Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IKD2_LEIDO

TriTrypDb:

LdCL_360018400

Length:

117

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A0A3Q8IKD2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IKD2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	70	72	PF00675	0.511
CLV_NRD_NRD_1	86	88	PF00675	0.455
CLV_PCSK_KEX2_1	70	72	PF00082	0.514
CLV_PCSK_KEX2_1	88	90	PF00082	0.422
CLV_PCSK_PC1ET2_1	88	90	PF00082	0.431
DEG_Nend_UBRbox_2	1	3	PF02207	0.672
DOC_CDC14_PxL_1	3	11	PF14671	0.585
DOC_MAPK_FxFP_2	51	54	PF00069	0.280
DOC_MAPK_gen_1	87	96	PF00069	0.627
DOC_PP1_RVXF_1	91	97	PF00149	0.676
DOC_PP2B_LxvP_1	4	7	PF13499	0.587
DOC_PP4_FxxP_1	51	54	PF00568	0.280
DOC_WW_Pin1_4	45	50	PF00397	0.307
LIG_14-3-3_CanoR_1	10	15	PF00244	0.575
LIG_Actin_WH2_2	16	34	PF00022	0.226
LIG_BRCT_BRCA1_1	47	51	PF00533	0.269
LIG_BRCT_BRCA1_1	55	59	PF00533	0.259
LIG_FHA_1	32	38	PF00498	0.447
LIG_LIR_Apic_2	48	54	PF02991	0.278
LIG_LIR_Gen_1	13	22	PF02991	0.524
LIG_LIR_Gen_1	55	63	PF02991	0.279
LIG_LIR_Gen_1	97	105	PF02991	0.674
LIG_LIR_Nem_3	13	17	PF02991	0.535
LIG_LIR_Nem_3	20	25	PF02991	0.284
LIG_LIR_Nem_3	48	53	PF02991	0.512
LIG_LIR_Nem_3	55	60	PF02991	0.420
LIG_LIR_Nem_3	97	103	PF02991	0.671
LIG_MLH1_MIPbox_1	47	51	PF16413	0.226
LIG_Pex14_2	53	57	PF04695	0.343
LIG_SH2_CRK	14	18	PF00017	0.515
LIG_SH2_NCK_1	14	18	PF00017	0.457
LIG_SH2_PTP2	18	21	PF00017	0.361
LIG_SH2_PTP2	22	25	PF00017	0.329
LIG_SH2_PTP2	26	29	PF00017	0.296
LIG_SH2_SRC	18	21	PF00017	0.361
LIG_SH2_SRC	22	25	PF00017	0.329
LIG_SH2_SRC	26	29	PF00017	0.296
LIG_SH2_STAP1	14	18	PF00017	0.457
LIG_SH2_STAT5	100	103	PF00017	0.675
LIG_SH2_STAT5	12	15	PF00017	0.607
LIG_SH2_STAT5	18	21	PF00017	0.329
LIG_SH2_STAT5	22	25	PF00017	0.296
LIG_SH2_STAT5	26	29	PF00017	0.264
LIG_SH2_STAT5	30	33	PF00017	0.232
LIG_SUMO_SIM_par_1	2	8	PF11976	0.590
LIG_TRFH_1	50	54	PF08558	0.226
MOD_CK1_1	5	11	PF00069	0.638
MOD_CK1_1	55	61	PF00069	0.264
MOD_CK1_1	69	75	PF00069	0.629
MOD_GSK3_1	55	62	PF00069	0.226
MOD_GSK3_1	66	73	PF00069	0.624
MOD_GSK3_1	95	102	PF00069	0.752
MOD_N-GLC_1	109	114	PF02516	0.453
MOD_NEK2_1	31	36	PF00069	0.412
MOD_NEK2_1	59	64	PF00069	0.508
MOD_NEK2_1	94	99	PF00069	0.785
MOD_NEK2_2	95	100	PF00069	0.671
MOD_PIKK_1	109	115	PF00454	0.659
MOD_PKA_1	70	76	PF00069	0.686
MOD_PKA_1	89	95	PF00069	0.577
MOD_PKA_2	31	37	PF00069	0.226
MOD_PKA_2	69	75	PF00069	0.700
MOD_PKB_1	87	95	PF00069	0.627
MOD_Plk_4	13	19	PF00069	0.515
MOD_Plk_4	95	101	PF00069	0.671
MOD_ProDKin_1	45	51	PF00069	0.307
TRG_ENDOCYTIC_2	100	103	PF00928	0.675
TRG_ENDOCYTIC_2	14	17	PF00928	0.538
TRG_ENDOCYTIC_2	18	21	PF00928	0.313
TRG_ENDOCYTIC_2	22	25	PF00928	0.280
TRG_ENDOCYTIC_2	26	29	PF00928	0.248
TRG_ENDOCYTIC_2	30	33	PF00928	0.216

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AG14	Leishmania major	53%	100%
E9AHX2	Leishmania infantum	74%	97%