LeishMANIAdb
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Phospholipid-transporting ATPase-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phospholipid-transporting ATPase-like protein
Gene product:
phospholipid-transporting ATPase-like protein
Species:
Leishmania donovani
UniProt:
A0A3Q8ING5_LEIDO
TriTrypDb:
LdBPK_342460.1 * , LdCL_340032200 , LDHU3_34.4040
Length:
1491

Annotations

LeishMANIAdb annotations

Eukaryotic P-ATPase protein, its closest animal relatives (ATP11A) are involved in phospholipid transport.. Localization: Endosomal (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
TermNameLevelCount
GO:0005886 plasma membrane 3 1
GO:0016020 membrane 2 8
GO:0110165 cellular anatomical entity 1 8
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Expansion

Sequence features

A0A3Q8ING5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 2
GO:0006869 lipid transport 5 2
GO:0009987 cellular process 1 1
GO:0015748 organophosphate ester transport 5 2
GO:0015914 phospholipid transport 6 2
GO:0016043 cellular component organization 3 1
GO:0034204 lipid translocation 4 1
GO:0045332 phospholipid translocation 5 1
GO:0051179 localization 1 2
GO:0051234 establishment of localization 2 2
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 8
GO:0000287 magnesium ion binding 5 1
GO:0003824 catalytic activity 1 8
GO:0005215 transporter activity 1 8
GO:0005319 lipid transporter activity 2 8
GO:0005488 binding 1 8
GO:0005524 ATP binding 5 8
GO:0016462 pyrophosphatase activity 5 8
GO:0016787 hydrolase activity 2 8
GO:0016817 hydrolase activity, acting on acid anhydrides 3 8
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 161 165 PF00656 0.578
CLV_C14_Caspase3-7 173 177 PF00656 0.608
CLV_C14_Caspase3-7 217 221 PF00656 0.573
CLV_C14_Caspase3-7 785 789 PF00656 0.473
CLV_NRD_NRD_1 1061 1063 PF00675 0.340
CLV_NRD_NRD_1 107 109 PF00675 0.393
CLV_NRD_NRD_1 1144 1146 PF00675 0.346
CLV_NRD_NRD_1 246 248 PF00675 0.367
CLV_NRD_NRD_1 705 707 PF00675 0.226
CLV_NRD_NRD_1 730 732 PF00675 0.273
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IKQ9 Leptomonas seymouri 68% 99%
A0A0S4J0T6 Bodo saltans 26% 100%
A4HAY0 Leishmania braziliensis 78% 100%
A4IA39 Leishmania infantum 100% 100%
E9B554 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 99%
Q4Q2T2 Leishmania major 95% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS