CID domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IL02_LEIDO

TriTrypDb:

LdBPK_210640.1 , LdCL_210011400 , LDHU3_21.0690

Length:

464

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IL02

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IL02

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	120	122	PF00675	0.532
CLV_NRD_NRD_1	125	127	PF00675	0.565
CLV_NRD_NRD_1	273	275	PF00675	0.596
CLV_NRD_NRD_1	382	384	PF00675	0.620
CLV_NRD_NRD_1	456	458	PF00675	0.598
CLV_PCSK_KEX2_1	120	122	PF00082	0.440
CLV_PCSK_KEX2_1	125	127	PF00082	0.472
CLV_PCSK_KEX2_1	273	275	PF00082	0.596
CLV_PCSK_KEX2_1	458	460	PF00082	0.630
CLV_PCSK_PC1ET2_1	458	460	PF00082	0.630
CLV_PCSK_PC7_1	121	127	PF00082	0.516
CLV_PCSK_SKI1_1	241	245	PF00082	0.592
CLV_PCSK_SKI1_1	274	278	PF00082	0.574
CLV_PCSK_SKI1_1	368	372	PF00082	0.709
CLV_PCSK_SKI1_1	450	454	PF00082	0.741
CLV_Separin_Metazoa	247	251	PF03568	0.609
DEG_APCC_DBOX_1	308	316	PF00400	0.699
DEG_COP1_1	205	213	PF00400	0.541
DEG_Nend_UBRbox_2	1	3	PF02207	0.453
DEG_SCF_FBW7_1	210	216	PF00400	0.633
DEG_SPOP_SBC_1	166	170	PF00917	0.673
DEG_SPOP_SBC_1	178	182	PF00917	0.633
DEG_SPOP_SBC_1	279	283	PF00917	0.720
DEG_SPOP_SBC_1	75	79	PF00917	0.652
DOC_CKS1_1	210	215	PF01111	0.645
DOC_MAPK_MEF2A_6	241	248	PF00069	0.482
DOC_MAPK_NFAT4_5	241	249	PF00069	0.504
DOC_PP1_RVXF_1	424	430	PF00149	0.699
DOC_PP4_FxxP_1	254	257	PF00568	0.612
DOC_PP4_FxxP_1	412	415	PF00568	0.592
DOC_PP4_MxPP_1	201	204	PF00568	0.469
DOC_USP7_MATH_1	166	170	PF00917	0.745
DOC_USP7_MATH_1	179	183	PF00917	0.617
DOC_USP7_MATH_1	185	189	PF00917	0.758
DOC_USP7_MATH_1	204	208	PF00917	0.633
DOC_USP7_MATH_1	211	215	PF00917	0.644
DOC_USP7_MATH_1	222	226	PF00917	0.353
DOC_USP7_MATH_1	279	283	PF00917	0.714
DOC_USP7_MATH_1	73	77	PF00917	0.681
DOC_USP7_MATH_1	99	103	PF00917	0.518
DOC_USP7_UBL2_3	142	146	PF12436	0.609
DOC_WW_Pin1_4	183	188	PF00397	0.696
DOC_WW_Pin1_4	209	214	PF00397	0.677
DOC_WW_Pin1_4	280	285	PF00397	0.640
DOC_WW_Pin1_4	356	361	PF00397	0.572
DOC_WW_Pin1_4	71	76	PF00397	0.670
LIG_14-3-3_CanoR_1	221	231	PF00244	0.635
LIG_14-3-3_CanoR_1	259	263	PF00244	0.551
LIG_14-3-3_CanoR_1	47	53	PF00244	0.539
LIG_APCC_ABBAyCdc20_2	241	247	PF00400	0.485
LIG_BRCT_BRCA1_1	250	254	PF00533	0.661
LIG_BRCT_BRCA1_1	260	264	PF00533	0.466
LIG_BRCT_BRCA1_1	358	362	PF00533	0.624
LIG_deltaCOP1_diTrp_1	91	100	PF00928	0.406
LIG_EH1_1	56	64	PF00400	0.389
LIG_FHA_1	132	138	PF00498	0.531
LIG_FHA_1	350	356	PF00498	0.641
LIG_FHA_2	136	142	PF00498	0.488
LIG_FHA_2	5	11	PF00498	0.558
LIG_FHA_2	75	81	PF00498	0.637
LIG_LIR_Apic_2	205	211	PF02991	0.549
LIG_LIR_Apic_2	251	257	PF02991	0.658
LIG_LIR_Gen_1	359	370	PF02991	0.624
LIG_LIR_Nem_3	359	365	PF02991	0.615
LIG_LIR_Nem_3	376	381	PF02991	0.641
LIG_LIR_Nem_3	394	400	PF02991	0.715
LIG_LIR_Nem_3	54	60	PF02991	0.394
LIG_LIR_Nem_3	91	95	PF02991	0.404
LIG_NRBOX	311	317	PF00104	0.566
LIG_PDZ_Class_3	459	464	PF00595	0.754
LIG_SH2_CRK	208	212	PF00017	0.543
LIG_SH2_NCK_1	208	212	PF00017	0.543
LIG_SH2_PTP2	357	360	PF00017	0.673
LIG_SH2_STAP1	366	370	PF00017	0.693
LIG_SH2_STAP1	397	401	PF00017	0.662
LIG_SH2_STAT3	366	369	PF00017	0.693
LIG_SH2_STAT5	245	248	PF00017	0.505
LIG_SH2_STAT5	357	360	PF00017	0.617
LIG_SH2_STAT5	397	400	PF00017	0.659
