Flagellum_targeting_protein_kharon1_putative/Gene DB:LmjF.36.5850

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

flagellum targeting protein kharon1, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IL75_LEIDO

TriTrypDb:

LdBPK_366110.1 , LdCL_360068500 , LDHU3_36.8060

Length:

530

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IL75

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IL75

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	121	123	PF00675	0.666
CLV_NRD_NRD_1	152	154	PF00675	0.623
CLV_NRD_NRD_1	22	24	PF00675	0.576
CLV_NRD_NRD_1	290	292	PF00675	0.651
CLV_NRD_NRD_1	300	302	PF00675	0.580
CLV_NRD_NRD_1	393	395	PF00675	0.647
CLV_NRD_NRD_1	47	49	PF00675	0.682
CLV_NRD_NRD_1	84	86	PF00675	0.702
CLV_PCSK_KEX2_1	121	123	PF00082	0.666
CLV_PCSK_KEX2_1	141	143	PF00082	0.637
CLV_PCSK_KEX2_1	154	156	PF00082	0.558
CLV_PCSK_KEX2_1	220	222	PF00082	0.692
CLV_PCSK_KEX2_1	393	395	PF00082	0.647
CLV_PCSK_KEX2_1	448	450	PF00082	0.828
CLV_PCSK_KEX2_1	47	49	PF00082	0.682
CLV_PCSK_KEX2_1	491	493	PF00082	0.803
CLV_PCSK_KEX2_1	84	86	PF00082	0.702
CLV_PCSK_PC1ET2_1	141	143	PF00082	0.593
CLV_PCSK_PC1ET2_1	154	156	PF00082	0.542
CLV_PCSK_PC1ET2_1	220	222	PF00082	0.692
CLV_PCSK_PC1ET2_1	448	450	PF00082	0.828
CLV_PCSK_PC1ET2_1	491	493	PF00082	0.638
CLV_PCSK_PC7_1	444	450	PF00082	0.561
CLV_PCSK_SKI1_1	228	232	PF00082	0.658
CLV_PCSK_SKI1_1	462	466	PF00082	0.728
CLV_PCSK_SKI1_1	67	71	PF00082	0.600
CLV_PCSK_SKI1_1	78	82	PF00082	0.682
DOC_CKS1_1	309	314	PF01111	0.616
DOC_CKS1_1	506	511	PF01111	0.564
DOC_MAPK_gen_1	521	529	PF00069	0.629
DOC_MAPK_MEF2A_6	33	40	PF00069	0.553
DOC_MAPK_NFAT4_5	33	41	PF00069	0.557
DOC_PP4_FxxP_1	63	66	PF00568	0.674
DOC_PP4_FxxP_1	70	73	PF00568	0.559
DOC_USP7_MATH_1	261	265	PF00917	0.566
DOC_USP7_MATH_1	367	371	PF00917	0.674
DOC_USP7_MATH_1	41	45	PF00917	0.572
DOC_USP7_MATH_1	428	432	PF00917	0.680
DOC_USP7_MATH_1	71	75	PF00917	0.518
DOC_USP7_UBL2_3	150	154	PF12436	0.587
DOC_USP7_UBL2_3	256	260	PF12436	0.644
DOC_WW_Pin1_4	14	19	PF00397	0.536
DOC_WW_Pin1_4	3	8	PF00397	0.705
DOC_WW_Pin1_4	308	313	PF00397	0.615
DOC_WW_Pin1_4	324	329	PF00397	0.524
DOC_WW_Pin1_4	418	423	PF00397	0.643
DOC_WW_Pin1_4	442	447	PF00397	0.695
DOC_WW_Pin1_4	505	510	PF00397	0.567
DOC_WW_Pin1_4	62	67	PF00397	0.609
LIG_14-3-3_CanoR_1	121	130	PF00244	0.597
