LeishMANIAdb
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Telomerase reverse transcriptase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Telomerase reverse transcriptase
Gene product:
telomerase reverse transcriptase, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IKP2_LEIDO
TriTrypDb:
LdBPK_364120.1 * , LdCL_360048200 , LDHU3_36.5530
Length:
1451

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
Term Name Level Count
GO:0000781 chromosome, telomeric region 3 8
GO:0005634 nucleus 5 8
GO:0043226 organelle 2 8
GO:0043227 membrane-bounded organelle 3 8
GO:0043229 intracellular organelle 3 8
GO:0043231 intracellular membrane-bounded organelle 4 8
GO:0098687 chromosomal region 2 8
GO:0110165 cellular anatomical entity 1 8
GO:0000333 telomerase catalytic core complex 4 1
GO:0005697 telomerase holoenzyme complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0061695 transferase complex, transferring phosphorus-containing groups 4 1
GO:0140513 nuclear protein-containing complex 2 1
GO:1902494 catalytic complex 2 1
GO:1990234 transferase complex 3 1
GO:1990904 ribonucleoprotein complex 2 1

Expansion

Sequence features

A0A3Q8IKP2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0000723 telomere maintenance 5 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006259 DNA metabolic process 4 1
GO:0006278 RNA-templated DNA biosynthetic process 6 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0006996 organelle organization 4 1
GO:0007004 telomere maintenance via telomerase 7 1
GO:0008152 metabolic process 1 1
GO:0009058 biosynthetic process 2 1
GO:0009059 macromolecule biosynthetic process 4 1
GO:0009987 cellular process 1 1
GO:0010833 telomere maintenance via telomere lengthening 6 1
GO:0016043 cellular component organization 3 1
GO:0018130 heterocycle biosynthetic process 4 1
GO:0019438 aromatic compound biosynthetic process 4 1
GO:0032200 telomere organization 6 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0034654 nucleobase-containing compound biosynthetic process 4 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0044271 cellular nitrogen compound biosynthetic process 4 1
GO:0046483 heterocycle metabolic process 3 1
GO:0051276 chromosome organization 5 1
GO:0071704 organic substance metabolic process 2 1
GO:0071840 cellular component organization or biogenesis 2 1
GO:0071897 DNA biosynthetic process 5 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1901362 organic cyclic compound biosynthetic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 8
GO:0003677 DNA binding 4 8
GO:0003721 telomerase RNA reverse transcriptase activity 6 8
GO:0003824 catalytic activity 1 8
GO:0003964 RNA-directed DNA polymerase activity 5 8
GO:0005488 binding 1 8
GO:0016740 transferase activity 2 8
