LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3Q8IKG3_LEIDO
TriTrypDb:
LdBPK_200520.1 , LdCL_200009900 , LDHU3_20.0620
Length:
96

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IKG3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IKG3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 13 15 PF00675 0.568
CLV_NRD_NRD_1 81 83 PF00675 0.629
CLV_PCSK_KEX2_1 12 14 PF00082 0.574
CLV_PCSK_KEX2_1 81 83 PF00082 0.559
DEG_Nend_UBRbox_3 1 3 PF02207 0.540
DEG_SCF_FBW7_1 60 67 PF00400 0.476
DOC_CKS1_1 61 66 PF01111 0.475
DOC_USP7_MATH_1 64 68 PF00917 0.534
DOC_USP7_UBL2_3 89 93 PF12436 0.579
DOC_WW_Pin1_4 60 65 PF00397 0.474
DOC_WW_Pin1_4 73 78 PF00397 0.424
LIG_14-3-3_CanoR_1 52 61 PF00244 0.494
LIG_Actin_WH2_2 66 83 PF00022 0.474
LIG_FHA_1 54 60 PF00498 0.502
LIG_FHA_1 61 67 PF00498 0.457
LIG_FHA_2 29 35 PF00498 0.531
LIG_FHA_2 86 92 PF00498 0.568
LIG_LIR_Gen_1 56 66 PF02991 0.450
LIG_LIR_Nem_3 56 61 PF02991 0.456
LIG_SH2_STAT5 45 48 PF00017 0.461
LIG_SH3_2 18 23 PF14604 0.573
LIG_SH3_3 15 21 PF00018 0.559
LIG_SH3_3 58 64 PF00018 0.448
LIG_WRC_WIRS_1 65 70 PF05994 0.467
MOD_CK2_1 85 91 PF00069 0.567
MOD_GlcNHglycan 82 85 PF01048 0.577
MOD_GSK3_1 60 67 PF00069 0.566
MOD_GSK3_1 69 76 PF00069 0.493
MOD_NEK2_1 80 85 PF00069 0.576
MOD_PIKK_1 38 44 PF00454 0.538
MOD_PKA_2 80 86 PF00069 0.577
MOD_Plk_4 64 70 PF00069 0.465
MOD_ProDKin_1 60 66 PF00069 0.473
MOD_ProDKin_1 73 79 PF00069 0.429
MOD_SUMO_rev_2 29 37 PF00179 0.548
TRG_ER_diArg_1 12 14 PF00400 0.576
TRG_ER_diArg_1 49 52 PF00400 0.514
TRG_ER_diArg_1 80 82 PF00400 0.557

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HW26 Leptomonas seymouri 47% 100%
A4HYR6 Leishmania infantum 100% 100%
E9AUI9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 73% 71%
Q4QCZ5 Leishmania major 85% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS