PSP1 C-terminal conserved region containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PSP1 C-terminal conserved region, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IM55_LEIDO

TriTrypDb:

LdBPK_331070.1 , LdCL_330016800 , LDHU3_33.1660

Length:

908

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8IM55

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IM55

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	300	304	PF00656	0.672
CLV_C14_Caspase3-7	413	417	PF00656	0.622
CLV_C14_Caspase3-7	897	901	PF00656	0.648
CLV_NRD_NRD_1	11	13	PF00675	0.591
CLV_NRD_NRD_1	145	147	PF00675	0.730
CLV_NRD_NRD_1	289	291	PF00675	0.598
CLV_NRD_NRD_1	311	313	PF00675	0.674
CLV_NRD_NRD_1	57	59	PF00675	0.737
CLV_NRD_NRD_1	602	604	PF00675	0.532
CLV_NRD_NRD_1	799	801	PF00675	0.351
CLV_NRD_NRD_1	852	854	PF00675	0.405
CLV_NRD_NRD_1	99	101	PF00675	0.720
CLV_PCSK_FUR_1	97	101	PF00082	0.675
CLV_PCSK_KEX2_1	11	13	PF00082	0.591
CLV_PCSK_KEX2_1	145	147	PF00082	0.732
CLV_PCSK_KEX2_1	289	291	PF00082	0.598
CLV_PCSK_KEX2_1	311	313	PF00082	0.722
CLV_PCSK_KEX2_1	57	59	PF00082	0.737
CLV_PCSK_KEX2_1	602	604	PF00082	0.532
CLV_PCSK_KEX2_1	798	800	PF00082	0.368
CLV_PCSK_KEX2_1	97	99	PF00082	0.726
CLV_PCSK_PC1ET2_1	602	604	PF00082	0.507
CLV_PCSK_PC7_1	94	100	PF00082	0.674
CLV_PCSK_SKI1_1	265	269	PF00082	0.656
CLV_PCSK_SKI1_1	800	804	PF00082	0.501
CLV_PCSK_SKI1_1	817	821	PF00082	0.405
CLV_PCSK_SKI1_1	842	846	PF00082	0.405
CLV_PCSK_SKI1_1	853	857	PF00082	0.292
CLV_Separin_Metazoa	637	641	PF03568	0.388
DEG_COP1_1	879	887	PF00400	0.539
DEG_SPOP_SBC_1	25	29	PF00917	0.666
DEG_SPOP_SBC_1	41	45	PF00917	0.586
DOC_CKS1_1	319	324	PF01111	0.558
DOC_CKS1_1	887	892	PF01111	0.574
DOC_CYCLIN_RxL_1	849	858	PF00134	0.405
DOC_CYCLIN_yCln2_LP_2	711	717	PF00134	0.489
DOC_MAPK_DCC_7	798	807	PF00069	0.332
DOC_MAPK_gen_1	164	174	PF00069	0.613
DOC_MAPK_gen_1	798	807	PF00069	0.332
DOC_MAPK_gen_1	830	837	PF00069	0.405
DOC_MAPK_gen_1	839	848	PF00069	0.312
DOC_MAPK_gen_1	857	865	PF00069	0.220
DOC_MAPK_MEF2A_6	591	599	PF00069	0.470
DOC_MAPK_MEF2A_6	65	74	PF00069	0.660
DOC_MAPK_MEF2A_6	830	837	PF00069	0.405
DOC_MAPK_MEF2A_6	839	848	PF00069	0.312
DOC_MAPK_NFAT4_5	830	838	PF00069	0.405
DOC_PP2B_LxvP_1	453	456	PF13499	0.588
DOC_SPAK_OSR1_1	586	590	PF12202	0.566
DOC_USP7_MATH_1	214	218	PF00917	0.674
DOC_USP7_MATH_1	25	29	PF00917	0.681
DOC_USP7_MATH_1	32	36	PF00917	0.601
DOC_USP7_MATH_1	39	43	PF00917	0.594
DOC_USP7_MATH_1	404	408	PF00917	0.537
DOC_USP7_MATH_1	427	431	PF00917	0.682
DOC_USP7_MATH_1	465	469	PF00917	0.610
DOC_USP7_MATH_1	570	574	PF00917	0.715
DOC_USP7_MATH_1	620	624	PF00917	0.538
DOC_USP7_MATH_1	767	771	PF00917	0.363
DOC_USP7_MATH_1	780	784	PF00917	0.293
DOC_USP7_MATH_1	885	889	PF00917	0.673
