UDENN domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IKU6_LEIDO

TriTrypDb:

LdBPK_320880.1 , LdCL_320014300 , LDHU3_32.1120

Length:

466

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IKU6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IKU6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	373	377	PF00656	0.623
CLV_C14_Caspase3-7	400	404	PF00656	0.636
CLV_NRD_NRD_1	114	116	PF00675	0.391
CLV_NRD_NRD_1	188	190	PF00675	0.340
CLV_NRD_NRD_1	193	195	PF00675	0.382
CLV_NRD_NRD_1	262	264	PF00675	0.470
CLV_PCSK_KEX2_1	114	116	PF00082	0.391
CLV_PCSK_KEX2_1	187	189	PF00082	0.342
CLV_PCSK_KEX2_1	192	194	PF00082	0.381
CLV_PCSK_PC7_1	188	194	PF00082	0.362
CLV_PCSK_SKI1_1	114	118	PF00082	0.453
CLV_PCSK_SKI1_1	194	198	PF00082	0.566
CLV_PCSK_SKI1_1	450	454	PF00082	0.555
CLV_PCSK_SKI1_1	67	71	PF00082	0.455
DEG_APCC_DBOX_1	113	121	PF00400	0.273
DEG_APCC_DBOX_1	193	201	PF00400	0.482
DEG_ODPH_VHL_1	173	185	PF01847	0.396
DEG_SCF_FBW7_1	342	349	PF00400	0.642
DEG_SPOP_SBC_1	203	207	PF00917	0.559
DEG_SPOP_SBC_1	366	370	PF00917	0.700
DOC_CKS1_1	343	348	PF01111	0.646
DOC_CKS1_1	456	461	PF01111	0.565
DOC_MAPK_gen_1	114	121	PF00069	0.386
DOC_MAPK_gen_1	177	185	PF00069	0.418
DOC_MAPK_gen_1	187	197	PF00069	0.419
DOC_MAPK_MEF2A_6	114	121	PF00069	0.386
DOC_PP1_RVXF_1	124	131	PF00149	0.452
DOC_PP4_FxxP_1	152	155	PF00568	0.419
DOC_PP4_FxxP_1	285	288	PF00568	0.545
DOC_PP4_FxxP_1	289	292	PF00568	0.575
DOC_PP4_FxxP_1	456	459	PF00568	0.576
DOC_PP4_FxxP_1	77	80	PF00568	0.433
DOC_USP7_MATH_1	203	207	PF00917	0.575
DOC_USP7_MATH_1	212	216	PF00917	0.488
DOC_USP7_MATH_1	22	26	PF00917	0.647
DOC_USP7_MATH_1	292	296	PF00917	0.625
DOC_USP7_MATH_1	322	326	PF00917	0.611
DOC_USP7_MATH_1	337	341	PF00917	0.636
DOC_USP7_MATH_1	351	355	PF00917	0.600
DOC_USP7_MATH_1	397	401	PF00917	0.623
DOC_USP7_MATH_1	95	99	PF00917	0.567
DOC_USP7_MATH_2	313	319	PF00917	0.648
DOC_WW_Pin1_4	100	105	PF00397	0.504
DOC_WW_Pin1_4	165	170	PF00397	0.746
DOC_WW_Pin1_4	178	183	PF00397	0.416
DOC_WW_Pin1_4	18	23	PF00397	0.767
DOC_WW_Pin1_4	296	301	PF00397	0.721
DOC_WW_Pin1_4	338	343	PF00397	0.693
DOC_WW_Pin1_4	390	395	PF00397	0.609
DOC_WW_Pin1_4	417	422	PF00397	0.579
DOC_WW_Pin1_4	455	460	PF00397	0.562
DOC_WW_Pin1_4	5	10	PF00397	0.669
LIG_14-3-3_CanoR_1	114	120	PF00244	0.481
LIG_14-3-3_CanoR_1	15	22	PF00244	0.632
LIG_14-3-3_CanoR_1	450	459	PF00244	0.606
LIG_14-3-3_CanoR_1	67	75	PF00244	0.461
LIG_BIR_II_1	1	5	PF00653	0.665
LIG_deltaCOP1_diTrp_1	50	57	PF00928	0.318
LIG_EH_1	286	290	PF12763	0.553
LIG_FHA_1	116	122	PF00498	0.431
LIG_FHA_1	205	211	PF00498	0.622
LIG_FHA_1	44	50	PF00498	0.413
LIG_FHA_2	343	349	PF00498	0.723
LIG_FHA_2	383	389	PF00498	0.688
LIG_FHA_2	391	397	PF00498	0.808
LIG_FHA_2	443	449	PF00498	0.558
LIG_FHA_2	9	15	PF00498	0.594
LIG_LIR_Apic_2	150	155	PF02991	0.427
LIG_LIR_Apic_2	284	288	PF02991	0.546
LIG_LIR_Apic_2	454	459	PF02991	0.572
LIG_LIR_Gen_1	46	53	PF02991	0.360
LIG_LIR_Gen_1	93	104	PF02991	0.480
LIG_LIR_Nem_3	446	452	PF02991	0.564