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 8
GO:0016779 nucleotidyltransferase activity 4 8
GO:0034061 DNA polymerase activity 4 8
GO:0043167 ion binding 2 8
GO:0043169 cation binding 3 8
GO:0046872 metal ion binding 4 8
GO:0097159 organic cyclic compound binding 2 8
GO:0140097 catalytic activity, acting on DNA 3 8
GO:0140640 catalytic activity, acting on a nucleic acid 2 8
GO:1901363 heterocyclic compound binding 2 8
GO:0003723 RNA binding 4 1
GO:0042162 telomeric DNA binding 6 1
GO:0043565 sequence-specific DNA binding 5 1
GO:0070034 telomerase RNA binding 5 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 339 343 PF00656 0.479
CLV_C14_Caspase3-7 428 432 PF00656 0.533
CLV_C14_Caspase3-7 802 806 PF00656 0.467
CLV_MEL_PAP_1 1068 1074 PF00089 0.302
CLV_NRD_NRD_1 1112 1114 PF00675 0.387
CLV_NRD_NRD_1 1179 1181 PF00675 0.374
CLV_NRD_NRD_1 1292 1294 PF00675 0.328
CLV_NRD_NRD_1 1367 1369 PF00675 0.515
CLV_NRD_NRD_1 1373 1375 PF00675 0.570
CLV_NRD_NRD_1 1397 1399 PF00675 0.494
CLV_NRD_NRD_1 276 278 PF00675 0.520
CLV_NRD_NRD_1 288 290 PF00675 0.385
CLV_NRD_NRD_1 301 303 PF00675 0.452
CLV_NRD_NRD_1 365 367 PF00675 0.474
CLV_NRD_NRD_1 390 392 PF00675 0.475
CLV_NRD_NRD_1 447 449 PF00675 0.427
CLV_NRD_NRD_1 478 480 PF00675 0.436
CLV_NRD_NRD_1 595 597 PF00675 0.275
CLV_NRD_NRD_1 647 649 PF00675 0.269
CLV_NRD_NRD_1 651 653 PF00675 0.256
CLV_NRD_NRD_1 655 657 PF00675 0.414
CLV_NRD_NRD_1 758 760 PF00675 0.472
CLV_NRD_NRD_1 817 819 PF00675 0.497
CLV_NRD_NRD_1 892 894 PF00675 0.370
CLV_NRD_NRD_1 981 983 PF00675 0.411
CLV_PCSK_FUR_1 1371 1375 PF00082 0.404
CLV_PCSK_FUR_1 299 303 PF00082 0.444
CLV_PCSK_KEX2_1 1112 1114 PF00082 0.367
CLV_PCSK_KEX2_1 1179 1181 PF00082 0.374
CLV_PCSK_KEX2_1 1366 1368 PF00082 0.527
CLV_PCSK_KEX2_1 1373 1375 PF00082 0.574
CLV_PCSK_KEX2_1 1397 1399 PF00082 0.494
CLV_PCSK_KEX2_1 258 260 PF00082 0.500
CLV_PCSK_KEX2_1 276 278 PF00082 0.315
CLV_PCSK_KEX2_1 288 290 PF00082 0.413
CLV_PCSK_KEX2_1 301 303 PF00082 0.570
CLV_PCSK_KEX2_1 365 367 PF00082 0.474
CLV_PCSK_KEX2_1 381 383 PF00082 0.306
CLV_PCSK_KEX2_1 390 392 PF00082 0.407
CLV_PCSK_KEX2_1 447 449 PF00082 0.427
CLV_PCSK_KEX2_1 478 480 PF00082 0.459
CLV_PCSK_KEX2_1 595 597 PF00082 0.249
CLV_PCSK_KEX2_1 647 649 PF00082 0.269
CLV_PCSK_KEX2_1 651 653 PF00082 0.256
CLV_PCSK_KEX2_1 655 657 PF00082 0.414
CLV_PCSK_KEX2_1 758 760 PF00082 0.440
CLV_PCSK_KEX2_1 817 819 PF00082 0.579
CLV_PCSK_KEX2_1 891 893 PF00082 0.356
CLV_PCSK_KEX2_1 981 983 PF00082 0.405
CLV_PCSK_PC1ET2_1 258 260 PF00082 0.500
CLV_PCSK_PC1ET2_1 381 383 PF00082 0.471
CLV_PCSK_PC7_1 647 653 PF00082 0.274
CLV_PCSK_SKI1_1 1048 1052 PF00082 0.359
CLV_PCSK_SKI1_1 1107 1111 PF00082 0.409
CLV_PCSK_SKI1_1 1246 1250 PF00082 0.375
CLV_PCSK_SKI1_1 1329 1333 PF00082 0.523
CLV_PCSK_SKI1_1 172 176 PF00082 0.400
CLV_PCSK_SKI1_1 18 22 PF00082 0.322
CLV_PCSK_SKI1_1 255 259 PF00082 0.532
CLV_PCSK_SKI1_1 447 451 PF00082 0.421
CLV_PCSK_SKI1_1 504 508 PF00082 0.306
CLV_PCSK_SKI1_1 516 520 PF00082 0.306
CLV_PCSK_SKI1_1 637 641 PF00082 0.283
CLV_PCSK_SKI1_1 681 685 PF00082 0.415
CLV_PCSK_SKI1_1 773 777 PF00082 0.527
CLV_PCSK_SKI1_1 845 849 PF00082 0.450
CLV_PCSK_SKI1_1 893 897 PF00082 0.420
CLV_PCSK_SKI1_1 982 986 PF00082 0.406
DEG_APCC_DBOX_1 1055 1063 PF00400 0.427
DEG_APCC_DBOX_1 1245 1253 PF00400 0.379
DEG_APCC_DBOX_1 1396 1404 PF00400 0.522
DEG_APCC_DBOX_1 329 337 PF00400 0.498
DEG_APCC_DBOX_1 446 454 PF00400 0.419
DEG_APCC_DBOX_1 503 511 PF00400 0.506
DEG_APCC_DBOX_1 603 611 PF00400 0.444
DEG_APCC_DBOX_1 757 765 PF00400 0.459
DEG_APCC_DBOX_1 848 856 PF00400 0.413
DEG_APCC_DBOX_1 864 872 PF00400 0.453
DEG_SPOP_SBC_1 1119 1123 PF00917 0.399
DEG_SPOP_SBC_1 585 589 PF00917 0.490
DOC_CKS1_1 434 439 PF01111 0.554
DOC_CKS1_1 492 497 PF01111 0.428
DOC_CKS1_1 699 704 PF01111 0.434
DOC_CKS1_1 93 98 PF01111 0.562
DOC_CYCLIN_RxL_1 1045 1053 PF00134 0.398
DOC_CYCLIN_RxL_1 1104 1115 PF00134 0.416
DOC_CYCLIN_RxL_1 444 452 PF00134 0.384
DOC_CYCLIN_RxL_1 501 509 PF00134 0.506
DOC_CYCLIN_RxL_1 953 963 PF00134 0.400
DOC_CYCLIN_yCln2_LP_2 110 116 PF00134 0.513
DOC_CYCLIN_yCln2_LP_2 1268 1274 PF00134 0.364
DOC_CYCLIN_yCln2_LP_2 179 185 PF00134 0.422
DOC_CYCLIN_yCln2_LP_2 352 358 PF00134 0.500
DOC_CYCLIN_yCln2_LP_2 492 498 PF00134 0.409
DOC_CYCLIN_yCln2_LP_2 639 645 PF00134 0.489
DOC_MAPK_DCC_7 758 766 PF00069 0.464
DOC_MAPK_gen_1 1112 1119 PF00069 0.376
DOC_MAPK_gen_1 1179 1185 PF00069 0.356
DOC_MAPK_gen_1 1260 1269 PF00069 0.394
DOC_MAPK_gen_1 1371 1381 PF00069 0.389
DOC_MAPK_gen_1 330 338 PF00069 0.493
DOC_MAPK_gen_1 758 766 PF00069 0.500
DOC_MAPK_HePTP_8 1206 1218 PF00069 0.339
DOC_MAPK_MEF2A_6 1209 1218 PF00069 0.369
DOC_MAPK_MEF2A_6 1260 1268 PF00069 0.395
DOC_MAPK_MEF2A_6 491 500 PF00069 0.410
DOC_PP1_RVXF_1 635 642 PF00149 0.483
DOC_PP1_RVXF_1 956 963 PF00149 0.399
DOC_PP2B_LxvP_1 352 355 PF13499 0.508
DOC_PP2B_LxvP_1 423 426 PF13499 0.548
DOC_PP4_FxxP_1 11 14 PF00568 0.401
DOC_PP4_FxxP_1 306 309 PF00568 0.484
DOC_PP4_FxxP_1 440 443 PF00568 0.492
DOC_PP4_FxxP_1 834 837 PF00568 0.602
DOC_USP7_MATH_1 1025 1029 PF00917 0.558
DOC_USP7_MATH_1 1105 1109 PF00917 0.366
DOC_USP7_MATH_1 1155 1159 PF00917 0.340
DOC_USP7_MATH_1 1292 1296 PF00917 0.413
DOC_USP7_MATH_1 137 141 PF00917 0.659
DOC_USP7_MATH_1 1413 1417 PF00917 0.583
DOC_USP7_MATH_1 1423 1427 PF00917 0.469
DOC_USP7_MATH_1 246 250 PF00917 0.517
DOC_USP7_MATH_1 528 532 PF00917 0.541
DOC_USP7_MATH_1 585 589 PF00917 0.506
DOC_USP7_MATH_1 64 68 PF00917 0.479
DOC_USP7_MATH_1 670 674 PF00917 0.483
DOC_USP7_MATH_1 683 687 PF00917 0.357
DOC_USP7_MATH_1 906 910 PF00917 0.600
DOC_USP7_MATH_1 947 951 PF00917 0.445
DOC_USP7_UBL2_3 633 637 PF12436 0.483
DOC_WW_Pin1_4 1075 1080 PF00397 0.388
DOC_WW_Pin1_4 1120 1125 PF00397 0.442
DOC_WW_Pin1_4 129 134 PF00397 0.475
DOC_WW_Pin1_4 1335 1340 PF00397 0.531
DOC_WW_Pin1_4 1419 1424 PF00397 0.541
DOC_WW_Pin1_4 305 310 PF00397 0.557
DOC_WW_Pin1_4 34 39 PF00397 0.508
DOC_WW_Pin1_4 430 435 PF00397 0.599
DOC_WW_Pin1_4 491 496 PF00397 0.438
DOC_WW_Pin1_4 575 580 PF00397 0.497
DOC_WW_Pin1_4 698 703 PF00397 0.458
DOC_WW_Pin1_4 779 784 PF00397 0.570
DOC_WW_Pin1_4 78 83 PF00397 0.518
DOC_WW_Pin1_4 87 92 PF00397 0.704
DOC_WW_Pin1_4 909 914 PF00397 0.402
LIG_14-3-3_CanoR_1 1232 1238 PF00244 0.367
LIG_14-3-3_CanoR_1 1293 1299 PF00244 0.452
LIG_14-3-3_CanoR_1 1340 1345 PF00244 0.707
LIG_14-3-3_CanoR_1 1373 1381 PF00244 0.350
LIG_14-3-3_CanoR_1 1397 1401 PF00244 0.469
LIG_14-3-3_CanoR_1 1414 1419 PF00244 0.469
LIG_14-3-3_CanoR_1 1441 1448 PF00244 0.562
LIG_14-3-3_CanoR_1 158 166 PF00244 0.508
LIG_14-3-3_CanoR_1 172 179 PF00244 0.381
LIG_14-3-3_CanoR_1 332 337 PF00244 0.516
LIG_14-3-3_CanoR_1 366 372 PF00244 0.445
LIG_14-3-3_CanoR_1 390 395 PF00244 0.493
LIG_14-3-3_CanoR_1 448 454 PF00244 0.397
LIG_14-3-3_CanoR_1 491 495 PF00244 0.508
LIG_14-3-3_CanoR_1 504 514 PF00244 0.443
LIG_14-3-3_CanoR_1 623 627 PF00244 0.463
LIG_14-3-3_CanoR_1 655 663 PF00244 0.498
LIG_14-3-3_CanoR_1 735 739 PF00244 0.563
LIG_14-3-3_CanoR_1 768 773 PF00244 0.495
LIG_14-3-3_CanoR_1 798 808 PF00244 0.465
LIG_14-3-3_CanoR_1 961 968 PF00244 0.474
LIG_14-3-3_CanoR_1 981 989 PF00244 0.445
LIG_14-3-3_CterR_2 1447 1451 PF00244 0.553
LIG_Actin_WH2_2 209 226 PF00022 0.470
LIG_Actin_WH2_2 496 513 PF00022 0.376
LIG_Actin_WH2_2 610 625 PF00022 0.483
LIG_Actin_WH2_2 945 963 PF00022 0.385
LIG_AP2alpha_2 304 306 PF02296 0.522
LIG_APCC_ABBAyCdc20_2 1004 1010 PF00400 0.455
LIG_BIR_II_1 1 5 PF00653 0.359
LIG_BIR_III_2 431 435 PF00653 0.590
LIG_BIR_III_4 527 531 PF00653 0.483
LIG_BRCT_BRCA1_1 1 5 PF00533 0.418
LIG_BRCT_BRCA1_1 158 162 PF00533 0.319
LIG_BRCT_BRCA1_1 579 583 PF00533 0.474
LIG_BRCT_BRCA1_1 750 754 PF00533 0.571
LIG_DLG_GKlike_1 768 775 PF00625 0.472
LIG_FHA_1 1022 1028 PF00498 0.516
LIG_FHA_1 1169 1175 PF00498 0.388
LIG_FHA_1 1229 1235 PF00498 0.411
LIG_FHA_1 1325 1331 PF00498 0.490
LIG_FHA_1 173 179 PF00498 0.405
LIG_FHA_1 28 34 PF00498 0.427
LIG_FHA_1 468 474 PF00498 0.446
LIG_FHA_1 576 582 PF00498 0.466
LIG_FHA_1 612 618 PF00498 0.506
LIG_FHA_1 633 639 PF00498 0.506
LIG_FHA_1 694 700 PF00498 0.488
LIG_FHA_1 723 729 PF00498 0.368
LIG_FHA_1 810 816 PF00498 0.538
LIG_FHA_1 902 908 PF00498 0.551
LIG_FHA_1 984 990 PF00498 0.443
LIG_FHA_2 1168 1174 PF00498 0.371
LIG_FHA_2 120 126 PF00498 0.473
LIG_FHA_2 1234 1240 PF00498 0.323
LIG_FHA_2 322 328 PF00498 0.454
LIG_FHA_2 402 408 PF00498 0.479
LIG_FHA_2 450 456 PF00498 0.459
LIG_FHA_2 492 498 PF00498 0.390
LIG_GBD_Chelix_1 1080 1088 PF00786 0.322
