Pentapeptide_repeats_(9_copies)_putative/Pfam:PF1 3599

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Pentapeptide repeats (9 copies), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IKT7_LEIDO

TriTrypDb:

LdBPK_362820.1 , LdCL_360034600 , LDHU3_36.3920

Length:

323

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 8
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IKT7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IKT7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	147	149	PF00675	0.602
CLV_NRD_NRD_1	198	200	PF00675	0.515
CLV_NRD_NRD_1	224	226	PF00675	0.478
CLV_NRD_NRD_1	279	281	PF00675	0.384
CLV_NRD_NRD_1	291	293	PF00675	0.502
CLV_NRD_NRD_1	34	36	PF00675	0.595
CLV_NRD_NRD_1	42	44	PF00675	0.465
CLV_PCSK_FUR_1	145	149	PF00082	0.553
CLV_PCSK_FUR_1	277	281	PF00082	0.365
CLV_PCSK_KEX2_1	147	149	PF00082	0.588
CLV_PCSK_KEX2_1	224	226	PF00082	0.478
CLV_PCSK_KEX2_1	279	281	PF00082	0.384
CLV_PCSK_KEX2_1	34	36	PF00082	0.595
CLV_PCSK_KEX2_1	42	44	PF00082	0.465
CLV_PCSK_SKI1_1	2	6	PF00082	0.458
CLV_PCSK_SKI1_1	97	101	PF00082	0.590
DEG_Nend_UBRbox_1	1	4	PF02207	0.468
DEG_SPOP_SBC_1	65	69	PF00917	0.552
DEG_SPOP_SBC_1	85	89	PF00917	0.573
DOC_CKS1_1	80	85	PF01111	0.534
DOC_CYCLIN_RxL_1	94	102	PF00134	0.541
DOC_PP1_RVXF_1	277	284	PF00149	0.408
DOC_USP7_MATH_1	115	119	PF00917	0.709
DOC_USP7_MATH_1	125	129	PF00917	0.729
DOC_USP7_MATH_1	287	291	PF00917	0.659
DOC_USP7_MATH_1	311	315	PF00917	0.681
DOC_USP7_MATH_1	38	42	PF00917	0.492
DOC_USP7_MATH_1	65	69	PF00917	0.581
DOC_USP7_MATH_2	310	316	PF00917	0.623
DOC_WW_Pin1_4	131	136	PF00397	0.659
DOC_WW_Pin1_4	79	84	PF00397	0.624
LIG_14-3-3_CanoR_1	168	174	PF00244	0.403
LIG_14-3-3_CanoR_1	2	11	PF00244	0.461
LIG_14-3-3_CanoR_1	225	233	PF00244	0.251
LIG_14-3-3_CanoR_1	260	264	PF00244	0.499
LIG_Actin_WH2_2	45	62	PF00022	0.588
LIG_APCC_ABBAyCdc20_2	293	299	PF00400	0.416
LIG_BIR_III_4	242	246	PF00653	0.332
LIG_BRCT_BRCA1_1	209	213	PF00533	0.249
LIG_deltaCOP1_diTrp_1	240	248	PF00928	0.292
LIG_FHA_1	190	196	PF00498	0.267
LIG_FHA_1	265	271	PF00498	0.460
LIG_FHA_1	3	9	PF00498	0.458
LIG_FHA_1	301	307	PF00498	0.561
LIG_FHA_2	111	117	PF00498	0.749
LIG_FHA_2	252	258	PF00498	0.413
LIG_LIR_Apic_2	77	83	PF02991	0.539
LIG_Pex14_2	249	253	PF04695	0.454
LIG_SH2_NCK_1	80	84	PF00017	0.540
LIG_SH2_STAT5	187	190	PF00017	0.332
LIG_SH3_3	109	115	PF00018	0.697
LIG_SH3_3	266	272	PF00018	0.421
LIG_SH3_3	281	287	PF00018	0.577
MOD_CK1_1	127	133	PF00069	0.692
MOD_CK1_1	134	140	PF00069	0.749
MOD_CK1_1	176	182	PF00069	0.272
MOD_CK1_1	219	225	PF00069	0.270
MOD_CK1_1	256	262	PF00069	0.348
MOD_CK1_1	304	310	PF00069	0.443
MOD_CK1_1	72	78	PF00069	0.611
MOD_CK2_1	78	84	PF00069	0.684
MOD_GlcNHglycan	139	142	PF01048	0.645
MOD_GlcNHglycan	163	167	PF01048	0.428
MOD_GlcNHglycan	217	221	PF01048	0.567
MOD_GlcNHglycan	303	306	PF01048	0.582
MOD_GlcNHglycan	71	74	PF01048	0.671
MOD_GlcNHglycan	77	80	PF01048	0.692
MOD_GSK3_1	124	131	PF00069	0.725
MOD_GSK3_1	169	176	PF00069	0.352
MOD_GSK3_1	209	216	PF00069	0.317
MOD_GSK3_1	249	256	PF00069	0.459
MOD_GSK3_1	300	307	PF00069	0.511
MOD_GSK3_1	312	319	PF00069	0.593
MOD_GSK3_1	65	72	PF00069	0.600
MOD_GSK3_1	74	81	PF00069	0.664
MOD_N-GLC_1	173	178	PF02516	0.476
MOD_N-GLC_1	300	305	PF02516	0.702
MOD_N-GLC_2	194	196	PF02516	0.532
MOD_NEK2_1	13	18	PF00069	0.483
MOD_NEK2_1	136	141	PF00069	0.673
MOD_NEK2_1	164	169	PF00069	0.401
MOD_NEK2_1	183	188	PF00069	0.192
MOD_NEK2_1	249	254	PF00069	0.454
MOD_NEK2_1	58	63	PF00069	0.547
MOD_NEK2_1	64	69	PF00069	0.529
MOD_NEK2_2	244	249	PF00069	0.307
MOD_NEK2_2	287	292	PF00069	0.559
MOD_PIKK_1	110	116	PF00454	0.586
MOD_PIKK_1	316	322	PF00454	0.671
MOD_PKA_2	259	265	PF00069	0.432
MOD_PKA_2	59	65	PF00069	0.555
MOD_Plk_1	125	131	PF00069	0.540
MOD_Plk_1	256	262	PF00069	0.337
MOD_Plk_4	183	189	PF00069	0.332
MOD_Plk_4	209	215	PF00069	0.249
MOD_Plk_4	244	250	PF00069	0.249
MOD_Plk_4	265	271	PF00069	0.399
MOD_ProDKin_1	131	137	PF00069	0.659
MOD_ProDKin_1	79	85	PF00069	0.619
TRG_DiLeu_BaEn_1	54	59	PF01217	0.587
TRG_ER_diArg_1	144	147	PF00400	0.629
TRG_ER_diArg_1	277	280	PF00400	0.381
TRG_ER_diArg_1	42	44	PF00400	0.492
TRG_Pf-PMV_PEXEL_1	97	102	PF00026	0.628

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIJ6	Leptomonas seymouri	57%	100%
A0A1X0NM60	Trypanosomatidae	39%	100%
A0A422N6R3	Trypanosoma rangeli	41%	100%
A4ICH5	Leishmania infantum	100%	100%
E9AIX8	Leishmania braziliensis	81%	100%
E9AT46	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q1F2	Leishmania major	91%	100%
V5BPS4	Trypanosoma cruzi	42%	100%