LeishMANIAdb
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40S ribosomal protein S19 protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
40S ribosomal protein S19 protein, putative
Gene product:
40S ribosomal protein S19 protein, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8INI0_LEIDO
TriTrypDb:
LdBPK_342620.1 , LdCL_340033800 , LDHU3_34.4270
Length:
179

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 35
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 7
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 21
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 17
NetGPI no yes: 0, no: 17
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 16
GO:0032991 protein-containing complex 1 18
GO:0043226 organelle 2 16
GO:0043228 non-membrane-bounded organelle 3 16
GO:0043229 intracellular organelle 3 16
GO:0043232 intracellular non-membrane-bounded organelle 4 16
GO:0110165 cellular anatomical entity 1 16
GO:1990904 ribonucleoprotein complex 2 18
GO:0015935 small ribosomal subunit 4 2
GO:0022627 cytosolic small ribosomal subunit 5 2
GO:0044391 ribosomal subunit 3 2

Expansion

Sequence features

A0A3Q8INI0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8INI0

Function

Biological processes
Term Name Level Count
GO:0006412 translation 4 18
GO:0006518 peptide metabolic process 4 18
GO:0006807 nitrogen compound metabolic process 2 18
GO:0008152 metabolic process 1 18
GO:0009058 biosynthetic process 2 18
GO:0009059 macromolecule biosynthetic process 4 18
GO:0009987 cellular process 1 18
GO:0019538 protein metabolic process 3 18
GO:0034641 cellular nitrogen compound metabolic process 3 18
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 18
GO:0043043 peptide biosynthetic process 5 18
GO:0043170 macromolecule metabolic process 3 18
GO:0043603 amide metabolic process 3 18
GO:0043604 amide biosynthetic process 4 18
GO:0044237 cellular metabolic process 2 18
GO:0044238 primary metabolic process 2 18
GO:0044249 cellular biosynthetic process 3 18
GO:0044260 obsolete cellular macromolecule metabolic process 3 18
GO:0044271 cellular nitrogen compound biosynthetic process 4 18
GO:0071704 organic substance metabolic process 2 18
GO:1901564 organonitrogen compound metabolic process 3 18
GO:1901566 organonitrogen compound biosynthetic process 4 18
GO:1901576 organic substance biosynthetic process 3 18
GO:0000028 ribosomal small subunit assembly 7 2
GO:0016043 cellular component organization 3 2
GO:0022607 cellular component assembly 4 2
GO:0022618 ribonucleoprotein complex assembly 6 2
GO:0043933 protein-containing complex organization 4 2
GO:0065003 protein-containing complex assembly 5 2
GO:0071826 ribonucleoprotein complex subunit organization 5 2
GO:0071840 cellular component organization or biogenesis 2 2
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 18
GO:0005198 structural molecule activity 1 18
GO:0003676 nucleic acid binding 3 2
GO:0003723 RNA binding 4 2
GO:0005488 binding 1 2
GO:0097159 organic cyclic compound binding 2 2
GO:1901363 heterocyclic compound binding 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_MEL_PAP_1 107 113 PF00089 0.271
CLV_NRD_NRD_1 11 13 PF00675 0.660
CLV_NRD_NRD_1 156 158 PF00675 0.283
CLV_NRD_NRD_1 172 174 PF00675 0.474
CLV_NRD_NRD_1 32 34 PF00675 0.569
CLV_PCSK_KEX2_1 109 111 PF00082 0.271
CLV_PCSK_KEX2_1 11 13 PF00082 0.644
CLV_PCSK_KEX2_1 32 34 PF00082 0.572
CLV_PCSK_PC1ET2_1 109 111 PF00082 0.271
CLV_PCSK_PC1ET2_1 32 34 PF00082 0.674
CLV_PCSK_SKI1_1 11 15 PF00082 0.446
CLV_PCSK_SKI1_1 137 141 PF00082 0.343
CLV_PCSK_SKI1_1 45 49 PF00082 0.317
CLV_PCSK_SKI1_1 52 56 PF00082 0.279
DEG_Nend_Nbox_1 1 3 PF02207 0.425
DEG_SPOP_SBC_1 125 129 PF00917 0.364
DOC_MAPK_gen_1 157 168 PF00069 0.283
DOC_MAPK_gen_1 52 62 PF00069 0.348
DOC_USP7_MATH_1 135 139 PF00917 0.344
DOC_USP7_MATH_1 5 9 PF00917 0.408
DOC_USP7_UBL2_3 137 141 PF12436 0.275
DOC_USP7_UBL2_3 55 59 PF12436 0.307
LIG_14-3-3_CanoR_1 33 39 PF00244 0.641
LIG_14-3-3_CanoR_1 45 54 PF00244 0.281
LIG_14-3-3_CanoR_1 6 10 PF00244 0.417
LIG_Actin_WH2_2 23 41 PF00022 0.615
LIG_BRCT_BRCA1_1 107 111 PF00533 0.271
LIG_BRCT_BRCA1_1 164 168 PF00533 0.376
LIG_FHA_1 127 133 PF00498 0.364
LIG_LIR_Nem_3 42 47 PF02991 0.419
LIG_LIR_Nem_3 83 87 PF02991 0.288
LIG_SH2_CRK 104 108 PF00017 0.290
LIG_SH2_STAT5 86 89 PF00017 0.288
LIG_SH2_STAT5 97 100 PF00017 0.271
LIG_SH3_3 10 16 PF00018 0.445
LIG_SH3_3 76 82 PF00018 0.284
LIG_TYR_ITIM 102 107 PF00017 0.300
LIG_UBA3_1 19 26 PF00899 0.474
MOD_CDC14_SPxK_1 3 6 PF00782 0.397
MOD_CK2_1 116 122 PF00069 0.271
MOD_Cter_Amidation 30 33 PF01082 0.551
MOD_GlcNHglycan 150 153 PF01048 0.309
MOD_GlcNHglycan 40 44 PF01048 0.419
MOD_GSK3_1 121 128 PF00069 0.410
MOD_N-GLC_1 63 68 PF02516 0.344
MOD_NEK2_1 162 167 PF00069 0.364
MOD_NEK2_1 69 74 PF00069 0.372
MOD_PKA_1 11 17 PF00069 0.447
MOD_PKA_2 153 159 PF00069 0.284
MOD_PKA_2 5 11 PF00069 0.417
MOD_Plk_1 121 127 PF00069 0.419
MOD_Plk_1 39 45 PF00069 0.431
MOD_Plk_4 5 11 PF00069 0.424
MOD_SUMO_for_1 54 57 PF00179 0.284
TRG_DiLeu_BaEn_2 56 62 PF01217 0.376
TRG_ENDOCYTIC_2 104 107 PF00928 0.271
TRG_ER_diArg_1 10 12 PF00400 0.652
TRG_NLS_MonoExtN_4 29 36 PF00514 0.550