DOC_USP7_UBL2_3	576	580	PF12436	0.697
DOC_WW_Pin1_4	124	129	PF00397	0.713
DOC_WW_Pin1_4	14	19	PF00397	0.630
DOC_WW_Pin1_4	229	234	PF00397	0.694
DOC_WW_Pin1_4	295	300	PF00397	0.653
DOC_WW_Pin1_4	315	320	PF00397	0.498
DOC_WW_Pin1_4	499	504	PF00397	0.678
DOC_WW_Pin1_4	612	617	PF00397	0.398
DOC_WW_Pin1_4	800	805	PF00397	0.417
DOC_WW_Pin1_4	883	888	PF00397	0.563
LIG_14-3-3_CanoR_1	12	18	PF00244	0.549
LIG_14-3-3_CanoR_1	171	181	PF00244	0.682
LIG_14-3-3_CanoR_1	311	315	PF00244	0.640
LIG_14-3-3_CanoR_1	40	46	PF00244	0.688
LIG_14-3-3_CanoR_1	563	570	PF00244	0.689
LIG_14-3-3_CanoR_1	572	579	PF00244	0.653
LIG_14-3-3_CanoR_1	640	645	PF00244	0.376
LIG_14-3-3_CanoR_1	65	73	PF00244	0.668
LIG_14-3-3_CanoR_1	97	105	PF00244	0.717
LIG_Actin_WH2_2	554	571	PF00022	0.581
LIG_BIR_II_1	1	5	PF00653	0.563
LIG_BRCT_BRCA1_1	161	165	PF00533	0.626
LIG_BRCT_BRCA1_1	419	423	PF00533	0.609
LIG_BRCT_BRCA1_1	879	883	PF00533	0.629
LIG_BRCT_BRCA1_1	887	891	PF00533	0.599
LIG_CtBP_PxDLS_1	254	258	PF00389	0.641
LIG_EVH1_1	453	457	PF00568	0.602
LIG_FHA_1	174	180	PF00498	0.595
LIG_FHA_1	222	228	PF00498	0.634
LIG_FHA_1	489	495	PF00498	0.611
LIG_FHA_1	553	559	PF00498	0.578
LIG_FHA_1	832	838	PF00498	0.405
LIG_FHA_1	902	908	PF00498	0.618
LIG_FHA_2	127	133	PF00498	0.720
LIG_FHA_2	189	195	PF00498	0.695
LIG_FHA_2	420	426	PF00498	0.644
LIG_FHA_2	613	619	PF00498	0.399
LIG_FHA_2	714	720	PF00498	0.460
LIG_FHA_2	818	824	PF00498	0.405
LIG_FHA_2	895	901	PF00498	0.697
LIG_HP1_1	70	74	PF01393	0.660
LIG_IBAR_NPY_1	69	71	PF08397	0.704
LIG_Integrin_RGD_1	898	900	PF01839	0.654
LIG_LIR_Apic_2	329	335	PF02991	0.803
LIG_LIR_Gen_1	420	431	PF02991	0.676
LIG_LIR_Gen_1	468	475	PF02991	0.646
LIG_LIR_Gen_1	879	887	PF02991	0.648
LIG_LIR_Nem_3	420	426	PF02991	0.680
LIG_LIR_Nem_3	468	472	PF02991	0.640
LIG_LIR_Nem_3	707	711	PF02991	0.490
LIG_LIR_Nem_3	879	884	PF02991	0.637
LIG_LYPXL_yS_3	375	378	PF13949	0.674
LIG_PCNA_yPIPBox_3	656	666	PF02747	0.503
LIG_PDZ_Class_3	903	908	PF00595	0.690
LIG_SH2_CRK	385	389	PF00017	0.689
LIG_SH2_CRK	399	403	PF00017	0.531
LIG_SH2_CRK	450	454	PF00017	0.660
LIG_SH2_CRK	461	465	PF00017	0.553
LIG_SH2_GRB2like	105	108	PF00017	0.702
LIG_SH2_NCK_1	385	389	PF00017	0.689
LIG_SH2_NCK_1	399	403	PF00017	0.531
LIG_SH2_PTP2	71	74	PF00017	0.714
LIG_SH2_SRC	332	335	PF00017	0.719
LIG_SH2_SRC	365	368	PF00017	0.687
LIG_SH2_SRC	399	402	PF00017	0.640
LIG_SH2_STAP1	610	614	PF00017	0.457
LIG_SH2_STAT3	355	358	PF00017	0.635
LIG_SH2_STAT3	384	387	PF00017	0.714
LIG_SH2_STAT5	365	368	PF00017	0.687
LIG_SH2_STAT5	452	455	PF00017	0.655
LIG_SH2_STAT5	701	704	PF00017	0.499
LIG_SH2_STAT5	71	74	PF00017	0.714
LIG_SH2_STAT5	749	752	PF00017	0.344
LIG_SH2_STAT5	836	839	PF00017	0.405
LIG_SH3_1	398	404	PF00018	0.635
LIG_SH3_3	155	161	PF00018	0.714
