RNA-binding protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IMA7_LEIDO

TriTrypDb:

LdBPK_331560.1 , LdCL_330022200 , LDHU3_33.2380

Length:

128

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 18
NetGPI	no	yes: 0, no: 18

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8IMA7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IMA7

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	19
GO:0003723	RNA binding	4	19
GO:0005488	binding	1	19
GO:0097159	organic cyclic compound binding	2	19
GO:1901363	heterocyclic compound binding	2	19

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	96	98	PF00675	0.521
CLV_PCSK_KEX2_1	96	98	PF00082	0.532
CLV_PCSK_SKI1_1	35	39	PF00082	0.270
DOC_USP7_MATH_1	74	78	PF00917	0.504
DOC_USP7_UBL2_3	111	115	PF12436	0.574
DOC_WW_Pin1_4	99	104	PF00397	0.465
LIG_14-3-3_CanoR_1	35	41	PF00244	0.485
LIG_14-3-3_CanoR_1	66	73	PF00244	0.523
LIG_14-3-3_CanoR_1	96	104	PF00244	0.516
LIG_Actin_WH2_2	37	53	PF00022	0.523
LIG_BIR_III_4	52	56	PF00653	0.523
LIG_FHA_1	15	21	PF00498	0.476
LIG_FHA_1	45	51	PF00498	0.523
LIG_FHA_1	62	68	PF00498	0.476
LIG_FHA_2	28	34	PF00498	0.428
LIG_LIR_Gen_1	60	67	PF02991	0.475
LIG_LIR_Gen_1	70	78	PF02991	0.501
LIG_LIR_Nem_3	39	44	PF02991	0.421
LIG_LIR_Nem_3	60	65	PF02991	0.423
LIG_SH2_SRC	106	109	PF00017	0.484
LIG_SH2_STAP1	106	110	PF00017	0.499
LIG_SH2_STAT5	94	97	PF00017	0.386
LIG_SH3_3	117	123	PF00018	0.442
LIG_WRC_WIRS_1	37	42	PF05994	0.523
LIG_WRC_WIRS_1	62	67	PF05994	0.501
MOD_CK1_1	57	63	PF00069	0.431
MOD_GlcNHglycan	14	17	PF01048	0.522
MOD_GlcNHglycan	59	62	PF01048	0.228
MOD_GSK3_1	57	64	PF00069	0.466
MOD_GSK3_1	95	102	PF00069	0.368
MOD_N-GLC_1	115	120	PF02516	0.581
MOD_N-GLC_1	3	8	PF02516	0.619
MOD_NEK2_1	90	95	PF00069	0.347
MOD_NEK2_2	61	66	PF00069	0.523
MOD_NEK2_2	74	79	PF00069	0.469
MOD_PKA_2	65	71	PF00069	0.523
MOD_PKA_2	95	101	PF00069	0.528
MOD_ProDKin_1	99	105	PF00069	0.457
MOD_SUMO_rev_2	52	58	PF00179	0.523
TRG_ENDOCYTIC_2	41	44	PF00928	0.416

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5Z2	Leptomonas seymouri	29%	96%
A0A0N1I2T7	Leptomonas seymouri	89%	100%
A0A0S4J311	Bodo saltans	59%	100%
A0A0S4JKJ5	Bodo saltans	38%	69%
A0A1X0NTL2	Trypanosomatidae	45%	70%
A0A1X0P0Y7	Trypanosomatidae	59%	100%
A0A1X0P102	Trypanosomatidae	60%	100%
A0A1X0P2H6	Trypanosomatidae	32%	91%
A0A3R7KDP6	Trypanosoma rangeli	59%	100%
A0A422NG57	Trypanosoma rangeli	61%	100%
A4HIQ2	Leishmania braziliensis	30%	91%
A4HLK8	Leishmania braziliensis	94%	100%
A4I919	Leishmania infantum	99%	100%
C9ZRC4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	84%
C9ZRQ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	71%
D0A516	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	62%	100%
D0A517	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	100%
E9B3Y3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	74%
E9B3Y4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q4Q440	Leishmania major	96%	100%
Q9LIS2	Arabidopsis thaliana	34%	94%