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4IY51 Bodo saltans 66% 100%
A0A1D8PK61 Candida albicans (strain SC5314 / ATCC MYA-2876) 36% 100%
A0A1X0P9W6 Trypanosomatidae 69% 100%
A0A1X0P9X9 Trypanosomatidae 70% 100%
A0A3Q8IFE1 Leishmania donovani 96% 100%
A0A3R7KIF6 Trypanosoma rangeli 70% 100%
A0A422NEU2 Trypanosoma rangeli 71% 100%
A4H3R3 Leishmania braziliensis 95% 100%
A4HAZ5 Leishmania braziliensis 96% 100%
A4I4Y2 Leishmania infantum 96% 100%
A4IA55 Leishmania infantum 99% 100%
C9ZM47 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 68% 100%
E9AEE8 Leishmania major 96% 100%
E9ALD8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
E9B569 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
O15631 Entamoeba histolytica 37% 100%
O18650 Caenorhabditis elegans 35% 100%
O27653 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 34% 100%
O28210 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) 29% 100%
O59041 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 29% 100%
P07280 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 36% 100%
P07281 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 36% 100%
P17074 Rattus norvegicus 32% 100%
P19952 Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) 28% 100%
P24494 Ascaris suum 32% 100%
P27073 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) 40% 100%
P39018 Drosophila melanogaster 33% 100%
P39019 Homo sapiens 32% 100%
P39698 Ascaris suum 33% 100%
P40978 Oryza sativa subsp. japonica 35% 100%
P54057 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 39% 100%
P58234 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 38% 100%
P61155 Pagrus major 32% 100%
P79016 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 38% 100%
Q29308 Sus scrofa 31% 100%
Q32PD5 Bos taurus 32% 100%
Q4Q2R6 Leishmania major 98% 100%
Q54X51 Dictyostelium discoideum 34% 100%
Q5R8M9 Pongo abelii 32% 100%
Q7KS38 Drosophila melanogaster 34% 100%
Q8ITC3 Argopecten irradians 36% 100%
Q8T5Z4 Branchiostoma belcheri 35% 100%
Q90YQ4 Ictalurus punctatus 35% 100%
Q94613 Mya arenaria 34% 100%
Q9CZX8 Mus musculus 32% 100%
Q9DFR5 Gillichthys mirabilis 32% 100%
Q9FNP8 Arabidopsis thaliana 38% 100%
Q9HM21 Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) 30% 100%
Q9LF30 Arabidopsis thaliana 40% 100%
Q9SGA6 Arabidopsis thaliana 38% 100%
Q9V0G8 Pyrococcus abyssi (strain GE5 / Orsay) 30% 100%
Q9Y0H3 Myxine glutinosa 37% 100%
Q9YD22 Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) 27% 100%
V5DM12 Trypanosoma cruzi 70% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS