IQ calmodulin-binding motif containing protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IL14_LEIDO

TriTrypDb:

LdBPK_341780.1 , LdCL_340025400 , LDHU3_34.3070

Length:

1171

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IL14

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IL14

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0005515	protein binding	2	1
GO:0005516	calmodulin binding	3	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	303	307	PF00656	0.653
CLV_C14_Caspase3-7	316	320	PF00656	0.655
CLV_C14_Caspase3-7	322	326	PF00656	0.572
CLV_C14_Caspase3-7	416	420	PF00656	0.537
CLV_C14_Caspase3-7	688	692	PF00656	0.496
CLV_MEL_PAP_1	425	431	PF00089	0.559
CLV_NRD_NRD_1	1005	1007	PF00675	0.485
CLV_NRD_NRD_1	1035	1037	PF00675	0.601
CLV_NRD_NRD_1	1091	1093	PF00675	0.677
CLV_NRD_NRD_1	1106	1108	PF00675	0.470

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8X5	Leptomonas seymouri	43%	95%
A4HAR6	Leishmania braziliensis	63%	99%
A4I9Y0	Leishmania infantum	99%	100%
E9B4Y8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q2Z8	Leishmania major	88%	100%

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