40S ribosomal protein S24

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S24e

Species:

Leishmania donovani

UniProt:

A0A3Q8IKW0_LEIDO

TriTrypDb:

LdBPK_363020.1 , LdCL_360036500 , LdCL_360036600 , LDHU3_36.4170 , LDHU3_36.4180

Length:

137

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 40S ribosomal S24 S24E-1

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 21

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 21

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005840	ribosome	5	11
GO:0032991	protein-containing complex	1	11
GO:0043226	organelle	2	11
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043232	intracellular non-membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11
GO:1990904	ribonucleoprotein complex	2	11

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Expansion

Sequence features

A0A3Q8IKW0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IKW0

PDB structure(s): 6az1_Z

Function

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Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	11
GO:0006518	peptide metabolic process	4	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009058	biosynthetic process	2	11
GO:0009059	macromolecule biosynthetic process	4	11
GO:0009987	cellular process	1	11
GO:0019538	protein metabolic process	3	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	11

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Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	11
GO:0005198	structural molecule activity	1	11

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	110	112	PF00675	0.499
CLV_NRD_NRD_1	117	119	PF00675	0.513
CLV_NRD_NRD_1	24	26	PF00675	0.407
CLV_NRD_NRD_1	46	48	PF00675	0.443
CLV_NRD_NRD_1	96	98	PF00675	0.335
CLV_PCSK_KEX2_1	117	119	PF00082	0.523
CLV_PCSK_KEX2_1	90	92	PF00082	0.335
CLV_PCSK_PC1ET2_1	90	92	PF00082	0.335
CLV_PCSK_SKI1_1	112	116	PF00082	0.488
CLV_PCSK_SKI1_1	49	53	PF00082	0.430

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P792	Leptomonas seymouri	94%	100%
A0A0S4IT08	Bodo saltans	79%	100%
A0A1X0NL68	Trypanosomatidae	82%	100%
A0A3R7MID6	Trypanosoma rangeli	82%	100%
A4HPF3	Leishmania braziliensis	93%	100%
A4ID74	Leishmania infantum	100%	100%
D0A3G5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	81%	100%
E9AT64	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
O13784	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	47%	100%
O42387	Takifugu rubripes	50%	100%

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