Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IN13_LEIDO

TriTrypDb:

LdBPK_242420.1 , LdCL_240029800 , LDHU3_24.2980

Length:

257

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IN13

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IN13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	112	114	PF00675	0.566
CLV_NRD_NRD_1	234	236	PF00675	0.577
CLV_NRD_NRD_1	237	239	PF00675	0.570
CLV_NRD_NRD_1	242	244	PF00675	0.586
CLV_NRD_NRD_1	43	45	PF00675	0.573
CLV_NRD_NRD_1	66	68	PF00675	0.533
CLV_NRD_NRD_1	93	95	PF00675	0.528
CLV_NRD_NRD_1	97	99	PF00675	0.502
CLV_PCSK_FUR_1	235	239	PF00082	0.576
CLV_PCSK_KEX2_1	231	233	PF00082	0.577
CLV_PCSK_KEX2_1	236	238	PF00082	0.577
CLV_PCSK_KEX2_1	242	244	PF00082	0.587
CLV_PCSK_KEX2_1	66	68	PF00082	0.507
CLV_PCSK_KEX2_1	93	95	PF00082	0.528
CLV_PCSK_PC1ET2_1	231	233	PF00082	0.577
CLV_PCSK_PC1ET2_1	236	238	PF00082	0.577
CLV_PCSK_PC1ET2_1	66	68	PF00082	0.480
CLV_PCSK_PC7_1	232	238	PF00082	0.577
CLV_PCSK_SKI1_1	121	125	PF00082	0.632
CLV_PCSK_SKI1_1	242	246	PF00082	0.590
CLV_PCSK_SKI1_1	31	35	PF00082	0.582
CLV_PCSK_SKI1_1	55	59	PF00082	0.530
DEG_Nend_UBRbox_2	1	3	PF02207	0.813
DOC_MAPK_gen_1	66	75	PF00069	0.592
DOC_USP7_UBL2_3	68	72	PF12436	0.626
LIG_14-3-3_CanoR_1	11	17	PF00244	0.608
LIG_14-3-3_CanoR_1	113	118	PF00244	0.520
LIG_14-3-3_CanoR_1	137	143	PF00244	0.615
LIG_14-3-3_CanoR_1	93	102	PF00244	0.493
LIG_CaM_IQ_9	193	208	PF13499	0.630
LIG_deltaCOP1_diTrp_1	59	64	PF00928	0.561
LIG_FHA_1	52	58	PF00498	0.639
LIG_FHA_2	15	21	PF00498	0.667
LIG_FHA_2	155	161	PF00498	0.517
LIG_FHA_2	186	192	PF00498	0.350
LIG_LIR_Gen_1	130	136	PF02991	0.451
LIG_LIR_Gen_1	58	69	PF02991	0.504
LIG_LIR_Nem_3	130	134	PF02991	0.469
LIG_LIR_Nem_3	36	41	PF02991	0.518
LIG_LIR_Nem_3	58	64	PF02991	0.522
LIG_NRBOX	160	166	PF00104	0.602
LIG_SH2_STAT3	129	132	PF00017	0.538
LIG_SH2_STAT5	74	77	PF00017	0.549
LIG_UBA3_1	106	114	PF00899	0.514
LIG_WRC_WIRS_1	13	18	PF05994	0.589
MOD_CK1_1	14	20	PF00069	0.486
MOD_CK2_1	138	144	PF00069	0.606
MOD_CK2_1	185	191	PF00069	0.352
MOD_CK2_1	45	51	PF00069	0.655
MOD_GlcNHglycan	99	102	PF01048	0.558
MOD_GSK3_1	51	58	PF00069	0.724
MOD_GSK3_1	93	100	PF00069	0.563
MOD_LATS_1	53	59	PF00433	0.585
MOD_NEK2_1	164	169	PF00069	0.508
MOD_PIKK_1	164	170	PF00454	0.541
MOD_PKA_1	113	119	PF00069	0.478
MOD_PKA_1	93	99	PF00069	0.535
MOD_PKA_2	93	99	PF00069	0.565
MOD_PKB_1	9	17	PF00069	0.594
MOD_Plk_4	113	119	PF00069	0.576
MOD_SUMO_rev_2	141	150	PF00179	0.518
MOD_SUMO_rev_2	79	87	PF00179	0.460
MOD_SUMO_rev_2	91	101	PF00179	0.515
TRG_DiLeu_BaEn_1	203	208	PF01217	0.523
TRG_DiLeu_BaEn_1	76	81	PF01217	0.420
TRG_DiLeu_BaEn_4	203	209	PF01217	0.525
TRG_DiLeu_LyEn_5	203	208	PF01217	0.523
TRG_ENDOCYTIC_2	131	134	PF00928	0.597
TRG_ER_diArg_1	235	238	PF00400	0.580
TRG_ER_diArg_1	93	95	PF00400	0.528
TRG_Pf-PMV_PEXEL_1	206	210	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	93	97	PF00026	0.519

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3B7	Leptomonas seymouri	40%	98%
A4HDU4	Leishmania braziliensis	71%	100%
A4I141	Leishmania infantum	98%	100%
E9AX79	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4QA97	Leishmania major	87%	100%