Clathrin coat assembly protein-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

clathrin coat assembly protein-like protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IKF7_LEIDO

TriTrypDb:

LdBPK_363180.1 , LdCL_360038400 , LDHU3_36.4390

Length:

438

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0030119	AP-type membrane coat adaptor complex	3	11
GO:0030131	clathrin adaptor complex	4	11
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0032991	protein-containing complex	1	11
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

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Expansion

Sequence features

A0A3Q8IKF7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IKF7

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	11
GO:0006886	intracellular protein transport	4	11
GO:0006897	endocytosis	5	1
GO:0008104	protein localization	4	11
GO:0009987	cellular process	1	11
GO:0015031	protein transport	4	11
GO:0016192	vesicle-mediated transport	4	11
GO:0033036	macromolecule localization	2	11
GO:0045184	establishment of protein localization	3	11
GO:0046907	intracellular transport	3	11

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.539
CLV_NRD_NRD_1	263	265	PF00675	0.307
CLV_PCSK_KEX2_1	100	102	PF00082	0.353
CLV_PCSK_KEX2_1	263	265	PF00082	0.307
CLV_PCSK_KEX2_1	52	54	PF00082	0.330
CLV_PCSK_PC1ET2_1	100	102	PF00082	0.353
CLV_PCSK_PC1ET2_1	52	54	PF00082	0.330
CLV_PCSK_SKI1_1	100	104	PF00082	0.510
CLV_PCSK_SKI1_1	263	267	PF00082	0.419
CLV_PCSK_SKI1_1	318	322	PF00082	0.409

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6F2	Leptomonas seymouri	25%	92%
A0A0N1I7F0	Leptomonas seymouri	29%	100%
A0A0N1ILY9	Leptomonas seymouri	70%	100%
A0A0N1PAY6	Leptomonas seymouri	23%	97%
A0A0S4INT9	Bodo saltans	25%	96%
A0A0S4JHW9	Bodo saltans	42%	95%
A0A0S4JX54	Bodo saltans	23%	90%
A0A1X0NJW3	Trypanosomatidae	27%	97%
A0A1X0NL86	Trypanosomatidae	46%	100%
A0A1X0NTD3	Trypanosomatidae	30%	100%

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