LIG_SH3_3	316	322	PF00018	0.653
LIG_SH3_3	373	379	PF00018	0.561
LIG_SH3_3	398	404	PF00018	0.684
LIG_SH3_3	451	457	PF00018	0.619
LIG_SH3_3	531	537	PF00018	0.788
LIG_SH3_3	76	82	PF00018	0.660
LIG_SH3_3	834	840	PF00018	0.405
LIG_SH3_3	879	885	PF00018	0.642
LIG_SH3_4	738	745	PF00018	0.405
LIG_SUMO_SIM_anti_2	818	823	PF11976	0.405
LIG_SUMO_SIM_par_1	803	809	PF11976	0.376
LIG_SUMO_SIM_par_1	811	816	PF11976	0.351
LIG_TRAF2_1	615	618	PF00917	0.545
LIG_TRAF2_1	806	809	PF00917	0.405
LIG_TRAF2_1	82	85	PF00917	0.695
LIG_WRC_WIRS_1	466	471	PF05994	0.637
LIG_WRC_WIRS_1	856	861	PF05994	0.405
MOD_CDK_SPxK_1	295	301	PF00069	0.572
MOD_CK1_1	101	107	PF00069	0.709
MOD_CK1_1	120	126	PF00069	0.526
MOD_CK1_1	210	216	PF00069	0.681
MOD_CK1_1	217	223	PF00069	0.660
MOD_CK1_1	261	267	PF00069	0.690
MOD_CK1_1	269	275	PF00069	0.655
MOD_CK1_1	27	33	PF00069	0.598
MOD_CK1_1	297	303	PF00069	0.666
MOD_CK1_1	318	324	PF00069	0.561
MOD_CK1_1	42	48	PF00069	0.629
MOD_CK1_1	53	59	PF00069	0.617
MOD_CK1_1	539	545	PF00069	0.763
MOD_CK1_1	557	563	PF00069	0.573
MOD_CK1_1	704	710	PF00069	0.553
MOD_CK1_1	838	844	PF00069	0.405
MOD_CK1_1	886	892	PF00069	0.572
MOD_CK2_1	190	196	PF00069	0.644
MOD_CK2_1	244	250	PF00069	0.634
MOD_CK2_1	269	275	PF00069	0.718
MOD_CK2_1	310	316	PF00069	0.694
MOD_CK2_1	419	425	PF00069	0.638
MOD_CK2_1	612	618	PF00069	0.467
MOD_CK2_1	803	809	PF00069	0.405
MOD_CK2_1	84	90	PF00069	0.718
MOD_GlcNHglycan	140	143	PF01048	0.718
MOD_GlcNHglycan	18	21	PF01048	0.671
MOD_GlcNHglycan	209	212	PF01048	0.692
MOD_GlcNHglycan	236	239	PF01048	0.706
MOD_GlcNHglycan	268	271	PF01048	0.693
MOD_GlcNHglycan	412	415	PF01048	0.628
MOD_GlcNHglycan	441	444	PF01048	0.603
MOD_GlcNHglycan	473	476	PF01048	0.684
MOD_GlcNHglycan	480	483	PF01048	0.681
MOD_GlcNHglycan	529	532	PF01048	0.744
MOD_GlcNHglycan	564	567	PF01048	0.677
MOD_GlcNHglycan	781	785	PF01048	0.383
MOD_GlcNHglycan	786	789	PF01048	0.375
MOD_GlcNHglycan	85	89	PF01048	0.667
MOD_GSK3_1	117	124	PF00069	0.543
MOD_GSK3_1	170	177	PF00069	0.652
MOD_GSK3_1	182	189	PF00069	0.616
MOD_GSK3_1	210	217	PF00069	0.697
MOD_GSK3_1	229	236	PF00069	0.585
MOD_GSK3_1	261	268	PF00069	0.606
MOD_GSK3_1	271	278	PF00069	0.600
MOD_GSK3_1	40	47	PF00069	0.671
MOD_GSK3_1	473	480	PF00069	0.663
MOD_GSK3_1	511	518	PF00069	0.737
MOD_GSK3_1	52	59	PF00069	0.636
MOD_GSK3_1	538	545	PF00069	0.694
MOD_GSK3_1	548	555	PF00069	0.594
MOD_GSK3_1	557	564	PF00069	0.561
MOD_GSK3_1	568	575	PF00069	0.550
MOD_GSK3_1	780	787	PF00069	0.280
MOD_GSK3_1	813	820	PF00069	0.405
MOD_GSK3_1	831	838	PF00069	0.405
MOD_GSK3_1	99	106	PF00069	0.649
MOD_N-GLC_1	106	111	PF02516	0.573
MOD_N-GLC_1	120	125	PF02516	0.575
MOD_N-GLC_1	218	223	PF02516	0.685
MOD_N-GLC_1	243	248	PF02516	0.615
MOD_N-GLC_1	261	266	PF02516	0.564
