.384
LIG_UBA3_1	132	138	PF00899	0.444
MOD_CDK_SPxxK_3	78	85	PF00069	0.648
MOD_CK1_1	168	174	PF00069	0.469
MOD_CK1_1	179	185	PF00069	0.363
MOD_CK1_1	206	212	PF00069	0.613
MOD_CK1_1	29	35	PF00069	0.613
MOD_CK1_1	58	64	PF00069	0.581
MOD_CK1_1	70	76	PF00069	0.652
MOD_CK1_1	88	94	PF00069	0.566
MOD_CK2_1	7	13	PF00069	0.518
MOD_CK2_1	86	92	PF00069	0.683
MOD_GlcNHglycan	165	170	PF01048	0.421
MOD_GlcNHglycan	177	181	PF01048	0.338
MOD_GSK3_1	175	182	PF00069	0.436
MOD_GSK3_1	203	210	PF00069	0.529
MOD_GSK3_1	227	234	PF00069	0.600
MOD_GSK3_1	32	39	PF00069	0.733
MOD_GSK3_1	54	61	PF00069	0.576
MOD_GSK3_1	84	91	PF00069	0.644
MOD_NEK2_1	31	36	PF00069	0.536
MOD_NEK2_2	146	151	PF00069	0.417
MOD_PIKK_1	29	35	PF00454	0.636
MOD_PIKK_1	72	78	PF00454	0.614
MOD_PIKK_1	86	92	PF00454	0.580
MOD_PKA_2	58	64	PF00069	0.644
MOD_PKA_2	84	90	PF00069	0.647
MOD_Plk_1	14	20	PF00069	0.460
MOD_Plk_4	104	110	PF00069	0.447
MOD_Plk_4	26	32	PF00069	0.585
MOD_ProDKin_1	227	233	PF00069	0.615
MOD_ProDKin_1	36	42	PF00069	0.607
MOD_ProDKin_1	67	73	PF00069	0.625
MOD_ProDKin_1	78	84	PF00069	0.573
MOD_SUMO_for_1	137	140	PF00179	0.367
MOD_SUMO_rev_2	206	215	PF00179	0.547
TRG_DiLeu_BaEn_1	191	196	PF01217	0.436
TRG_DiLeu_BaLyEn_6	148	153	PF01217	0.419
TRG_DiLeu_BaLyEn_6	39	44	PF01217	0.550
TRG_ENDOCYTIC_2	27	30	PF00928	0.514
TRG_Pf-PMV_PEXEL_1	247	251	PF00026	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYI0	Leptomonas seymouri	33%	100%
A4HEB9	Leishmania braziliensis	65%	100%
A4I1R4	Leishmania infantum	98%	100%
E9AXU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q9M2	Leishmania major	86%	100%