Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ILP8_LEIDO

TriTrypDb:

LdBPK_221240.1 , LdCL_220019500 , LDHU3_22.1790

Length:

411

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ILP8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ILP8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	9	13	PF00656	0.604
CLV_PCSK_KEX2_1	132	134	PF00082	0.504
CLV_PCSK_KEX2_1	222	224	PF00082	0.351
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.406
CLV_PCSK_PC1ET2_1	222	224	PF00082	0.365
CLV_PCSK_SKI1_1	311	315	PF00082	0.374
CLV_PCSK_SKI1_1	350	354	PF00082	0.312
CLV_PCSK_SKI1_1	365	369	PF00082	0.315
CLV_Separin_Metazoa	163	167	PF03568	0.449
DEG_Nend_UBRbox_3	1	3	PF02207	0.505
DEG_SPOP_SBC_1	23	27	PF00917	0.594
DOC_CYCLIN_RxL_1	345	356	PF00134	0.369
DOC_MAPK_gen_1	132	140	PF00069	0.372
DOC_MAPK_HePTP_8	130	142	PF00069	0.373
DOC_MAPK_MEF2A_6	132	141	PF00069	0.325
DOC_MAPK_MEF2A_6	350	359	PF00069	0.250
DOC_PP2B_LxvP_1	402	405	PF13499	0.431
DOC_USP7_MATH_1	181	185	PF00917	0.564
DOC_USP7_MATH_1	193	197	PF00917	0.674
DOC_USP7_MATH_1	329	333	PF00917	0.439
DOC_USP7_MATH_1	339	343	PF00917	0.459
DOC_USP7_MATH_1	6	10	PF00917	0.748
DOC_USP7_UBL2_3	235	239	PF12436	0.398
DOC_WW_Pin1_4	117	122	PF00397	0.411
DOC_WW_Pin1_4	197	202	PF00397	0.681
LIG_14-3-3_CanoR_1	170	175	PF00244	0.418
LIG_14-3-3_CanoR_1	311	317	PF00244	0.295
LIG_14-3-3_CanoR_1	324	329	PF00244	0.348
LIG_14-3-3_CanoR_1	365	373	PF00244	0.298
LIG_APCC_ABBA_1	298	303	PF00400	0.473
LIG_APCC_ABBA_1	373	378	PF00400	0.367
LIG_APCC_ABBAyCdc20_2	372	378	PF00400	0.368
LIG_BIR_III_4	378	382	PF00653	0.235
LIG_BRCT_BRCA1_1	119	123	PF00533	0.320
LIG_FHA_1	313	319	PF00498	0.348
LIG_FHA_1	354	360	PF00498	0.260
LIG_FHA_1	366	372	PF00498	0.283
LIG_FHA_1	54	60	PF00498	0.550
LIG_FHA_2	148	154	PF00498	0.421
LIG_LIR_Nem_3	378	383	PF02991	0.380
LIG_PDZ_Class_3	406	411	PF00595	0.504
LIG_Pex14_2	46	50	PF04695	0.364
LIG_REV1ctd_RIR_1	234	243	PF16727	0.313
LIG_SH2_NCK_1	81	85	PF00017	0.434
LIG_SH2_SRC	261	264	PF00017	0.358
LIG_SH2_SRC	81	84	PF00017	0.398
LIG_SH2_STAP1	232	236	PF00017	0.322
LIG_SH2_STAP1	261	265	PF00017	0.350
LIG_SH2_STAT5	288	291	PF00017	0.446
LIG_SUMO_SIM_par_1	33	38	PF11976	0.531
LIG_TRAF2_1	201	204	PF00917	0.587
LIG_UBA3_1	352	360	PF00899	0.316
LIG_WRC_WIRS_1	171	176	PF05994	0.510
MOD_CK1_1	173	179	PF00069	0.540
MOD_CK1_1	24	30	PF00069	0.598
MOD_CK1_1	55	61	PF00069	0.634
MOD_CK1_1	64	70	PF00069	0.711
MOD_CK2_1	157	163	PF00069	0.524
MOD_CK2_1	188	194	PF00069	0.705
MOD_Cter_Amidation	130	133	PF01082	0.398
MOD_Cter_Amidation	220	223	PF01082	0.345
MOD_GlcNHglycan	158	162	PF01048	0.485
MOD_GlcNHglycan	176	179	PF01048	0.487
MOD_GlcNHglycan	194	198	PF01048	0.490
MOD_GlcNHglycan	27	30	PF01048	0.572
MOD_GlcNHglycan	59	62	PF01048	0.568
MOD_GlcNHglycan	8	12	PF01048	0.767
MOD_GSK3_1	12	19	PF00069	0.670
MOD_GSK3_1	166	173	PF00069	0.421
MOD_GSK3_1	181	188	PF00069	0.391
MOD_GSK3_1	189	196	PF00069	0.544
MOD_GSK3_1	21	28	PF00069	0.586
MOD_GSK3_1	344	351	PF00069	0.359
MOD_GSK3_1	53	60	PF00069	0.635
MOD_GSK3_1	61	68	PF00069	0.628
MOD_N-GLC_1	64	69	PF02516	0.651
MOD_NEK2_1	174	179	PF00069	0.491
MOD_NEK2_1	353	358	PF00069	0.246
MOD_NEK2_1	57	62	PF00069	0.684
MOD_NEK2_1	96	101	PF00069	0.433
MOD_PKA_2	181	187	PF00069	0.550
MOD_PKA_2	329	335	PF00069	0.562
MOD_Plk_1	261	267	PF00069	0.342
MOD_Plk_4	182	188	PF00069	0.415
MOD_Plk_4	35	41	PF00069	0.420
MOD_ProDKin_1	117	123	PF00069	0.410
MOD_ProDKin_1	197	203	PF00069	0.681
MOD_SUMO_rev_2	327	336	PF00179	0.492
TRG_DiLeu_BaLyEn_6	134	139	PF01217	0.327
TRG_ER_diArg_1	110	113	PF00400	0.446
TRG_Pf-PMV_PEXEL_1	390	395	PF00026	0.372

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCP0	Leptomonas seymouri	64%	100%
A0A0S4J7D9	Bodo saltans	38%	100%
A0A1X0NU43	Trypanosomatidae	41%	100%
A0A422N2C4	Trypanosoma rangeli	42%	100%
C9ZSQ1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
V5D4J4	Trypanosoma cruzi	40%	100%