MOD_N-GLC_1	404	409	PF02516	0.561
MOD_N-GLC_1	63	68	PF02516	0.653
MOD_N-GLC_1	800	805	PF02516	0.405
MOD_NEK2_1	1	6	PF00069	0.539
MOD_NEK2_1	133	138	PF00069	0.657
MOD_NEK2_1	172	177	PF00069	0.689
MOD_NEK2_1	218	223	PF00069	0.702
MOD_NEK2_1	266	271	PF00069	0.656
MOD_NEK2_1	410	415	PF00069	0.571
MOD_NEK2_1	543	548	PF00069	0.567
MOD_NEK2_1	63	68	PF00069	0.690
MOD_NEK2_1	835	840	PF00069	0.405
MOD_NEK2_1	855	860	PF00069	0.199
MOD_NEK2_2	326	331	PF00069	0.580
MOD_NEK2_2	701	706	PF00069	0.506
MOD_PIKK_1	107	113	PF00454	0.688
MOD_PIKK_1	146	152	PF00454	0.722
MOD_PIKK_1	281	287	PF00454	0.705
MOD_PIKK_1	473	479	PF00454	0.705
MOD_PIKK_1	488	494	PF00454	0.556
MOD_PIKK_1	515	521	PF00454	0.802
MOD_PIKK_1	552	558	PF00454	0.657
MOD_PKA_1	98	104	PF00069	0.719
MOD_PKA_2	170	176	PF00069	0.620
MOD_PKA_2	207	213	PF00069	0.620
MOD_PKA_2	276	282	PF00069	0.592
MOD_PKA_2	310	316	PF00069	0.646
MOD_PKA_2	39	45	PF00069	0.689
MOD_PKA_2	477	483	PF00069	0.685
MOD_PKA_2	56	62	PF00069	0.586
MOD_PKA_2	562	568	PF00069	0.644
MOD_PKA_2	571	577	PF00069	0.610
MOD_PKA_2	64	70	PF00069	0.630
MOD_PKA_2	838	844	PF00069	0.405
MOD_PKA_2	98	104	PF00069	0.719
MOD_PKB_1	97	105	PF00069	0.719
MOD_Plk_1	218	224	PF00069	0.631
MOD_Plk_1	243	249	PF00069	0.609
MOD_Plk_1	261	267	PF00069	0.562
MOD_Plk_1	404	410	PF00069	0.566
MOD_Plk_1	817	823	PF00069	0.405
MOD_Plk_1	84	90	PF00069	0.690
MOD_Plk_4	326	332	PF00069	0.644
MOD_Plk_4	448	454	PF00069	0.664
MOD_Plk_4	817	823	PF00069	0.405
MOD_Plk_4	877	883	PF00069	0.621
MOD_ProDKin_1	124	130	PF00069	0.714
MOD_ProDKin_1	14	20	PF00069	0.632
MOD_ProDKin_1	229	235	PF00069	0.688
MOD_ProDKin_1	295	301	PF00069	0.657
MOD_ProDKin_1	315	321	PF00069	0.498
MOD_ProDKin_1	499	505	PF00069	0.681
MOD_ProDKin_1	612	618	PF00069	0.401
MOD_ProDKin_1	800	806	PF00069	0.417
MOD_ProDKin_1	883	889	PF00069	0.564
MOD_SUMO_rev_2	806	813	PF00179	0.356
MOD_SUMO_rev_2	900	907	PF00179	0.555
TRG_DiLeu_BaEn_2	878	884	PF01217	0.632
TRG_DiLeu_BaEn_4	808	814	PF01217	0.405
TRG_ENDOCYTIC_2	375	378	PF00928	0.674
TRG_ENDOCYTIC_2	385	388	PF00928	0.608
TRG_ENDOCYTIC_2	428	431	PF00928	0.661
TRG_ENDOCYTIC_2	450	453	PF00928	0.662
TRG_ENDOCYTIC_2	461	464	PF00928	0.553
TRG_ENDOCYTIC_2	71	74	PF00928	0.714
TRG_ER_diArg_1	144	146	PF00400	0.726
TRG_ER_diArg_1	206	209	PF00400	0.707
TRG_ER_diArg_1	57	60	PF00400	0.687
TRG_ER_diArg_1	657	660	PF00400	0.616
TRG_ER_diArg_1	798	800	PF00400	0.365
TRG_ER_diArg_1	859	862	PF00400	0.405
TRG_ER_diArg_1	96	99	PF00400	0.721
TRG_NES_CRM1_1	634	645	PF08389	0.504

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HLF5	Leishmania braziliensis	64%	100%
A4I8W6	Leishmania infantum	98%	100%
E9B3T5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4Q489	Leishmania major	88%	100%