LIG_GBD_Chelix_1 499 507 PF00786 0.306
LIG_Integrin_RGD_1 1198 1200 PF01839 0.455
LIG_LIR_Apic_2 303 309 PF02991 0.483
LIG_LIR_Gen_1 1086 1097 PF02991 0.402
LIG_LIR_Gen_1 1207 1218 PF02991 0.371
LIG_LIR_Gen_1 67 76 PF02991 0.370
LIG_LIR_Gen_1 746 756 PF02991 0.354
LIG_LIR_Gen_1 878 886 PF02991 0.398
LIG_LIR_Gen_1 933 944 PF02991 0.452
LIG_LIR_LC3C_4 67 71 PF02991 0.410
LIG_LIR_Nem_3 105 110 PF02991 0.446
LIG_LIR_Nem_3 1086 1092 PF02991 0.394
LIG_LIR_Nem_3 1175 1181 PF02991 0.382
LIG_LIR_Nem_3 1207 1213 PF02991 0.371
LIG_LIR_Nem_3 1236 1240 PF02991 0.397
LIG_LIR_Nem_3 1383 1387 PF02991 0.343
LIG_LIR_Nem_3 159 165 PF02991 0.434
LIG_LIR_Nem_3 2 8 PF02991 0.423
LIG_LIR_Nem_3 200 205 PF02991 0.370
LIG_LIR_Nem_3 22 27 PF02991 0.192
LIG_LIR_Nem_3 267 272 PF02991 0.384
LIG_LIR_Nem_3 509 515 PF02991 0.494
LIG_LIR_Nem_3 67 71 PF02991 0.334
LIG_LIR_Nem_3 718 723 PF02991 0.482
LIG_LIR_Nem_3 746 752 PF02991 0.479
LIG_LIR_Nem_3 878 883 PF02991 0.395
LIG_LIR_Nem_3 933 939 PF02991 0.447
LIG_LIR_Nem_3 955 960 PF02991 0.332
LIG_MYND_1 1419 1423 PF01753 0.469
LIG_NRBOX 1278 1284 PF00104 0.373
LIG_NRBOX 445 451 PF00104 0.381
LIG_NRBOX 502 508 PF00104 0.506
LIG_PAM2_1 912 924 PF00658 0.292
LIG_PCNA_TLS_4 18 25 PF02747 0.380
LIG_Pex14_1 183 187 PF04695 0.345
LIG_Pex14_1 570 574 PF04695 0.463
LIG_Pex14_2 626 630 PF04695 0.506
LIG_Pex14_2 640 644 PF04695 0.506
LIG_SH2_CRK 202 206 PF00017 0.391
LIG_SH2_CRK 749 753 PF00017 0.483
LIG_SH2_CRK 936 940 PF00017 0.440
LIG_SH2_CRK 957 961 PF00017 0.398
LIG_SH2_GRB2like 166 169 PF00017 0.418
LIG_SH2_GRB2like 936 939 PF00017 0.443
LIG_SH2_NCK_1 786 790 PF00017 0.445
LIG_SH2_PTP2 73 76 PF00017 0.461
LIG_SH2_PTP2 924 927 PF00017 0.347
LIG_SH2_STAP1 334 338 PF00017 0.573
LIG_SH2_STAT3 1205 1208 PF00017 0.394
LIG_SH2_STAT5 1143 1146 PF00017 0.449
LIG_SH2_STAT5 1195 1198 PF00017 0.483
LIG_SH2_STAT5 1205 1208 PF00017 0.488
LIG_SH2_STAT5 127 130 PF00017 0.407
LIG_SH2_STAT5 1363 1366 PF00017 0.373
LIG_SH2_STAT5 166 169 PF00017 0.426
LIG_SH2_STAT5 202 205 PF00017 0.391
LIG_SH2_STAT5 24 27 PF00017 0.381
LIG_SH2_STAT5 251 254 PF00017 0.457
LIG_SH2_STAT5 445 448 PF00017 0.395
LIG_SH2_STAT5 472 475 PF00017 0.468
LIG_SH2_STAT5 502 505 PF00017 0.463
LIG_SH2_STAT5 575 578 PF00017 0.506
LIG_SH2_STAT5 73 76 PF00017 0.385
LIG_SH2_STAT5 924 927 PF00017 0.347
LIG_SH3_1 891 897 PF00018 0.349
LIG_SH3_2 434 439 PF14604 0.554
LIG_SH3_2 840 845 PF14604 0.490
LIG_SH3_3 1187 1193 PF00018 0.413
LIG_SH3_3 215 221 PF00018 0.411
LIG_SH3_3 3 9 PF00018 0.343
LIG_SH3_3 419 425 PF00018 0.445
LIG_SH3_3 431 437 PF00018 0.482
LIG_SH3_3 57 63 PF00018 0.397
LIG_SH3_3 576 582 PF00018 0.483
LIG_SH3_3 834 840 PF00018 0.582
LIG_SH3_3 88 94 PF00018 0.644
LIG_SH3_3 891 897 PF00018 0.354
LIG_SUMO_SIM_anti_2 493 501 PF11976 0.367
LIG_SUMO_SIM_anti_2 67 73 PF11976 0.382