LIG_14-3-3_CanoR_1	291	296	PF00244	0.576
LIG_14-3-3_CanoR_1	418	422	PF00244	0.641
LIG_14-3-3_CanoR_1	60	66	PF00244	0.597
LIG_14-3-3_CanoR_1	9	13	PF00244	0.714
LIG_BIR_III_2	213	217	PF00653	0.595
LIG_EVH1_2	76	80	PF00568	0.593
LIG_FHA_1	161	167	PF00498	0.537
LIG_FHA_1	345	351	PF00498	0.658
LIG_FHA_1	404	410	PF00498	0.575
LIG_FHA_1	506	512	PF00498	0.549
LIG_FHA_2	103	109	PF00498	0.685
LIG_FHA_2	177	183	PF00498	0.602
LIG_FHA_2	272	278	PF00498	0.571
LIG_LIR_Apic_2	322	328	PF02991	0.672
LIG_LIR_Apic_2	68	73	PF02991	0.578
LIG_MYND_1	296	300	PF01753	0.539
LIG_PCNA_yPIPBox_3	466	478	PF02747	0.553
LIG_SH2_STAT3	136	139	PF00017	0.598
LIG_SH2_STAT3	410	413	PF00017	0.598
LIG_SH2_STAT5	102	105	PF00017	0.560
LIG_SH2_STAT5	202	205	PF00017	0.675
LIG_SH2_STAT5	273	276	PF00017	0.572
LIG_SH2_STAT5	463	466	PF00017	0.534
LIG_SH3_2	181	186	PF14604	0.603
LIG_SH3_2	296	301	PF14604	0.541
LIG_SH3_2	73	78	PF14604	0.572
LIG_SH3_3	175	181	PF00018	0.614
LIG_SH3_3	205	211	PF00018	0.653
LIG_SH3_3	220	226	PF00018	0.498
LIG_SH3_3	233	239	PF00018	0.617
LIG_SH3_3	293	299	PF00018	0.548
LIG_SH3_3	302	308	PF00018	0.556
LIG_SH3_3	487	493	PF00018	0.600
LIG_SH3_3	70	76	PF00018	0.642
LIG_SUMO_SIM_anti_2	263	269	PF11976	0.592
LIG_TRAF2_1	238	241	PF00917	0.686
LIG_TRAF2_1	313	316	PF00917	0.628
LIG_WW_3	209	213	PF00397	0.653
LIG_WW_3	298	302	PF00397	0.573
LIG_WW_3	57	61	PF00397	0.603
LIG_WW_3	75	79	PF00397	0.475
MOD_CDC14_SPxK_1	327	330	PF00782	0.542
MOD_CDC14_SPxK_1	445	448	PF00782	0.631
MOD_CDC14_SPxK_1	6	9	PF00782	0.638
MOD_CDK_SPK_2	14	19	PF00069	0.518
MOD_CDK_SPK_2	442	447	PF00069	0.585
MOD_CDK_SPK_2	62	67	PF00069	0.609
MOD_CDK_SPxK_1	3	9	PF00069	0.641
MOD_CDK_SPxK_1	308	314	PF00069	0.617
MOD_CDK_SPxK_1	324	330	PF00069	0.522
MOD_CDK_SPxK_1	442	448	PF00069	0.604
MOD_CDK_SPxxK_3	14	21	PF00069	0.511
MOD_CDK_SPxxK_3	418	425	PF00069	0.634
MOD_CDK_SPxxK_3	442	449	PF00069	0.678
MOD_CK1_1	110	116	PF00069	0.639
MOD_CK1_1	124	130	PF00069	0.589
MOD_CK1_1	370	376	PF00069	0.639
MOD_CK1_1	379	385	PF00069	0.636
MOD_CK1_1	392	398	PF00069	0.620
MOD_CK1_1	403	409	PF00069	0.582
MOD_CK1_1	421	427	PF00069	0.621
MOD_CK1_1	523	529	PF00069	0.691
MOD_CK1_1	93	99	PF00069	0.429
MOD_CK2_1	176	182	PF00069	0.653
MOD_CK2_1	271	277	PF00069	0.578
MOD_CK2_1	291	297	PF00069	0.574
MOD_CK2_1	494	500	PF00069	0.674
