Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IJW3_LEIDO

TriTrypDb:

LdBPK_310780.1 , LdCL_310013600 , LDHU3_31.1140

Length:

297

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IJW3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IJW3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	193	197	PF00656	0.537
CLV_NRD_NRD_1	62	64	PF00675	0.574
CLV_PCSK_SKI1_1	130	134	PF00082	0.559
CLV_PCSK_SKI1_1	150	154	PF00082	0.331
CLV_PCSK_SKI1_1	190	194	PF00082	0.529
CLV_PCSK_SKI1_1	22	26	PF00082	0.531
CLV_PCSK_SKI1_1	32	36	PF00082	0.507
DEG_APCC_DBOX_1	100	108	PF00400	0.390
DOC_CKS1_1	253	258	PF01111	0.606
DOC_PP2B_LxvP_1	218	221	PF13499	0.542
DOC_PP2B_LxvP_1	233	236	PF13499	0.500
DOC_PP4_MxPP_1	224	227	PF00568	0.656
DOC_USP7_MATH_1	201	205	PF00917	0.477
DOC_USP7_MATH_1	239	243	PF00917	0.669
DOC_USP7_MATH_1	271	275	PF00917	0.597
DOC_USP7_UBL2_3	130	134	PF12436	0.580
DOC_USP7_UBL2_3	146	150	PF12436	0.551
DOC_USP7_UBL2_3	153	157	PF12436	0.467
DOC_WW_Pin1_4	137	142	PF00397	0.504
DOC_WW_Pin1_4	252	257	PF00397	0.725
DOC_WW_Pin1_4	4	9	PF00397	0.464
DOC_WW_Pin1_4	75	80	PF00397	0.414
LIG_14-3-3_CanoR_1	92	100	PF00244	0.472
LIG_Actin_WH2_2	93	110	PF00022	0.535
LIG_BRCT_BRCA1_1	139	143	PF00533	0.500
LIG_FHA_1	213	219	PF00498	0.510
LIG_FHA_2	100	106	PF00498	0.528
LIG_FHA_2	111	117	PF00498	0.400
LIG_FHA_2	191	197	PF00498	0.544
LIG_FHA_2	56	62	PF00498	0.393
LIG_Integrin_RGD_1	194	196	PF01839	0.476
LIG_LIR_Apic_2	2	8	PF02991	0.414
LIG_LIR_Apic_2	228	234	PF02991	0.788
LIG_LIR_Gen_1	196	205	PF02991	0.494
LIG_LIR_Nem_3	196	202	PF02991	0.425
LIG_NRBOX	154	160	PF00104	0.525
LIG_SH2_CRK	253	257	PF00017	0.652
LIG_SH2_GRB2like	88	91	PF00017	0.474
LIG_SH2_PTP2	231	234	PF00017	0.597
LIG_SH2_STAT5	18	21	PF00017	0.498
LIG_SH2_STAT5	199	202	PF00017	0.539
LIG_SH2_STAT5	231	234	PF00017	0.676
LIG_SH2_STAT5	41	44	PF00017	0.412
LIG_SH2_STAT5	5	8	PF00017	0.611
LIG_SH3_3	135	141	PF00018	0.491
LIG_SH3_3	229	235	PF00018	0.642
LIG_SH3_3	73	79	PF00018	0.646
LIG_TRFH_1	231	235	PF08558	0.621
LIG_UBA3_1	168	177	PF00899	0.524
MOD_CK1_1	148	154	PF00069	0.526
MOD_CK1_1	182	188	PF00069	0.503
MOD_CK1_1	237	243	PF00069	0.698
MOD_CK1_1	28	34	PF00069	0.378
MOD_CK1_1	4	10	PF00069	0.551
MOD_CK2_1	110	116	PF00069	0.511
MOD_CK2_1	271	277	PF00069	0.676
MOD_CK2_1	99	105	PF00069	0.481
MOD_GlcNHglycan	150	153	PF01048	0.468
MOD_GlcNHglycan	187	190	PF01048	0.541
MOD_GlcNHglycan	237	240	PF01048	0.795
MOD_GlcNHglycan	241	244	PF01048	0.683
MOD_GlcNHglycan	245	248	PF01048	0.748
MOD_GlcNHglycan	256	259	PF01048	0.509
MOD_GlcNHglycan	273	276	PF01048	0.569
MOD_GlcNHglycan	93	96	PF01048	0.436
MOD_GSK3_1	164	171	PF00069	0.616
MOD_GSK3_1	179	186	PF00069	0.445
MOD_GSK3_1	197	204	PF00069	0.306
MOD_GSK3_1	212	219	PF00069	0.521
MOD_GSK3_1	234	241	PF00069	0.649
MOD_LATS_1	23	29	PF00433	0.388
MOD_N-GLC_1	148	153	PF02516	0.437
MOD_N-GLC_1	53	58	PF02516	0.560
MOD_NEK2_1	1	6	PF00069	0.633
MOD_NEK2_1	183	188	PF00069	0.510
MOD_PKA_2	162	168	PF00069	0.481
MOD_PKA_2	91	97	PF00069	0.469
MOD_Plk_1	25	31	PF00069	0.383
MOD_Plk_2-3	281	287	PF00069	0.537
MOD_Plk_4	1	7	PF00069	0.566
MOD_Plk_4	164	170	PF00069	0.494
MOD_ProDKin_1	137	143	PF00069	0.500
MOD_ProDKin_1	252	258	PF00069	0.724
MOD_ProDKin_1	4	10	PF00069	0.455
MOD_ProDKin_1	75	81	PF00069	0.405
MOD_SUMO_rev_2	140	148	PF00179	0.535
MOD_SUMO_rev_2	286	295	PF00179	0.633
TRG_ENDOCYTIC_2	199	202	PF00928	0.539
TRG_Pf-PMV_PEXEL_1	157	161	PF00026	0.592
TRG_Pf-PMV_PEXEL_1	22	26	PF00026	0.513

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAJ7	Leptomonas seymouri	40%	100%
A0A0N1PCN3	Leptomonas seymouri	35%	82%
A4HJ55	Leishmania braziliensis	65%	100%
A4I6G9	Leishmania infantum	98%	100%
E9B1M6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q9BHD3	Leishmania major	89%	100%