LeishMANIAdb
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Phosphoprotein_lepp12/GeneDB:LmjF.36.5720

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Phosphoprotein_lepp12/GeneDB:LmjF.36.5720
Gene product:
phosphoprotein lepp12
Species:
Leishmania donovani
UniProt:
A0A3Q8IL65_LEIDO
TriTrypDb:
LdBPK_365970.1 , LdCL_360067100 , LDHU3_36.7890
Length:
88

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IL65
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IL65

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 12 14 PF00675 0.566
CLV_NRD_NRD_1 21 23 PF00675 0.539
CLV_NRD_NRD_1 62 64 PF00675 0.589
CLV_PCSK_KEX2_1 12 14 PF00082 0.566
CLV_PCSK_KEX2_1 3 5 PF00082 0.569
CLV_PCSK_KEX2_1 33 35 PF00082 0.523
CLV_PCSK_KEX2_1 75 77 PF00082 0.687
CLV_PCSK_PC1ET2_1 12 14 PF00082 0.566
CLV_PCSK_PC1ET2_1 3 5 PF00082 0.569
CLV_PCSK_PC1ET2_1 33 35 PF00082 0.523
CLV_PCSK_PC1ET2_1 75 77 PF00082 0.626
CLV_PCSK_SKI1_1 22 26 PF00082 0.499
CLV_PCSK_SKI1_1 56 60 PF00082 0.640
CLV_PCSK_SKI1_1 83 87 PF00082 0.675
DEG_APCC_DBOX_1 33 41 PF00400 0.524
DOC_PP1_RVXF_1 41 48 PF00149 0.663
DOC_USP7_UBL2_3 10 14 PF12436 0.526
DOC_USP7_UBL2_3 23 27 PF12436 0.535
DOC_USP7_UBL2_3 29 33 PF12436 0.537
DOC_USP7_UBL2_3 3 7 PF12436 0.562
LIG_14-3-3_CanoR_1 22 30 PF00244 0.596
LIG_14-3-3_CanoR_1 43 48 PF00244 0.642
LIG_FHA_2 67 73 PF00498 0.708
LIG_Integrin_RGD_1 34 36 PF01839 0.516
LIG_SH2_STAT5 84 87 PF00017 0.655
MOD_Cter_Amidation 1 4 PF01082 0.614
MOD_GSK3_1 39 46 PF00069 0.681
MOD_N-GLC_1 43 48 PF02516 0.664
MOD_NEK2_1 39 44 PF00069 0.624
MOD_PKA_1 22 28 PF00069 0.528
MOD_PKB_1 20 28 PF00069 0.500
MOD_Plk_1 43 49 PF00069 0.596
TRG_ER_diArg_1 81 84 PF00400 0.658
TRG_NLS_MonoExtC_3 2 7 PF00514 0.562
TRG_NLS_MonoExtN_4 9 16 PF00514 0.575

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4J235 Bodo saltans 75% 81%
A0A6L0XUA8 Leishmania infantum 100% 100%
A4HQ88 Leishmania braziliensis 93% 100%
C9ZT84 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 66% 100%
E9AU06 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
Q9N861 Leishmania major 98% 100%
V5BJ70 Trypanosoma cruzi 76% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS