Hypothetical_protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IK43_LEIDO

TriTrypDb:

LdCL_310026600 , LDHU3_31.3350

Length:

231

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8IK43

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IK43

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	206	208	PF00675	0.540
CLV_PCSK_KEX2_1	206	208	PF00082	0.540
DEG_Nend_UBRbox_3	1	3	PF02207	0.308
DOC_CKS1_1	201	206	PF01111	0.657
DOC_PP4_FxxP_1	120	123	PF00568	0.610
DOC_USP7_MATH_1	180	184	PF00917	0.636
DOC_USP7_MATH_1	213	217	PF00917	0.689
DOC_WW_Pin1_4	162	167	PF00397	0.625
DOC_WW_Pin1_4	168	173	PF00397	0.624
DOC_WW_Pin1_4	182	187	PF00397	0.684
DOC_WW_Pin1_4	188	193	PF00397	0.811
DOC_WW_Pin1_4	200	205	PF00397	0.680
LIG_14-3-3_CanoR_1	181	187	PF00244	0.761
LIG_APCC_ABBAyCdc20_2	41	47	PF00400	0.611
LIG_BIR_III_4	144	148	PF00653	0.641
LIG_BIR_III_4	58	62	PF00653	0.632
LIG_EH1_1	9	17	PF00400	0.249
LIG_eIF4E_1	4	10	PF01652	0.205
LIG_FHA_1	11	17	PF00498	0.256
LIG_IRF3_LxIS_1	14	20	PF10401	0.249
LIG_LIR_Apic_2	117	123	PF02991	0.615
LIG_LIR_Gen_1	3	12	PF02991	0.276
LIG_LIR_Gen_1	39	50	PF02991	0.748
LIG_LIR_Nem_3	3	8	PF02991	0.347
LIG_LIR_Nem_3	39	45	PF02991	0.749
LIG_SH2_CRK	201	205	PF00017	0.660
LIG_SH2_SRC	71	74	PF00017	0.642
LIG_SH2_STAT3	75	78	PF00017	0.576
LIG_SH2_STAT5	178	181	PF00017	0.683
LIG_SH2_STAT5	4	7	PF00017	0.282
LIG_SH3_2	60	65	PF14604	0.627
LIG_SH3_3	128	134	PF00018	0.633
LIG_SH3_3	193	199	PF00018	0.671
LIG_SH3_3	57	63	PF00018	0.640
LIG_SUMO_SIM_anti_2	13	18	PF11976	0.233
LIG_TRAF2_1	216	219	PF00917	0.620
LIG_WW_1	198	201	PF00397	0.649
LIG_WW_3	62	66	PF00397	0.584
MOD_CDC14_SPxK_1	191	194	PF00782	0.614
MOD_CDK_SPxK_1	188	194	PF00069	0.616
MOD_CDK_SPxK_1	200	206	PF00069	0.621
MOD_CDK_SPxxK_3	200	207	PF00069	0.622
MOD_CK1_1	149	155	PF00069	0.642
MOD_CK2_1	162	168	PF00069	0.639
MOD_CK2_1	213	219	PF00069	0.623
MOD_DYRK1A_RPxSP_1	162	166	PF00069	0.612
MOD_GlcNHglycan	182	185	PF01048	0.401
MOD_GlcNHglycan	219	223	PF01048	0.417
MOD_GSK3_1	214	221	PF00069	0.659
MOD_N-GLC_1	129	134	PF02516	0.392
MOD_N-GLC_1	149	154	PF02516	0.426
MOD_NEK2_1	10	15	PF00069	0.285
MOD_NEK2_1	17	22	PF00069	0.214
MOD_PIKK_1	107	113	PF00454	0.614
MOD_PIKK_1	214	220	PF00454	0.679
MOD_PKA_2	180	186	PF00069	0.758
MOD_Plk_4	10	16	PF00069	0.271
MOD_Plk_4	114	120	PF00069	0.606
MOD_ProDKin_1	162	168	PF00069	0.624
MOD_ProDKin_1	182	188	PF00069	0.686
MOD_ProDKin_1	200	206	PF00069	0.672
TRG_DiLeu_BaEn_2	2	8	PF01217	0.300
TRG_ENDOCYTIC_2	4	7	PF00928	0.338
TRG_ENDOCYTIC_2	42	45	PF00928	0.657
TRG_ENDOCYTIC_2	71	74	PF00928	0.642
TRG_ER_diArg_1	205	207	PF00400	0.629
TRG_ER_diArg_1	27	30	PF00400	0.534
TRG_ER_diLys_1	226	231	PF00400	0.631

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTR7	Leptomonas seymouri	34%	97%