Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, pseudogene

Species:

Leishmania donovani

UniProt:

A0A3Q8ILG5_LEIDO

TriTrypDb:

LdBPK_343430.1 , LdCL_340043700 , LDHU3_34.5660

Length:

107

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 9

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 6

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 3, no: 5
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

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Expansion

Sequence features

A0A3Q8ILG5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ILG5

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	4	6	PF00675	0.663
DEG_SCF_FBW7_2	86	93	PF00400	0.657
DEG_SPOP_SBC_1	23	27	PF00917	0.618
DOC_USP7_UBL2_3	76	80	PF12436	0.716
DOC_WW_Pin1_4	28	33	PF00397	0.440
DOC_WW_Pin1_4	86	91	PF00397	0.678
LIG_APCC_ABBAyCdc20_2	30	36	PF00400	0.394
LIG_BIR_II_1	1	5	PF00653	0.520
LIG_eIF4E_1	58	64	PF01652	0.585
LIG_GBD_Chelix_1	52	60	PF00786	0.410

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P279	Leptomonas seymouri	48%	68%
A0A3S7X8E8	Leishmania donovani	76%	66%
A4HB83	Leishmania braziliensis	61%	100%
A4IAD0	Leishmania infantum	76%	66%
E9AEH7	Leishmania major	72%	98%
E9B5F4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	100%
Q4Q2I0	Leishmania major	60%	66%

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