LIG_SH3_3	125	131	PF00018	0.600
LIG_SH3_3	207	213	PF00018	0.676
LIG_UBA3_1	136	142	PF00899	0.445
MOD_CDC14_SPxK_1	283	286	PF00782	0.555
MOD_CDK_SPxK_1	280	286	PF00069	0.534
MOD_CK1_1	160	166	PF00069	0.686
MOD_CK1_1	169	175	PF00069	0.623
MOD_CK1_1	186	192	PF00069	0.660
MOD_CK1_1	209	215	PF00069	0.658
MOD_CK1_1	258	264	PF00069	0.613
MOD_CK1_1	280	286	PF00069	0.640
MOD_CK1_1	349	355	PF00069	0.741
MOD_CK1_1	391	397	PF00069	0.746
MOD_CK1_1	74	80	PF00069	0.637
MOD_CK2_1	135	141	PF00069	0.443
MOD_CK2_1	229	235	PF00069	0.534
MOD_CK2_1	4	10	PF00069	0.546
MOD_CK2_1	74	80	PF00069	0.650
MOD_Cter_Amidation	455	458	PF01082	0.689
MOD_GlcNHglycan	181	184	PF01048	0.684
MOD_GlcNHglycan	204	207	PF01048	0.699
MOD_GlcNHglycan	26	29	PF01048	0.472
MOD_GlcNHglycan	288	291	PF01048	0.703
MOD_GlcNHglycan	330	333	PF01048	0.701
MOD_GlcNHglycan	348	351	PF01048	0.447
MOD_GlcNHglycan	390	393	PF01048	0.757
MOD_GlcNHglycan	71	74	PF01048	0.617
MOD_GSK3_1	131	138	PF00069	0.536
MOD_GSK3_1	153	160	PF00069	0.706
MOD_GSK3_1	161	168	PF00069	0.627
MOD_GSK3_1	179	186	PF00069	0.587
MOD_GSK3_1	187	194	PF00069	0.766
MOD_GSK3_1	202	209	PF00069	0.711
MOD_GSK3_1	229	236	PF00069	0.513
MOD_GSK3_1	274	281	PF00069	0.606
MOD_GSK3_1	346	353	PF00069	0.621
MOD_GSK3_1	356	363	PF00069	0.507
MOD_GSK3_1	373	380	PF00069	0.664
MOD_GSK3_1	391	398	PF00069	0.442
MOD_GSK3_1	442	449	PF00069	0.685
MOD_GSK3_1	63	70	PF00069	0.502
MOD_GSK3_1	71	78	PF00069	0.595
MOD_LATS_1	253	259	PF00433	0.613
MOD_N-GLC_1	160	165	PF02516	0.704
MOD_NEK2_1	223	228	PF00069	0.577
MOD_NEK2_1	248	253	PF00069	0.648
MOD_NEK2_1	278	283	PF00069	0.585
MOD_NEK2_1	396	401	PF00069	0.652
MOD_NEK2_1	63	68	PF00069	0.489
MOD_NEK2_2	99	104	PF00069	0.532
MOD_PIKK_1	248	254	PF00454	0.645
MOD_PIKK_1	442	448	PF00454	0.693
MOD_PKA_1	457	463	PF00069	0.701
MOD_PKA_2	12	18	PF00069	0.645
MOD_PKA_2	223	229	PF00069	0.557
MOD_PKA_2	258	264	PF00069	0.589
MOD_PKA_2	308	314	PF00069	0.699
MOD_PKA_2	373	379	PF00069	0.682
MOD_PKA_2	46	52	PF00069	0.547
MOD_PKB_1	455	463	PF00069	0.696
MOD_Plk_1	274	280	PF00069	0.626
MOD_Plk_1	442	448	PF00069	0.650
MOD_Plk_1	63	69	PF00069	0.494
MOD_Plk_4	350	356	PF00069	0.705
MOD_Plk_4	396	402	PF00069	0.671
MOD_ProDKin_1	183	189	PF00069	0.698
MOD_ProDKin_1	209	215	PF00069	0.665
MOD_ProDKin_1	280	286	PF00069	0.646
MOD_ProDKin_1	356	362	PF00069	0.570
MOD_ProDKin_1	71	77	PF00069	0.673
MOD_SUMO_for_1	145	148	PF00179	0.722
MOD_SUMO_for_1	402	405	PF00179	0.682
TRG_DiLeu_BaLyEn_6	128	133	PF01217	0.532
TRG_ENDOCYTIC_2	245	248	PF00928	0.469
TRG_ER_diArg_1	119	121	PF00400	0.535
TRG_ER_diArg_1	125	127	PF00400	0.565
TRG_ER_diArg_1	272	274	PF00400	0.578
TRG_NES_CRM1_1	310	325	PF08389	0.621
TRG_NLS_MonoExtC_3	456	461	PF00514	0.694
TRG_NLS_MonoExtN_4	455	461	PF00514	0.693
TRG_Pf-PMV_PEXEL_1	125	130	PF00026	0.523
TRG_Pf-PMV_PEXEL_1	450	454	PF00026	0.741

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P858	Leptomonas seymouri	53%	100%
A0A1X0NY71	Trypanosomatidae	28%	100%
A0A422NH97	Trypanosoma rangeli	31%	100%
A4HBQ5	Leishmania braziliensis	81%	99%
A4HZ57	Leishmania infantum	99%	100%
D0A1I3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9AV25	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	99%
Q4QCF7	Leishmania major	94%	100%
V5DEP6	Trypanosoma cruzi	31%	100%