BT1 family, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

BT1 family, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8ILR5_LEIDO

TriTrypDb:

LdBPK_323870.1 , LdCL_320044700 , LDHU3_32.5000

Length:

475

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	13
GO:0110165	cellular anatomical entity	1	13

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Expansion

Sequence features

A0A3Q8ILR5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ILR5

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0008643	carbohydrate transport	5	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0071702	organic substance transport	4	1

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	456	460	PF00656	0.646
CLV_NRD_NRD_1	191	193	PF00675	0.312
CLV_NRD_NRD_1	217	219	PF00675	0.388
CLV_NRD_NRD_1	290	292	PF00675	0.226
CLV_NRD_NRD_1	445	447	PF00675	0.415
CLV_NRD_NRD_1	66	68	PF00675	0.263
CLV_PCSK_KEX2_1	191	193	PF00082	0.351
CLV_PCSK_KEX2_1	217	219	PF00082	0.419
CLV_PCSK_KEX2_1	290	292	PF00082	0.226
CLV_PCSK_KEX2_1	445	447	PF00082	0.415

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYC7	Leptomonas seymouri	24%	86%
A0A0N1I3H1	Leptomonas seymouri	63%	69%
A0A3Q8IF44	Leishmania donovani	26%	100%
A4HIW8	Leishmania braziliensis	26%	100%
A4HL09	Leishmania braziliensis	78%	100%
A4I8J0	Leishmania infantum	100%	100%
E9AHK6	Leishmania infantum	26%	100%
E9B1F2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B3F0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q4Q0	Leishmania major	88%	100%

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