LIG_SUMO_SIM_par_1 1058 1063 PF11976 0.433
LIG_SUMO_SIM_par_1 1169 1175 PF11976 0.376
LIG_TYR_ITIM 71 76 PF00017 0.455
LIG_WRC_WIRS_1 1234 1239 PF05994 0.384
LIG_WRC_WIRS_1 1381 1386 PF05994 0.394
LIG_WRC_WIRS_1 883 888 PF05994 0.400
MOD_CDK_SPK_2 1335 1340 PF00069 0.531
MOD_CDK_SPK_2 36 41 PF00069 0.483
MOD_CDK_SPxK_1 433 439 PF00069 0.561
MOD_CDK_SPxxK_3 129 136 PF00069 0.395
MOD_CDK_SPxxK_3 305 312 PF00069 0.517
MOD_CDK_SPxxK_3 34 41 PF00069 0.471
MOD_CK1_1 1028 1034 PF00069 0.615
MOD_CK1_1 1145 1151 PF00069 0.409
MOD_CK1_1 139 145 PF00069 0.720
MOD_CK1_1 4 10 PF00069 0.422
MOD_CK1_1 433 439 PF00069 0.545
MOD_CK1_1 584 590 PF00069 0.299
MOD_CK1_1 632 638 PF00069 0.360
MOD_CK1_1 673 679 PF00069 0.423
MOD_CK1_1 704 710 PF00069 0.405
MOD_CK1_1 771 777 PF00069 0.513
MOD_CK1_1 784 790 PF00069 0.512
MOD_CK1_1 872 878 PF00069 0.493
MOD_CK1_1 909 915 PF00069 0.402
MOD_CK1_1 930 936 PF00069 0.448
MOD_CK2_1 1167 1173 PF00069 0.371
MOD_CK2_1 1233 1239 PF00069 0.325
MOD_CK2_1 1297 1303 PF00069 0.384
MOD_CK2_1 401 407 PF00069 0.478
MOD_CK2_1 771 777 PF00069 0.535
MOD_CK2_1 854 860 PF00069 0.463
MOD_CK2_1 882 888 PF00069 0.460
MOD_Cter_Amidation 286 289 PF01082 0.496
MOD_GlcNHglycan 1 4 PF01048 0.392
MOD_GlcNHglycan 1018 1021 PF01048 0.577
MOD_GlcNHglycan 102 105 PF01048 0.594
MOD_GlcNHglycan 1042 1045 PF01048 0.344
MOD_GlcNHglycan 1062 1065 PF01048 0.228
MOD_GlcNHglycan 1097 1100 PF01048 0.483
MOD_GlcNHglycan 1294 1297 PF01048 0.364
MOD_GlcNHglycan 1298 1302 PF01048 0.325
MOD_GlcNHglycan 1357 1360 PF01048 0.476
MOD_GlcNHglycan 1423 1426 PF01048 0.504
MOD_GlcNHglycan 1443 1446 PF01048 0.506
MOD_GlcNHglycan 159 162 PF01048 0.415
MOD_GlcNHglycan 232 235 PF01048 0.557
MOD_GlcNHglycan 248 251 PF01048 0.560
MOD_GlcNHglycan 265 269 PF01048 0.320
MOD_GlcNHglycan 346 350 PF01048 0.496
MOD_GlcNHglycan 387 390 PF01048 0.454
MOD_GlcNHglycan 427 430 PF01048 0.546
MOD_GlcNHglycan 49 52 PF01048 0.505
MOD_GlcNHglycan 583 586 PF01048 0.375
MOD_GlcNHglycan 588 591 PF01048 0.346
MOD_GlcNHglycan 672 675 PF01048 0.482
MOD_GlcNHglycan 685 688 PF01048 0.376
MOD_GlcNHglycan 703 706 PF01048 0.338
MOD_GlcNHglycan 709 712 PF01048 0.469
MOD_GlcNHglycan 713 716 PF01048 0.554
MOD_GlcNHglycan 768 771 PF01048 0.513
MOD_GlcNHglycan 789 792 PF01048 0.407
MOD_GlcNHglycan 856 859 PF01048 0.538
MOD_GlcNHglycan 909 912 PF01048 0.506
MOD_GlcNHglycan 914 917 PF01048 0.444
MOD_GSK3_1 1016 1023 PF00069 0.657
MOD_GSK3_1 1027 1034 PF00069 0.512
MOD_GSK3_1 1095 1102 PF00069 0.360
MOD_GSK3_1 115 122 PF00069 0.525
MOD_GSK3_1 1151 1158 PF00069 0.409
MOD_GSK3_1 1168 1175 PF00069 0.345
MOD_GSK3_1 1335 1342 PF00069 0.544
MOD_GSK3_1 1350 1357 PF00069 0.371
MOD_GSK3_1 136 143 PF00069 0.546
MOD_GSK3_1 1413 1420 PF00069 0.636
MOD_GSK3_1 1421 1428 PF00069 0.556
MOD_GSK3_1 228 235 PF00069 0.429
