Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ILP4_LEIDO

TriTrypDb:

LdBPK_323760.1 , LdCL_320043600 , LDHU3_32.4760

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ILP4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ILP4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	164	168	PF00656	0.570
CLV_C14_Caspase3-7	79	83	PF00656	0.502
CLV_NRD_NRD_1	109	111	PF00675	0.646
CLV_NRD_NRD_1	59	61	PF00675	0.578
CLV_PCSK_FUR_1	110	114	PF00082	0.441
CLV_PCSK_KEX2_1	109	111	PF00082	0.635
CLV_PCSK_KEX2_1	112	114	PF00082	0.579
CLV_PCSK_KEX2_1	59	61	PF00082	0.578
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.547
CLV_PCSK_SKI1_1	170	174	PF00082	0.626
CLV_PCSK_SKI1_1	177	181	PF00082	0.525
CLV_PCSK_SKI1_1	196	200	PF00082	0.697
CLV_PCSK_SKI1_1	67	71	PF00082	0.592
CLV_Separin_Metazoa	106	110	PF03568	0.666
CLV_Separin_Metazoa	68	72	PF03568	0.661
DEG_APCC_DBOX_1	169	177	PF00400	0.602
DEG_APCC_DBOX_1	66	74	PF00400	0.661
DOC_MAPK_gen_1	32	41	PF00069	0.651
DOC_MAPK_MEF2A_6	71	78	PF00069	0.599
DOC_MAPK_NFAT4_5	71	79	PF00069	0.600
DOC_PP2B_LxvP_1	144	147	PF13499	0.683
DOC_USP7_MATH_1	152	156	PF00917	0.712
DOC_WW_Pin1_4	165	170	PF00397	0.562
LIG_14-3-3_CanoR_1	50	58	PF00244	0.471
LIG_BIR_II_1	1	5	PF00653	0.726
LIG_FHA_1	141	147	PF00498	0.676
LIG_FHA_1	32	38	PF00498	0.631
LIG_FHA_1	98	104	PF00498	0.632
LIG_FHA_2	157	163	PF00498	0.717
LIG_FHA_2	63	69	PF00498	0.631
LIG_FHA_2	77	83	PF00498	0.494
LIG_NRBOX	69	75	PF00104	0.670
LIG_PDZ_Class_2	195	200	PF00595	0.590
LIG_SH2_STAT5	22	25	PF00017	0.681
LIG_TRAF2_1	40	43	PF00917	0.564
MOD_CDK_SPK_2	165	170	PF00069	0.520
MOD_CK1_1	168	174	PF00069	0.612
MOD_CK1_1	2	8	PF00069	0.776
MOD_CK1_1	9	15	PF00069	0.688
MOD_CK2_1	125	131	PF00069	0.548
MOD_CK2_1	156	162	PF00069	0.740
MOD_CK2_1	168	174	PF00069	0.541
MOD_CK2_1	62	68	PF00069	0.634
MOD_GlcNHglycan	10	14	PF01048	0.754
MOD_GlcNHglycan	100	103	PF01048	0.558
MOD_GlcNHglycan	154	157	PF01048	0.743
MOD_GlcNHglycan	170	173	PF01048	0.425
MOD_GlcNHglycan	90	93	PF01048	0.660
MOD_GSK3_1	152	159	PF00069	0.763
MOD_GSK3_1	161	168	PF00069	0.622
MOD_GSK3_1	190	197	PF00069	0.641
MOD_GSK3_1	2	9	PF00069	0.775
MOD_GSK3_1	76	83	PF00069	0.597
MOD_GSK3_1	84	91	PF00069	0.601
MOD_PIKK_1	116	122	PF00454	0.575
MOD_PK_1	125	131	PF00069	0.587
MOD_PKA_2	31	37	PF00069	0.556
MOD_PKA_2	84	90	PF00069	0.571
MOD_Plk_1	187	193	PF00069	0.535
MOD_Plk_4	156	162	PF00069	0.669
MOD_Plk_4	187	193	PF00069	0.496
MOD_ProDKin_1	165	171	PF00069	0.558
MOD_SUMO_for_1	179	182	PF00179	0.638
MOD_SUMO_rev_2	174	181	PF00179	0.598
TRG_ER_diArg_1	108	110	PF00400	0.550
TRG_ER_diArg_1	58	60	PF00400	0.569
TRG_NES_CRM1_1	68	82	PF08389	0.680

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVP8	Leptomonas seymouri	34%	97%
A4HKZ9	Leishmania braziliensis	62%	100%
A4I8I0	Leishmania infantum	100%	100%
E9B3E0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q4R2	Leishmania major	90%	100%