MOD_CK2_1	62	68	PF00069	0.604
MOD_Cter_Amidation	218	221	PF01082	0.685
MOD_DYRK1A_RPxSP_1	418	422	PF00069	0.571
MOD_DYRK1A_RPxSP_1	442	446	PF00069	0.585
MOD_GlcNHglycan	115	118	PF01048	0.620
MOD_GlcNHglycan	132	135	PF01048	0.589
MOD_GlcNHglycan	26	29	PF01048	0.576
MOD_GlcNHglycan	293	296	PF01048	0.569
MOD_GlcNHglycan	378	381	PF01048	0.605
MOD_GlcNHglycan	398	401	PF01048	0.526
MOD_GlcNHglycan	402	405	PF01048	0.601
MOD_GlcNHglycan	43	46	PF01048	0.490
MOD_GSK3_1	103	110	PF00069	0.498
MOD_GSK3_1	370	377	PF00069	0.635
MOD_GSK3_1	392	399	PF00069	0.630
MOD_GSK3_1	417	424	PF00069	0.629
MOD_GSK3_1	438	445	PF00069	0.718
MOD_GSK3_1	494	501	PF00069	0.729
MOD_N-GLC_1	24	29	PF02516	0.559
MOD_N-GLC_1	261	266	PF02516	0.603
MOD_N-GLC_1	61	66	PF02516	0.568
MOD_N-GLC_2	174	176	PF02516	0.626
MOD_NEK2_1	246	251	PF00069	0.621
MOD_NEK2_1	454	459	PF00069	0.536
MOD_PIKK_1	135	141	PF00454	0.608
MOD_PK_1	155	161	PF00069	0.635
MOD_PK_1	398	404	PF00069	0.577
MOD_PKA_1	121	127	PF00069	0.620
MOD_PKA_1	291	297	PF00069	0.574
MOD_PKA_2	121	127	PF00069	0.649
MOD_PKA_2	392	398	PF00069	0.651
MOD_PKA_2	417	423	PF00069	0.651
MOD_PKA_2	428	434	PF00069	0.646
MOD_PKA_2	523	529	PF00069	0.626
MOD_PKA_2	8	14	PF00069	0.716
MOD_PKA_2	90	96	PF00069	0.632
MOD_PKB_1	153	161	PF00069	0.632
MOD_Plk_1	107	113	PF00069	0.589
MOD_Plk_1	261	267	PF00069	0.652
MOD_Plk_1	454	460	PF00069	0.670
MOD_Plk_4	93	99	PF00069	0.528
MOD_ProDKin_1	14	20	PF00069	0.533
MOD_ProDKin_1	3	9	PF00069	0.707
MOD_ProDKin_1	308	314	PF00069	0.617
MOD_ProDKin_1	324	330	PF00069	0.522
MOD_ProDKin_1	418	424	PF00069	0.645
MOD_ProDKin_1	442	448	PF00069	0.695
MOD_ProDKin_1	505	511	PF00069	0.567
MOD_ProDKin_1	62	68	PF00069	0.604
MOD_SUMO_for_1	313	316	PF00179	0.584
MOD_SUMO_rev_2	497	503	PF00179	0.612
TRG_ER_diArg_1	120	122	PF00400	0.610
TRG_ER_diArg_1	166	169	PF00400	0.555
TRG_ER_diArg_1	18	21	PF00400	0.507
TRG_ER_diArg_1	47	49	PF00400	0.638
TRG_ER_diArg_1	83	85	PF00400	0.714
TRG_NLS_Bipartite_1	141	157	PF00514	0.578
TRG_NLS_MonoExtC_3	149	154	PF00514	0.586
TRG_NLS_MonoExtN_4	148	154	PF00514	0.641
TRG_NLS_MonoExtN_4	21	27	PF00514	0.558

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HQA3	Leishmania braziliensis	64%	96%
A4IDZ8	Leishmania infantum	100%	100%
E9AU20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	98%
Q4Q0H5	Leishmania major	77%	100%