Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IN96_LEIDO

TriTrypDb:

LdBPK_250810.1 , LdCL_250013400 , LDHU3_25.1020

Length:

306

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A0A3Q8IN96

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IN96

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	213	215	PF00675	0.529
CLV_NRD_NRD_1	57	59	PF00675	0.630
CLV_PCSK_FUR_1	211	215	PF00082	0.494
CLV_PCSK_KEX2_1	210	212	PF00082	0.528
CLV_PCSK_KEX2_1	213	215	PF00082	0.512
CLV_PCSK_PC1ET2_1	210	212	PF00082	0.499
CLV_PCSK_SKI1_1	141	145	PF00082	0.584
CLV_PCSK_SKI1_1	77	81	PF00082	0.598
DOC_CKS1_1	69	74	PF01111	0.365
DOC_CYCLIN_yCln2_LP_2	116	119	PF00134	0.397
DOC_MAPK_gen_1	58	65	PF00069	0.391
DOC_MAPK_MEF2A_6	58	67	PF00069	0.386
DOC_PP2B_LxvP_1	116	119	PF13499	0.428
DOC_USP7_MATH_1	119	123	PF00917	0.570
DOC_USP7_MATH_1	19	23	PF00917	0.462
DOC_USP7_MATH_1	203	207	PF00917	0.572
DOC_USP7_MATH_1	47	51	PF00917	0.434
DOC_USP7_MATH_1	87	91	PF00917	0.467
DOC_WW_Pin1_4	278	283	PF00397	0.688
DOC_WW_Pin1_4	292	297	PF00397	0.743
DOC_WW_Pin1_4	65	70	PF00397	0.398
LIG_Actin_WH2_2	125	143	PF00022	0.414
LIG_BIR_II_1	1	5	PF00653	0.479
LIG_FHA_1	102	108	PF00498	0.419
LIG_FHA_1	135	141	PF00498	0.409
LIG_FHA_1	33	39	PF00498	0.387
LIG_FHA_1	52	58	PF00498	0.430
LIG_FHA_2	137	143	PF00498	0.433
LIG_LIR_Apic_2	255	259	PF02991	0.739
LIG_LIR_Nem_3	129	134	PF02991	0.425
LIG_PTB_Apo_2	106	113	PF02174	0.384
LIG_SH2_CRK	256	260	PF00017	0.732
LIG_SH2_GRB2like	269	272	PF00017	0.747
LIG_SH2_STAT3	225	228	PF00017	0.731
LIG_SH2_STAT3	272	275	PF00017	0.714
LIG_SH2_STAT3	33	36	PF00017	0.426
LIG_SH3_3	220	226	PF00018	0.723
LIG_SH3_3	232	238	PF00018	0.700
LIG_SH3_3	257	263	PF00018	0.696
LIG_SH3_3	66	72	PF00018	0.365
LIG_SUMO_SIM_anti_2	21	28	PF11976	0.385
LIG_TRAF2_1	53	56	PF00917	0.408
LIG_WW_1	259	262	PF00397	0.694
MOD_CK1_1	22	28	PF00069	0.381
MOD_CK1_1	68	74	PF00069	0.395
MOD_CK2_1	203	209	PF00069	0.577
MOD_GlcNHglycan	12	15	PF01048	0.681
MOD_GlcNHglycan	145	148	PF01048	0.646
MOD_GlcNHglycan	154	159	PF01048	0.627
MOD_GlcNHglycan	200	203	PF01048	0.385
MOD_GlcNHglycan	205	208	PF01048	0.469
MOD_GlcNHglycan	272	275	PF01048	0.545
MOD_GlcNHglycan	49	52	PF01048	0.626
MOD_GlcNHglycan	89	92	PF01048	0.681
MOD_GSK3_1	290	297	PF00069	0.677
MOD_GSK3_1	47	54	PF00069	0.385
MOD_GSK3_1	6	13	PF00069	0.443
MOD_N-GLC_1	270	275	PF02516	0.545
MOD_NEK2_1	134	139	PF00069	0.466
MOD_NEK2_1	198	203	PF00069	0.385
MOD_PIKK_1	32	38	PF00454	0.386
MOD_PK_1	6	12	PF00069	0.392
MOD_PKA_1	213	219	PF00069	0.665
MOD_PKA_2	170	176	PF00069	0.356
MOD_PKA_2	213	219	PF00069	0.686
MOD_PKB_1	211	219	PF00069	0.665
MOD_Plk_1	29	35	PF00069	0.406
MOD_Plk_4	19	25	PF00069	0.421
MOD_ProDKin_1	278	284	PF00069	0.690
MOD_ProDKin_1	292	298	PF00069	0.742
MOD_ProDKin_1	65	71	PF00069	0.396
MOD_SUMO_rev_2	281	290	PF00179	0.684
TRG_DiLeu_BaEn_1	162	167	PF01217	0.375
TRG_DiLeu_BaEn_4	55	61	PF01217	0.414
TRG_ER_diArg_1	211	214	PF00400	0.695

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HE13	Leishmania braziliensis	53%	99%
A4I1C0	Leishmania infantum	100%	100%
E9AXF6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4QA16	Leishmania major	91%	100%