LIG_LIR_Nem_3	93	99	PF02991	0.466
LIG_LYPXL_yS_3	58	61	PF13949	0.567
LIG_NBox_RRM_1	317	327	PF00076	0.638
LIG_Pex14_2	285	289	PF04695	0.576
LIG_Pex14_2	449	453	PF04695	0.551
LIG_Pex14_2	92	96	PF04695	0.472
LIG_PTB_Apo_2	279	286	PF02174	0.546
LIG_SH2_STAP1	367	371	PF00017	0.673
LIG_SH2_STAT3	148	151	PF00017	0.403
LIG_SH2_STAT5	222	225	PF00017	0.479
LIG_SH3_2	109	114	PF14604	0.436
LIG_SH3_3	106	112	PF00018	0.408
LIG_SH3_3	116	122	PF00018	0.280
LIG_SH3_3	169	175	PF00018	0.535
LIG_SH3_3	197	203	PF00018	0.547
LIG_SH3_3	336	342	PF00018	0.686
LIG_SH3_3	418	424	PF00018	0.586
LIG_SH3_3	96	102	PF00018	0.497
LIG_TRAF2_1	258	261	PF00917	0.438
LIG_TRAF2_1	385	388	PF00917	0.662
LIG_WW_1	79	82	PF00397	0.354
MOD_CDC14_SPxK_1	21	24	PF00782	0.650
MOD_CDK_SPxK_1	18	24	PF00069	0.656
MOD_CDK_SPxxK_3	5	12	PF00069	0.589
MOD_CK1_1	103	109	PF00069	0.452
MOD_CK1_1	2	8	PF00069	0.675
MOD_CK1_1	221	227	PF00069	0.616
MOD_CK1_1	25	31	PF00069	0.622
MOD_CK1_1	354	360	PF00069	0.644
MOD_CK1_1	392	398	PF00069	0.655
MOD_CK1_1	419	425	PF00069	0.600
MOD_CK2_1	221	227	PF00069	0.471
MOD_CK2_1	346	352	PF00069	0.834
MOD_CK2_1	382	388	PF00069	0.661
MOD_CK2_1	392	398	PF00069	0.582
MOD_GlcNHglycan	24	27	PF01048	0.671
MOD_GlcNHglycan	273	276	PF01048	0.459
MOD_GlcNHglycan	317	320	PF01048	0.607
MOD_GlcNHglycan	352	356	PF01048	0.594
MOD_GlcNHglycan	459	462	PF01048	0.597
MOD_GSK3_1	16	23	PF00069	0.656
MOD_GSK3_1	24	31	PF00069	0.625
MOD_GSK3_1	273	280	PF00069	0.526
MOD_GSK3_1	292	299	PF00069	0.629
MOD_GSK3_1	338	345	PF00069	0.671
MOD_GSK3_1	347	354	PF00069	0.664
MOD_GSK3_1	366	373	PF00069	0.658
MOD_GSK3_1	4	11	PF00069	0.739
MOD_GSK3_1	430	437	PF00069	0.593
MOD_GSK3_1	451	458	PF00069	0.547
MOD_GSK3_1	63	70	PF00069	0.451
MOD_NEK2_1	176	181	PF00069	0.410
MOD_NEK2_1	389	394	PF00069	0.755
MOD_NEK2_1	416	421	PF00069	0.591
MOD_NEK2_2	292	297	PF00069	0.575
MOD_PIKK_1	248	254	PF00454	0.559
MOD_PIKK_1	451	457	PF00454	0.562
MOD_PKA_2	271	277	PF00069	0.502
MOD_PKA_2	327	333	PF00069	0.601
MOD_Plk_4	115	121	PF00069	0.292
MOD_Plk_4	218	224	PF00069	0.535
MOD_Plk_4	322	328	PF00069	0.606
MOD_Plk_4	43	49	PF00069	0.439
MOD_ProDKin_1	100	106	PF00069	0.499
MOD_ProDKin_1	165	171	PF00069	0.734
MOD_ProDKin_1	178	184	PF00069	0.404
MOD_ProDKin_1	18	24	PF00069	0.769
MOD_ProDKin_1	296	302	PF00069	0.720
MOD_ProDKin_1	338	344	PF00069	0.693
MOD_ProDKin_1	390	396	PF00069	0.610
MOD_ProDKin_1	417	423	PF00069	0.582
MOD_ProDKin_1	455	461	PF00069	0.563
MOD_ProDKin_1	5	11	PF00069	0.673
TRG_ENDOCYTIC_2	125	128	PF00928	0.377
TRG_ENDOCYTIC_2	58	61	PF00928	0.567
TRG_ER_diArg_1	114	116	PF00400	0.391
TRG_ER_diArg_1	186	189	PF00400	0.363
TRG_ER_diArg_1	191	194	PF00400	0.378
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.455

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P801	Leptomonas seymouri	49%	97%
A4HK64	Leishmania braziliensis	68%	100%
A4I7P9	Leishmania infantum	99%	100%
E9B2K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4Q5J9	Leishmania major	87%	100%