MOD_GSK3_1 246 253 PF00069 0.559
MOD_GSK3_1 260 267 PF00069 0.349
MOD_GSK3_1 32 39 PF00069 0.494
MOD_GSK3_1 328 335 PF00069 0.463
MOD_GSK3_1 390 397 PF00069 0.406
MOD_GSK3_1 398 405 PF00069 0.384
MOD_GSK3_1 498 505 PF00069 0.309
MOD_GSK3_1 573 580 PF00069 0.360
MOD_GSK3_1 581 588 PF00069 0.360
MOD_GSK3_1 622 629 PF00069 0.390
MOD_GSK3_1 707 714 PF00069 0.477
MOD_GSK3_1 78 85 PF00069 0.560
MOD_GSK3_1 923 930 PF00069 0.391
MOD_LATS_1 1439 1445 PF00433 0.560
MOD_N-GLC_1 1031 1036 PF02516 0.337
MOD_N-GLC_1 137 142 PF02516 0.513
MOD_N-GLC_1 167 172 PF02516 0.423
MOD_N-GLC_1 519 524 PF02516 0.304
MOD_N-GLC_1 64 69 PF02516 0.396
MOD_N-GLC_1 872 877 PF02516 0.519
MOD_N-GLC_2 1261 1263 PF02516 0.352
MOD_NEK2_1 1 6 PF00069 0.419
MOD_NEK2_1 1118 1123 PF00069 0.363
MOD_NEK2_1 1150 1155 PF00069 0.395
MOD_NEK2_1 1167 1172 PF00069 0.371
MOD_NEK2_1 1184 1189 PF00069 0.378
MOD_NEK2_1 1204 1209 PF00069 0.191
MOD_NEK2_1 1242 1247 PF00069 0.308
MOD_NEK2_1 1312 1317 PF00069 0.352
MOD_NEK2_1 1443 1448 PF00069 0.562
MOD_NEK2_1 156 161 PF00069 0.427
MOD_NEK2_1 164 169 PF00069 0.377
MOD_NEK2_1 228 233 PF00069 0.654
MOD_NEK2_1 27 32 PF00069 0.364
MOD_NEK2_1 449 454 PF00069 0.368
MOD_NEK2_1 467 472 PF00069 0.310
MOD_NEK2_1 506 511 PF00069 0.360
MOD_NEK2_1 574 579 PF00069 0.328
MOD_NEK2_1 622 627 PF00069 0.360
MOD_NEK2_1 748 753 PF00069 0.502
MOD_NEK2_1 76 81 PF00069 0.484
MOD_NEK2_1 960 965 PF00069 0.381
MOD_NEK2_1 980 985 PF00069 0.341
MOD_PIKK_1 1204 1210 PF00454 0.379
MOD_PIKK_1 611 617 PF00454 0.454
MOD_PIKK_1 662 668 PF00454 0.637
MOD_PK_1 332 338 PF00069 0.517
MOD_PK_1 390 396 PF00069 0.478
MOD_PKA_1 1373 1379 PF00069 0.390
MOD_PKA_1 390 396 PF00069 0.478
MOD_PKA_2 1028 1034 PF00069 0.472
MOD_PKA_2 1292 1298 PF00069 0.407
MOD_PKA_2 1339 1345 PF00069 0.633
MOD_PKA_2 1373 1379 PF00069 0.567
MOD_PKA_2 1396 1402 PF00069 0.460
MOD_PKA_2 1413 1419 PF00069 0.469
MOD_PKA_2 157 163 PF00069 0.417
MOD_PKA_2 336 342 PF00069 0.568
MOD_PKA_2 390 396 PF00069 0.493
MOD_PKA_2 398 404 PF00069 0.472
MOD_PKA_2 490 496 PF00069 0.446
MOD_PKA_2 622 628 PF00069 0.300
MOD_PKA_2 654 660 PF00069 0.527
MOD_PKA_2 734 740 PF00069 0.515
MOD_PKA_2 869 875 PF00069 0.566
MOD_PKA_2 960 966 PF00069 0.373
MOD_PKA_2 980 986 PF00069 0.417
MOD_PKB_1 1371 1379 PF00069 0.363
MOD_PKB_1 330 338 PF00069 0.537
MOD_Plk_1 1105 1111 PF00069 0.482
MOD_Plk_1 1168 1174 PF00069 0.371
MOD_Plk_1 228 234 PF00069 0.662
MOD_Plk_1 519 525 PF00069 0.243
MOD_Plk_1 596 602 PF00069 0.376
MOD_Plk_1 64 70 PF00069 0.399
MOD_Plk_2-3 882 888 PF00069 0.460
MOD_Plk_4 1155 1161 PF00069 0.332
MOD_Plk_4 1218 1224 PF00069 0.449
MOD_Plk_4 123 129 PF00069 0.400
MOD_Plk_4 1233 1239 PF00069 0.357
MOD_Plk_4 1425 1431 PF00069 0.570
MOD_Plk_4 441 447 PF00069 0.483
MOD_Plk_4 449 455 PF00069 0.366
MOD_Plk_4 498 504 PF00069 0.360
MOD_Plk_4 64 70 PF00069 0.399
MOD_Plk_4 811 817 PF00069 0.597
MOD_Plk_4 923 929 PF00069 0.397
MOD_Plk_4 947 953 PF00069 0.439
MOD_ProDKin_1 1075 1081 PF00069 0.387
MOD_ProDKin_1 1120 1126 PF00069 0.444
MOD_ProDKin_1 129 135 PF00069 0.473
MOD_ProDKin_1 1335 1341 PF00069 0.535
MOD_ProDKin_1 1419 1425 PF00069 0.538
MOD_ProDKin_1 305 311 PF00069 0.551
MOD_ProDKin_1 34 40 PF00069 0.515
MOD_ProDKin_1 430 436 PF00069 0.597
MOD_ProDKin_1 491 497 PF00069 0.434
MOD_ProDKin_1 575 581 PF00069 0.347
MOD_ProDKin_1 698 704 PF00069 0.458
MOD_ProDKin_1 779 785 PF00069 0.565
MOD_ProDKin_1 78 84 PF00069 0.533
MOD_ProDKin_1 87 93 PF00069 0.699
MOD_ProDKin_1 909 915 PF00069 0.394
MOD_SUMO_rev_2 238 244 PF00179 0.625
TRG_DiLeu_BaEn_1 1106 1111 PF01217 0.352
TRG_DiLeu_BaEn_2 264 270 PF01217 0.383
TRG_DiLeu_BaEn_4 1013 1019 PF01217 0.419
TRG_DiLeu_BaEn_4 22 28 PF01217 0.352
TRG_DiLeu_BaLyEn_6 1278 1283 PF01217 0.373
TRG_DiLeu_BaLyEn_6 445 450 PF01217 0.384
TRG_DiLeu_BaLyEn_6 645 650 PF01217 0.243
TRG_DiLeu_BaLyEn_6 791 796 PF01217 0.425
TRG_ENDOCYTIC_2 202 205 PF00928 0.391
TRG_ENDOCYTIC_2 24 27 PF00928 0.381
TRG_ENDOCYTIC_2 73 76 PF00928 0.461
TRG_ENDOCYTIC_2 749 752 PF00928 0.427
TRG_ENDOCYTIC_2 880 883 PF00928 0.397
TRG_ENDOCYTIC_2 924 927 PF00928 0.385
TRG_ENDOCYTIC_2 936 939 PF00928 0.339
TRG_ENDOCYTIC_2 957 960 PF00928 0.337
TRG_ER_diArg_1 1111 1113 PF00400 0.362
TRG_ER_diArg_1 1178 1180 PF00400 0.344
TRG_ER_diArg_1 1347 1350 PF00400 0.460
TRG_ER_diArg_1 1366 1368 PF00400 0.488
TRG_ER_diArg_1 1371 1374 PF00400 0.409
TRG_ER_diArg_1 1396 1398 PF00400 0.429
TRG_ER_diArg_1 276 278 PF00400 0.520
TRG_ER_diArg_1 288 290 PF00400 0.385
TRG_ER_diArg_1 299 302 PF00400 0.461
TRG_ER_diArg_1 329 332 PF00400 0.478
TRG_ER_diArg_1 364 366 PF00400 0.474
TRG_ER_diArg_1 390 392 PF00400 0.427
TRG_ER_diArg_1 446 448 PF00400 0.437
TRG_ER_diArg_1 477 479 PF00400 0.439
TRG_ER_diArg_1 646 648 PF00400 0.319
TRG_ER_diArg_1 650 652 PF00400 0.300
TRG_ER_diArg_1 654 656 PF00400 0.278
TRG_ER_diArg_1 816 818 PF00400 0.494
TRG_ER_diArg_1 890 893 PF00400 0.409
TRG_ER_diArg_1 980 982 PF00400 0.413
TRG_NLS_MonoExtC_3 758 763 PF00514 0.489
TRG_NLS_MonoExtN_4 1366 1372 PF00514 0.402
TRG_NLS_MonoExtN_4 756 763 PF00514 0.480
TRG_Pf-PMV_PEXEL_1 1048 1053 PF00026 0.417
TRG_Pf-PMV_PEXEL_1 172 176 PF00026 0.404
TRG_Pf-PMV_PEXEL_1 419 424 PF00026 0.438
TRG_Pf-PMV_PEXEL_1 55 59 PF00026 0.514
TRG_Pf-PMV_PEXEL_1 773 777 PF00026 0.544

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HXN9 Leptomonas seymouri 49% 100%
A4HPR1 Leishmania braziliensis 78% 100%
A4ID03 Leishmania infantum 100% 100%
D0A8M4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
E9ATH5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 99%
Q4Q122 Leishmania major 90% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS